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- Past Events
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- Seminar: The Cell-Graphs of Cancer (Ambulatory Clinic Building - Telehealth Conference Room ACB1.2345, from 2005-11-09 05:00 to 2005-11-09 06:00)
- Cigdem Gunduz Demir: Department of Computer Science, Rensselaer Polytechnic Institute
- Monte Carlo Simulations of Proton Radiation Cancer Therapy (Duncan Hall 3092, from 2005-10-05 22:00 to 2005-10-06 00:00)
- Cancer affects two out of every three families in America, with an annual cost of approximately $107 billion per year. More than half of the cost goes towards the treatment of breast, lung, and prostate cancer.
- [LECTURE] Whole Genome Sequencing and Imaging-Based Systems Biology ( McMurtry Auditorium Duncan Hall, from 2006-03-19 22:00 to 2006-03-19 23:00)
- Abstract: The whole-genome shotgun sequencing method with paired end- reads has proven rapid and economical, producing high- quality reconstructions of Drosophila (2000), Human (2001) and Mouse (2001), in quick succession. We discuss the overall algorithmic strategy, and the results one can expect by comparing the whole genome assembly of Drosophila against the finished sequence. Because the finishing phase of genome assembly is an order of magnitude more expensive then the shotgun phase, most genomes being sequenced today will never be finished. This makes the goal of building better whole genome assemblers more important than ever. We present a new string-graph approach and several other improvements, giving preliminary results. We also discuss recent advances in sequencing technology. Much hope has been placed on comparative genomics as the easiest route to near-perfect annotation of genes and regulatory elements. We discuss the problem of gene finding and raise the issue that algorithms to date are not performing at the expected level. This leads us to conclude with a segment on the possibility of a program of high-throughput in-situ image analysis in D. melanogaster and C. elegans embryos. We describe preliminary results on limited data sets and extrapolate on what we might be able to infer from such data. We speculate that this may be the best way to understand the developmental cis-regulatory network of the genome from a systems perspective.
- GC4R Monthly Meeting - September 2004 (MDACC FC1.2002, from 2004-09-07 08:00 to 2004-09-07 09:30)
- Monthly meeting of the GC4R. The speaker will be Associate Professor Lydia Kavraki of Rice University.
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