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NLM Computational Biology & Medicine Training Program Directory
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Almeida, Jonas
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Professor
Biostatistics & Applied Math
UT M. D. Anderson Cancer Center
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Email
713/792-9875
Website
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Systems biology, Biomarker identification, Drug / target discovery, Statistical mechanics. Professor Almeida's research interests are directed towards the computational and mathematical tools and mathematical formalisms needed to tackle the twin challenges of identifying biomarkers and targets for drug discovery.
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Annapragada, Ananth
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Associate Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3982
Website
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Targeted drug delivery; computational methods in biomedicine. My research interests are in the area of novel drug delivery systems and MEMS technology applied to drug delivery. Current projects include the development of engineered porous particles for aerosol drug delivery, the simulation of particle flow in pulmonary airways, and targeted drug delivery.
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Aoki, Noriaki
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Assistant Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3930
Website
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Decision science/clinical decision support; Data mining/ modeling in healthcare; Healthcare technology assessment; Clinical informatics in extreme environments
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Bartholomew, L. Kay
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Associate Dean for Educational Programs & Associate Professor
Center for Health Promotion and Prevention Research
UT School of Public Health
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Email
713-500-9630
Website
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Intervention mapping, developing and evaluating theory- and evidence-based program for health education and health promotion, health education planning
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Bernstam, Elmer V.
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Associate Professor of Health Informatics
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3927
Website
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Shareable executable clinical practice guidelines; consumer health informatics; MEDLINE searching (Medline Query-By-Example), informatics in clinical and translational research
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Berry, Donald
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Chair
Biostatistics
UT M. D. Anderson Cancer Center
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Email
713-794-4141
Website
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Clinical trials, statistical data interpretation, genetic predisposition to disease, biological markers
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Boerwinkle, Eric
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Professor
School of Public Health
UT Health Science Center at Houston
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Email
713-500-9800
Website
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Human genetics; epidemiology; heart disease; lipid metabolism; apolipoprotein genes; DNA variation. The objective of research in this laboratory is to understand the role of individual genes in complex physiological systems characterized by gene-gene and gene-environment interactions. The model system used is lipid metabolism and its contribution to atherosclerosis. This laboratory also has experience in typing and characterizing DNA variation in highly repetitive and polymorphic VNTR loci.
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Brandt, Michael
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Associate Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3463
Website
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Biomedical engineering; computational biomedicine; neuroimaging
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Chiu, Wah
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Professor
Biochemistry
Baylor College of Medicine
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Email
713-798-6985
Website
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Structural and Computational Biology of Biological Machines; Biological applications include viruses, ion channels, membranes, oligomeric proteins and cyotskeletal protein complexes. Dr. Chiu has been a leading investigator in the development of electron cryomicroscopy to solve structures of macromolecular assemblies at increasingly high resolutions. Computationally, his group has developed single particle reconstruction software, which has been widely adopted by other investigators. He directs an NIH supported center (http://ncmi.bcm.edu). Among many structures his group has done, Chiu is pursuing the structural studies of viruses including herpes simplex virus, bacteriophages andVenezuelan equine encephalitis virus. His approach includes single particle and tomographic electron cryomicroscopy.
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Coombes, Kevin
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Research Associate Professor
Biostatistics
UT M. D. Anderson Cancer Center
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Email
713-794-4154
Website
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Analysis of microarray data; Development of programming tools for bioinformatics; Multivariable calculus; Applications of differential equations in computing
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Cox, Steven J
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Professor
Comp & Applied Mathematics
Rice University
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Email
713-348-5192
Website
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inference of material properties from electrical and optical recordings from single nerve cells
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Do, Kim-Anh
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Associate Professor
Biostatistics
UT M. D. Anderson Cancer Center
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Email
713-794-4155
Website
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Computational Statistics and Biostatistics, Bioinformatics , Statistical Genetics , Non-parametric statistical methods, including the Bootstrap
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Dunn, Kim
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Assistant Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3913
Website
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Telehealth, E-health, outcomes, quality
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Ethun, Karen
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Executive Director, Keck Center
GCC/Keck Center
Gulf Coast Consortia
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Email
713-348-4753
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GCC/Keck Center Programs
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Fernandez, Maria E.
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Assistant Professor & Director of Diversity Programs
Center for Health Promotion and Prevention Research
UT School of Public Health
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Email
713-500-9626
Website
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Informed decision-making, health promotion planning and evaluation, health informatics, health communications, Hispanic populations
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Fofanov, Yuriy
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Assistant Professor
Computer Sciences
University of Houston
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Email
713-743-8553
Website
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Causality in genetic networks; Microarray technology; Gene/Protein expression; Sequence analysis; Structural identification of nonlinear dependencies; Mathematical methods of discovering non-linear conformities in experimental data; Informativity and planning of experiments on discovering nonlinear regularity
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Francheck, Matthew A.
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Chairman
Mechanical Engineering
University of Houston
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Email
(713) 743-4502
Website
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engineering sciences: Dynamic Systems, Measurement and Control. Linear and nonlinear system identification, information synthesis, multivariable control theory, nonlinear control theory, controller design, diagnostics/prognostics, and targeted adaptive control. Engineering applications: Internal combustion engines, exhaust after-treatment components, noise/vibration control of structures, and health prognostics of cardiovascular and respiratory systems.
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Glueck, Melissa
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Administrative Program Director
Keck Center
Gulf Coast Consortia
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Email
713-348-4563
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Melissa manages the following GCC/Keck Center Training Programs: AHRQ Patient Safety and Quality, Computational and Structural Biology in Biodefense (CSBB), Keck Virus Imaging, Nanobiology, Pharmacoinformatics, and NLM.
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Gorenstein, David G.
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Professor and Deputy Director
The Brown Foundation Institute of Molecular Medicine
UT Health Science Center at Houston
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Email
713-500-2408
Website
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Proteomics and nanomedicine for both diagnostics and therapeutics in both infectious diseases and cancer; structural biology, drug design, nucleic acid and protein chemistry
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Gorry , Tony
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Professor of Computer Science
Jones Graduate School of Management
Rice University
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Email
713-348-6054
Website
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Information technology to support information acquisition, sharing and management in collaborative work.
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Guerra, Rudy
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Associate Professor
Statistics
Rice University
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Email
713-348-5453
Website
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I am generally interested in biological problems with an emphasis in biomedical research
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Hsu, Chiehwen Ed
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Associate Professor of Public Health Informatics
School of Health Information Sciences and School of Public Health
UT Health Science Center at Houston
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Email
Website
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Disaster vulnerability, disability informatics, emergency preparedness & response, and the reduction of health disparities
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Iyengar, M Sriram
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Assistant Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3976
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Dr. Sriram has focused his research in bio-medical informatics Research & Development including mathematical/statistical modeling, algorithms, and software development across diverse areas such as biochemistry, immunohematology, endocrinology, oncology, orthopedics, neural imaging, and clinical trials.
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Jermaine, Christopher M.
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Associate Professor
Computer Science
Rice University
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Email
713-348-5690
Website
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Relational database systems, approximate query processing, physical database design and data mining
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Johnson, Craig
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Associate Professor of Health Informatics
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3923
Website
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Conducting design, analysis, interpretation, and publication of education and health oriented research and evaluation studies; statistics; and Human learning
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Johnson, Todd R.
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Associate Dean for Academics & Associate Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3921
Website
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Patient safety, human factors engineering for medical devices and software, decision making and decision support, computational models of human cognition
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Johnsson, Lennart
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Cullen Distinguished Professor
Computer Sciences
University of Houston
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Email
713-743-3371
Website
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Computational and data grids
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Kakadiaris, Ioannis
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Professor
Computer Science
University of Houston
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Email
713-743-1255
Website
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Biomedical image analysis, modeling, and simulation; Computational biomedicine; Computer vision; Pattern recognition
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Kavraki , Lydia
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Noah Harding Professor of Computer Science & Professor of Bioengineering
Computer Science and Bioengineering
Rice University
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Email
713-348-5737
Website
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Kavraki's group develops computational tools on high-performance systems to model protein structure and function, understand biomolecular interactions and help analyze, in the long run, the molecular machinery of the cell. This is done by integrating sequence information with three-dimensional structural information to capture, represent and exploit relevant molecular motion. Of particular interest are the identification of three-dimensional functional motifs in protein databases, docking of flexible molecules to flexible receptors, computer-assisted drug discovery, and the understanding and compact representation of structural changes in large biomolecular machines.
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Kimmel, Marek
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Professor
Statistics
Rice University
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Email
713-348-5255
Website
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Informatics and statistical modeling of genome dynamics
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Lau, Ching C.
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Associate Professor
Pediatrics
Baylor College of Medicine
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Email
713-798-4543
Website
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molecular biology of pediatric brain and bone tumors and the clinical applications of genomic technologies.
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Leal, Suzanne M.
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Professor
Dept. of Molecular & Human Genetics
Baylor College of Medicine
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Email
713-798-4011
Website
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My interest in statistical genetics/genetic epidemiology lies in the mapping of complex and Mendelian traits and understanding the interactions between genes and between genes and the environment. In addition to applied work of localizing disease loci through statistical genetic methods, I am interested in methodological research.
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Lemon, Stanley
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Dean
Department of Medicine
UT Medical Branch at Galveston
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Email
(409) 772-4793
Website
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The research in my lab focuses on hepatitis C and hepatitis A viruses: two plus-strand RNA viruses that cause significant disease in human populations. We are particularly interested in building better model systems for hepatitis C, and in characterizing the mechanisms by which these virus RNAs initiate cap-independent translation of their polyprotein.
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Lichtarge, Olivier
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Professor
Molecular & Human Genetics
Baylor College of Medicine
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Email
713-798-5646
Website
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Protein functional surfaces; assembly of active complexes
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Ludtke, Steve
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Associate Professor
Biochemistry
Baylor College of Medicine
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Email
713-798-6989
Website
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My work involves the 3D reconstruction of molecules and macromolecules using a technique called single particle reconstruction. My most significant contribution to the field is the development of the EMAN software package (see below), which performs semi-automated processing of individual molecule images to produce accurate 3D reconstructions.
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Luxon, Bruce
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Director, Professor
UTMB Bioinformatics Program, Dept. of Biochemistry and Molecular Biology
UT Medical Branch at Galveston
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Email
409-747-6802
Website
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Metabolomics studies related to diabetes, occupational exposure, cancer, addiction, and infectious disease. We specialize in integrating these data with parallel experiments including genomics, proteomics, kinomics, lipidomics, and LC/MS metabolomics.
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Ma , Jianpeng
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Associate Professor
Bioengineering
Rice University
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Email
713-348-5713
Website
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Simulation of supermolecular complexes; computer-aided drug-design. Our group is using combined experimental and computational methods to study the fusion mechanisms of influenza virus, especially the hemagglutinin-mediated cell membrane fusion. Of particular interest is to derive structural information for intermediates along the pH-triggered conformational transition, which is an extremely difficult problem. We will employ a suite of biophysical techniques including various imagining methods and computer simulation techniques.
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Markham, Christine
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Assistant Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-9646
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Adolescent and child health, including HIV, STD and pregnancy prevention, substance use prevention, chronic disease management, influence of parental factors, qualitative research, outcome and process evaluation
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Milosavljevic, Aleksandar
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Associate Professor
Human Genome Sequencing Center
Baylor College of Medicine
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Email
713-798-8719
Website
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Bioinformatics and Comparative Genomics. Pooled Genomic Indexing (PGI). In a first genome-scale application of PGI, our lab is mapping a whole-genome BAC library of rhesus macaque onto human genomic sequence. Clone-Array Pooled Shotgun Sequencing (CAPSS). Comparative Sequence Assembly. We are further refining and applying methods and software for comparative assembly on the scale of mammalian genomes. Genome-scale Sequence Comparison Methods. One of our goals is to enable comparison of genomes at arbitrary levels of sequence assembly and to enable comparative assembly of shotgun fragments. Genboree (http://www.genboree.org). Genboree is an ¿electronic whiteboard¿ for sharing and development of sequence assemblies and annotations.
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Montague, Jr., P Read
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Professor
Division Of Neuroscience
Baylor College of Medicine
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Email
713-798-3134
Website
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Computational neuroscience - the connection between the physical mechanisms present in real neural tissue and the computational functions that these mechanisms embody. Work in the Montague group also extends into several experimental areas including synaptic physiology, human neuroimaging, and human behavior.
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Morrisett , Joel
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Professor
Medicine Athero & Lipo
Baylor College of Medicine
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Email
713-798-4164
Website
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Imaging, Genomics, and Proteomics of Human Atherosclerosis; elucidating the mechanism(s) whereby Lp[a] exerts its atherogenic effects; The apo[a] protein; Peptide segmenets found in the proline-rich motif of cytokine receptors are under study using the techniques of molecular modeling, circular dichroism, and nuclear magnetic resonance spetroscopy.
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Mullen, Patricia D.
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Professor
School of Public Health
UT Health Science Center at Houston
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Email
713-500-9658
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Health promotion for disadvantaged or incarcerated women; transtheoretical model of behavior change; contraception and STD/HIV risk reduction; informed decision making for cancer and other screening tests; patient education; evaluation methods; systematic review and meta-analysis
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Nakhleh, Luay
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Assistant Professor
Computer Science
Rice University
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Email
713-348-3959
Website
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Bioinformatics and computational biology. In this area I work on reticulate evolution, multi-locus genotype-phenotype inference, and biological signaling networks. Historical linguistics. In this area, I work on developing computational methods for reconstructing the evolution of natural languages and detecting borrowing among them.
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Noebels, Jeffrey L.
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Professor
Department of Neurology
Baylor College of Medicine
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Email
713-798-5860
Website
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Epilepsy and Inherited Neurological Disease
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Palzkill, Timothy
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Chair and Professor
Pharmacology
Baylor College of Medicine
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Email
713-798-5609
Website
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Molecular Basis of Antibiotic Resistance, Functional Genomics of Bacterial Pathogens
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Peters, Clarence (C.J.)
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Professor; Director for Biodefense, Center for Biodefense and Emerging Infectious Diseases
Department of Pathology
UT Medical Branch at Galveston
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Email
409-772-0090
Website
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The pathogenesis and epidemiology of the viral hemorrhagic fevers and other emerging viral infections; Virology, immunology and structural biology applied to this field; Bunyaviridae (phleboviruses such as Rift Valley fever), Arenaviridae (Lassa fever, South American hemorrhagic fevers) and SARS CoV. He works closely with members of the trining center who are specialists in imaging to choose and execute experiments that are of biological significance and to prepare viruses for examination.
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Pettitt, B. Monte
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Cullen Distinguished Professor
Chemistry
University of Houston
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Email
713-743-3263
Website
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Chemical physics; Physical chemistry; Biochemistry; Computer Science; Development of methods for calculating internal conformational structure and interpreting conformational equilibria of biomolecular solutes in aqueous environments; Structural and thermodynamic description of neat polar molecular fluids, including water, ions, polar biomolecular solutes and other condensed phase systems via integral equation and density functional methods; Development of theoretical techniques for the description of the thermodynamics and structure of ionic and anisotropic fluids; Development of methods to compare and search genomes
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Scott , David W
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Noah Harding Professor
Statistics
Rice University
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Email
713-348-6037
Website
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Basic theoretical studies of multivariate probability density estimation, computationally intensive algorithms in statistical computing, and data exploration using advanced techniques in computer visualization
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Serysheva, Irina
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Associate Professor
Biochemistry & Molecular Biology
UT Health Science Center at Houston
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Email
713-500-5523
Website
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Molecular mechanisms underlying ion transport into and out of the cell across the surface membrane, or between different intracellular compartments using structure-function studies of membrane proteins and the macromolecular assemblies they form
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Shegog, Ross
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Assistant Professor of Health Promotion and Behavioral Sciences
Center for Health Promotion and Prevention Research
UT School of Public Health
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Email
713-500-9677
Website
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Application of behavioral theory and methods in the development, implementation, and evaluation of technology-based health promotion and disease-prevention programs; primarily targeting adolescent populations
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Smith, Jack W.
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Dean & Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3925
Website
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Artificial intelligence, modeling problem-solving in healthcare, implementation of decision support and tutoring systems, modeling complex human problem-solving, application of cognitive science to understanding, human-computer interaction
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Subramanian , Devika
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Professor
Computer Science
Rice University
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Email
713-348-5661
Website
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Computational Biology, Conflict forecasting, Adaptive compilers, Machine learning, artificial intelligence, hybrid control, bioinformatics, cognitive science
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Taylor, Wendell
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Associate Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-9635
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Health promotion; CVD risk factors in children; Physical activity in children; Cancer prevention in underserved populations
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Turley, James P.
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Associate Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3924
Website
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Patient health records, electronic health records, knowledge modeling, data display
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Vannucci, Marina
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Professor
Statistics
Rice University
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Email
Website
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Theory and practice of Bayesian variable selection techniques and on the development of wavelet-based statistical models and their application
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Vardi , Moshe Y
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George Professor of Comp Eng
Computer Science
Rice University
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Email
713-348-4834
Website
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Applications of logic to computer science, including database theory, finite-model theory, knowledge in multi-agent systems, computer-aided verification and reasoning, and teaching logic across the curriculum.
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Walters, Scott T.
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Associate Professor
School of Public Health
UT Health Science Center at Houston
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Email
214-648-1519
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College student health and substance abuse prevention, motivational theories of change, mailed and computerized interventions for substance abuse, brief negotiation in medical settings, religious and spiritual aspects of psychology
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Wang, Hongbin
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Associate Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3911
Website
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Spatial cognition; Medical decision making abductive/diagnostic reasoning; Human machine learning; Computational modeling; Human-computer interaction
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Warren , Joe D
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Professor
Computer Science
Rice University
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Email
713-348-5728
Website
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algebraic geometry, computer-aided geometric design, mesh generation, symbolic computation, visualization, subdivision , wavelets
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Watowich, Stanley
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Associate Professor
Biochemistry and Molecular Biology
UT Medical Branch at Galveston
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Email
409-747-4749
Website
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Dr. Watowich has long-standing interest in virus structure, function, host-responses to infection, and antiviral drug development. The laboratory has solved the crystal structures of individual non-structural and structural proteins from alphaviruses, and carried out biochemical and biophysical studies of flavivirus and alphavirus proteins. Structures of intact RNA viruses and their assembly mechanisms are studied by electron cryomicroscopy, image reconstruction, and biophysical techniques. Structure-based computational drug discovery, in vitro inhibition assays, and cell- based replication assays are used to develop antiviral agents.
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Weaver, Scott C.
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Professor
Department of Pathology
UT Medical Branch at Galveston
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Email
409-747-0758
Website
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Our research focuses on the genetics, ecology, evolution and pathogenesis of arthropod-borne viruses (arboviruses), virus-mosquito interactions and vaccine development. We study arboviruses, principally alphaviruses and dengue virus, with emphasis on viral mutations that mediate host range changes, leading to disease emergence. Using confocal microscopy in concert with alphaviruses or replicon virus-like particles that express green fluorescent protein (GFP), we study infection of rodents and horses with alphaviruses, as well as mosquitoes. We also collaborate with Wah Chiu and Stan Watowich on structural studies of Venezuelan equine encephalitis (VEE) virus (TC-83 vaccine strain) using cryoelectron microscopy, and we intend to extend these studies to wild-type strains with the ultimate goal of understanding the structural changes that mediate VEE emergence.
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Zhang, Jiajie
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Associate Dean for Research & Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3922
Website
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Biomedical informatics, electronic health records, human-centered computing, cognitive science in medicine, information display and visualization, medical error, decision making
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Zhang, Li
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Assistant Professor
Biostatistics
UT M. D. Anderson Cancer Center
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Email
713-563-4298
Website
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Computational genome biology; gene expression microarray data modeling; networks of gene expression regulation
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Zhang, Ming
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Assistant Professor
Biostatistics & Applied Math
UT M. D. Anderson Cancer Center
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Email
(713) 792-2607
Website
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docking; computer-assisted drug design; protein folding; mathematical modeling; algorithms
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