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GCC Chemical Genomics Directory
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Annapragada, Ananth
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Associate Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3982
Website
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Targeted drug delivery; computational methods in biomedicine. My research interests are in the area of novel drug delivery systems and MEMS technology applied to drug delivery. Current projects include the development of engineered porous particles for aerosol drug delivery, the simulation of particle flow in pulmonary airways, and targeted drug delivery.
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Arap, Wadih
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Professor
Genitourinary Medical Oncology
UT M. D. Anderson Cancer Center
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Email
713/792-3871
Website
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Pathologic neovascularization, angiogenesis inhibitors, biological tumor markers, drug delivery system. Our research is aimed at targeting blood vessels for delivery of diagnostic and therapeutic agents by using probes that can bind to specific addresses in selective vascular beds.
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Ayers, Steve
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Diabetes and Metabolic Disease
The Methodist Hospital Research Institute
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Email
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Genomic medicine
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Baraniuk, Richard
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Professor
Elec & Comp Engineering
Rice University
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Email
713-348-5132
Website
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Multiscale, computational signal and image processing
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Barrett, Alan
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Professor
Pathology
UT Medical Branch at Galveston
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Email
(409) 772-6662
Website
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My research program focuses on two groups of viruses: flaviviruses and bunyaviruses. Both groups contain viruses that are transmitted by arthropods, such as mosquitoes and ticks, and are given the general term of
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Barron, Andrew
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Charles W. Duncan-Welch Prof.; Professor of Materials Science
Chemistry
Rice University
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Email
713-348=5610
Website
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Research in the Barron Group focuses on the chemistry and materials science of aluminum and its related elements in the periodic table. Our initiatives encompass problems across the fields of traditional inorganic chemistry, organometallic chemistry, nanoscale science and technology, and materials science.
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Bast, Robert
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Professor
Experimental Therapeutics; Translational Research
UT M. D. Anderson Cancer Center
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Email
713-792-7743
Website
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Signal transduction, ovarian neoplasms, breast neoplasms, biological markers, tumor suppressor genes. Our laboratory has focused on the biology, detection, prevention, and treatment of epithelial ovarian and breast cancers. Over the past decade, we have found that ovarian cancer is generally a clonal disease and have focused our attention on molecular changes that occur during malignant transformation.
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Bates, Theodore
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Professor
Pharmacokinetics
Texas Southern University
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Email
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Bell, Edward
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Assistant Professor
Pharmaceutics
TSU
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Email
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Berry, Donald
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Chair
Biostatistics
UT M. D. Anderson Cancer Center
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Email
713-794-4141
Website
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Clinical trials, statistical data interpretation, genetic predisposition to disease, biological markers
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Boerwinkle, Eric
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Professor
School of Public Health
UT Health Science Center at Houston
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Email
713-500-9800
Website
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Human genetics; epidemiology; heart disease; lipid metabolism; apolipoprotein genes; DNA variation. The objective of research in this laboratory is to understand the role of individual genes in complex physiological systems characterized by gene-gene and gene-environment interactions. The model system used is lipid metabolism and its contribution to atherosclerosis. This laboratory also has experience in typing and characterizing DNA variation in highly repetitive and polymorphic VNTR loci.
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Bornmann, William
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Professor, Synthetic Chemistry
Experimental Therapeutics
UT M. D. Anderson Cancer Center
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Email
713-563-0081
Website
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Synthesis, purification and characterization of various novel biologically active molecules that can be developed into new optical, PET and MRI/MRSI imaging probes; Synthesis of precursor molecules for radiolabeling, paramagnetic and fluorescent labeling.
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Brasier, Allan
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Professor
Internal Medicine - Endocrinology
UT Medical Branch at Galveston
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Email
Website
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cellular mechanisms of genetic responses to inflammatory hormones in the liver (the hepatic acute-phase response) and the respiratory epithelium (the pulmonary cytokine cascade)
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Briggs, James
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Associate Professor
Biology and Biochemistry
University of Houston
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Email
713-743-8366
Website
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Computational studies of protein structure and function; Our research is focused on computational studies of protein structure and function, inhibitor design, investigations of possible inhibitor resistance pathways, and development of methods for the above project areas. Targets for these studies include those important in the treatment of AIDS, cancer, bacterial infections, and other disease states. In addition, we work on inhibitors to aid in biowarfare defense (botulinum neurotoxins, anthrax toxin).
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Brinkley, William (Bill)
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VP Dean Of Grad Sch
Corporate Officers-Molecular and Celular Biology
Baylor College of Medicine
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Email
713-798-5263
Website
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We seek to understand the molecular basis of errors and defects in the nucleus and mitotic apparatus (MA) that cause aneuploidy. Our research utilizes molecular biology and genetic approaches combined with digital image analysis at the light and electron microscopy levels to analyze normal and defective features of chromosome condensation, attachment and alignment on the spindle and movements during mitosis in normal and neoplastic cells.
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Butler, Bruce D.
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Ast VP Research & Technology
Anesthesiology
UT Health Science Center at Houston
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Email
713-500-6231
Website
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Byrne, John
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Professor and Chairman
Medical School
UT Health Science Center at Houston
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Email
713-500-5602
Website
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Dr. Byrne's research interests involve elucidating the neuronal and molecular mechanisms underlying learning and memory
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Caskey, Tom
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Director and Chief Executive Officer
Institute of Molecular Medicine
UT Health Science Center at Houston
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Email
Website
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Cavasotto, Claudio
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Assistant Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3934
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Computational Biochemistry & Biophysics, and Drug Discovery: Computer-aided drug discovery; protein modeling; study of protein interaction and function; chemoinformatics; simulation theory, force-field development. Studied biomolecular systems include, but not limited to, hormone nuclear receptors, protein kinases and GPCRs.
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Chang, Rowen
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Professor & Director of the Center for Protein Chemistry
Institute of Molecular Medicine
UT Health Science Center at Houston
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Email
+1 (713) 500-24
Website
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Chiu, Wah
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Professor
Biochemistry
Baylor College of Medicine
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Email
713-798-6985
Website
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Structural and Computational Biology of Biological Machines; Biological applications include viruses, ion channels, membranes, oligomeric proteins and cyotskeletal protein complexes. Dr. Chiu has been a leading investigator in the development of electron cryomicroscopy to solve structures of macromolecular assemblies at increasingly high resolutions. Computationally, his group has developed single particle reconstruction software, which has been widely adopted by other investigators. He directs an NIH supported center (http://ncmi.bcm.edu). Among many structures his group has done, Chiu is pursuing the structural studies of viruses including herpes simplex virus, bacteriophages andVenezuelan equine encephalitis virus. His approach includes single particle and tomographic electron cryomicroscopy.
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Choudhary, Sanjeev
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Instructor
Biochemistry and Molecular Biology
UT Medical Branch at Galveston
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Email
Website
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Mechanism of Respiratory Syncytial Virus (RSV)- induced airway inflammation
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Chow , Dar-chone
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Assistant Professor
Chemistry
University of Houston
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Email
713-743-1798
Website
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One research goal in our laboratory is to understand the basis of conformational changes in the function of a protein.
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Clark, Richard
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Professor
Integrative Biology and Pharmacology
UT Health Science Center at Houston
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Email
Website
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Mechanisms of activation and desensitization of the human â2-adrenergic receptor (â2AR), and its relevance to various diseases in particular asthma
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Clementi , Cecilia
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Associate Professor
Chemistry
Rice University
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Email
713-348-3485
Website
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Theory of protein Folding; computational molecular biology
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Collins, Alan
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Research Associate
Medicine
The Methodist Hospital Research Institute
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Email
713-441-2027
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diabetes, endocrinology, diabetic cardiomyopathy
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Cook, Richard
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Professor
Immunology
Baylor College of Medicine
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Email
713-798-6318
Website
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Structure and Function of Class I MHC Molecules
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Cooney, Austin
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Assistant Professor
Cell Biology
Baylor College of Medicine
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Email
713-790-1275
Website
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Regulation of gene expression by orphan nuclear receptors
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Cooper, Cary
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Pharmacology
UT Medical Branch at Galveston
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Email
409-772-1902
Website
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Cui, Kemi
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TMHRI
The Methodist Hospital Research Institute
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Email
713-441-3549
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Neuroprotection drugs and brain tumors, image-based screening
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Cunningham, Kathryn
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Professor
Pharmacology and Toxicology
UT Medical Branch at Galveston
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Email
Website
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Neural basis underlying the effects of psychoactive drugs
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Cunningham, Sonia
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Associate Professor
Pediatrics Leukocyte Biology
Baylor College of Medicine
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Email
713-798-0370
Website
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Czerwinski, Edmund
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Human Biological Chemistry & Genetics
UT Medical Branch at Galveston
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Email
409-772-3287
Website
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Danforth, Rebecca
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Postdoctoral Fellow
Radiation Oncology
The Methodist Hospital Research Institute
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Email
713-441-4653
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DNA damages
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Davies, Michael
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Assistant Professor
Melanoma Medical Oncology
UT M. D. Anderson Cancer Center
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Email
Website
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Davies, Peter
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Ex VP Research
Administration
UT Health Science Center at Houston
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Email
713-500-3082
Website
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biology and pharmacology of the Retinoid X Receptor (RXR), of the factors controlling the expression of the enzyme tissue transglutaminase
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Deem , Michael W.
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John W. Cox Professor
Bioengineering
Rice University
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Email
713-348-5852
Website
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Vaccine design; physical theories of pathogen evolution and the immune response; Newton's laws of biology.
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Deng, Tuo
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Postdoctoral Fellow
Diabetes and Metabolic Disease
The Methodist Hospital Research Institute
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Email
713-441-4783
Website
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Denner, Larry
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Internal Medicine
UT Medical Branch at Galveston
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Email
409-772-8703
Website
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Dessauer, Carmen
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Associate Professor
Medical School
UT Health Science Center at Houston
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Email
713-500-6308
Website
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Structural, biochemical, and molecular biology techniques; Dynamics of cAMP production by signaling complexes at the plasma membrane
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Doursout, Marie-Francoise
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Associate Professor
Anesthesiology
UT Health Science Center at Houston
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Email
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Drezek, Rebekah A.
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Professor
Bioengineering
Rice University
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Email
713-348-3011
Website
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Nanotechnology; molecular imaging; biophotonics
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Dubinsky, William
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Professor
Integrative Biology & Pharm
UT Health Science Center at Houston
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Email
+1 (713) 500-63
Website
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Eikenburg, Doug
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Chair and Associate Professor of Pharmacology
Pharmacological and Pharmaceutical Sciences
University of Houston
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Email
713-743-1217
Website
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Estes, Mary K.
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Professor
Virology & Microbiology
Baylor College of Medicine
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Email
713-798-3585
Website
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Molecular biology and structure of virus assembly; multidisciplinary approaches to probe the structure and molecular biology of GI viruses to understand the basic mechanisms that control virus replication, morphogenesis, virus-host interactions, and pathogenesis.
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Fernandez, Susan
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Admin Services Officer III
EVP Research
UT Health Science Center at Houston
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Email
1 (713) 500-347
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Gao, Xiaolian
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Professor
Chemistry
University of Houston
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Email
713-743-2805
Website
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Biophysical and organic chemistry; Research in the laboratory is at the interfaces of chemistry and biological sciences. Our work focuses on two areas: (1) Biological NMR of nucleic acids, proteins, and their complexes with ligand molecules. (2) Microarray BIOCHIP technologies in synthesis and applications.
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Gelovani, Juri
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Radiology and Neurology
UT M. D. Anderson Cancer Center
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Email
713-563-3343
Website
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Gibbs , Richard
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Professor
Human Genome Sequencing Center
Baylor College of Medicine
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Email
713-798-6539
Website
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The Human Genome Project; molecular basis of human genetic diseases; molecular evolution.
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Gilbert, Hiram
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Associate Dean Graduate School Professor
Biochemistry
Baylor College of Medicine
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Email
713-798-5880
Website
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Protein Folding
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Gilbertson, Scott R.
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M. D. Anderson Professor
Chemistry
University of Houston
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Email
713-743-8821
Website
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Development of Chemistry for Small Molecule Library Synthesis; Total Synthesis and Medicinal Chemistry of Biologically Important Natural Products; Rhodium Catalyzed Synthesis of Medium Sized Rings; Peptide Based Catalysts.
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Gomer, Richard H.
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Professor | Investigator, H H M I
Biochemistry and Cell Biology
Rice University
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Email
713-348-4872
Website
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Determination and maintenance of cell fate, cell density sensing, tissue size regulation, Scleroderma, cataclysmic variable stars
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Gorenstein, David G.
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Professor and Deputy Director
The Brown Foundation Institute of Molecular Medicine
UT Health Science Center at Houston
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Email
713-500-2408
Website
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Proteomics and nanomedicine for both diagnostics and therapeutics in both infectious diseases and cancer; structural biology, drug design, nucleic acid and protein chemistry
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Gupte, Anisha
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Postdoctoral Fellow
Physiology
The Methodist Hospital Research Institute
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Email
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diabetes, obesity, and lipids
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Hafner, Jason
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Associate Professor
Physics and Astronomy
Rice University
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Email
713-348-3205
Website
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Nanometer-scale tools to study biological systems
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Halas, Naomi
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Stanley C. Moore Professor
Elec & Comp Engineering
Rice University
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Email
713-348-5611
Website
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Development of nanoscale tools and devices for intracellular sensing, spectroscopy and detection of biomolecules, and applications in cancer diagonostics and therapeutics
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Hamilton, Susan
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Professor
Academic Department
Baylor College of Medicine
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Email
713-798-5704
Website
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Hartgerink, Jeffery Dale
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Associate Professor
Chemistry
Rice University
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Email
713-348-4142
Website
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Supramolecular chemistry
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Hayes, Barbara
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Dean, College Of Pharmacy and Health Sciences and Professor
Pharmacology
TSU
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Email
713-313-7280
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Molecular mechanisms involved in inflammatory and vascular proliferative disease processes
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Higgins, Catherine
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Research Consortia
Gulf Coast Consortia
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Email
713-348-4772
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Hilser, Vincent
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Professor
Biochemistry and Molecular Biology
UT Medical Branch at Galveston
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Email
409-747-6813
Website
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Research in our lab is focused on the experimental characterization of conformational fluctuations, the development and refinement of a general ensemble-based model for fluctuations, and the projection of this thermodynamic model into genomic analysis. Our goals are to unify the description of protein behaviors in such a way as to understand their relationships at the phenomenological level, to codify these relationships in a simple structure-based model, and to apply our model to a number of experimental systems that can be used to test and refine our approach.
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Hsueh, Willa
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Director, Diabetes Research Center
Medicine
The Methodist Hospital Research Institute
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Email
713-441-2520
Website
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Diabetes, obesity, and lipids
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Hussain, Tahir
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Assistant Professor
Department of Pharmacological
University of Houston
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Email
(713) 743-1274
Website
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To understand the role of renal angiotensin and dopamine receptors and associated cellular signaling pathways in obesity/diabetes related hypertension
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Jayaraman, Vasanthi
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Associate Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
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Email
713-500-6236
Website
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Structure and function; membrane bound proteins; ion channels
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Johnsson, Lennart
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Cullen Distinguished Professor
Computer Sciences
University of Houston
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Email
713-743-3371
Website
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Computational and data grids
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Kavraki , Lydia
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Noah Harding Professor of Computer Science & Professor of Bioengineering
Computer Science and Bioengineering
Rice University
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Email
713-348-5737
Website
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Kavraki's group develops computational tools on high-performance systems to model protein structure and function, understand biomolecular interactions and help analyze, in the long run, the molecular machinery of the cell. This is done by integrating sequence information with three-dimensional structural information to capture, represent and exploit relevant molecular motion. Of particular interest are the identification of three-dimensional functional motifs in protein databases, docking of flexible molecules to flexible receptors, computer-assisted drug discovery, and the understanding and compact representation of structural changes in large biomolecular machines.
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Kirken, Robert
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Assistant Professor
Integrative Biology & Pharm
UT Health Science Center at Houston
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Email
+1 (713) 500-63
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Koelbel , Charles H
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Research Scientist
Computer Science
Rice University
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Email
713-348-5868
Website
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Chuck Koelbel's research interests center on mapping algorithms and programs onto distributed memory multiprocessors.
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Kripke, Margaret
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EVP & Chief Academic Officer/ Professor of Immunology
Administration
UT M. D. Anderson Cancer Center
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Email
713-745-4495
Website
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Photoimmunology, ultraviolet carcinogenesis, tumor antigens, skin cancer
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Kumar, Rakesh
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Professor
Molecular and Cellular Oncology
UT M. D. Anderson Cancer Center
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Email
713-745-3558
Website
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Growth factor signaling, chromatin remodeling, transcription regulation, and mammary gland development and cancer
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Kurosky, Alexander
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Human Chemistry & Genetics
UT Medical Branch at Galveston
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Email
409-772-2771
Website
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Lee, James C.
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Professor
Biochemistry and Molecular Biology
UT Medical Branch at Galveston
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Email
409-772-2281
Website
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My laboratory is interested in elucidating the molecular mechanisms of regulation, in particular, the ground rules employed in recognizing specific targets and transmitting of signals among these macromolecular components.
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Legge, Glen
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Assistant Professor
Biology and Biochemistry
University of Houston
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Email
713-743-8380
Website
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structural biology to link the fields of biology and chemistry by an understanding of the molecular mechanisms of biological processes
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Lemon, Stanley
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Dean
Department of Medicine
UT Medical Branch at Galveston
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Email
(409) 772-4793
Website
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The research in my lab focuses on hepatitis C and hepatitis A viruses: two plus-strand RNA viruses that cause significant disease in human populations. We are particularly interested in building better model systems for hepatitis C, and in characterizing the mechanisms by which these virus RNAs initiate cap-independent translation of their polyprotein.
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Liang, Dong
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Associate Professor and Chair of Pharmaceutical Sciences
Pharmaceutical Sciences
TSU
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Email
713-313-1885
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Mebendazole in the suppression of tumor growth and inhibition of cancer cell growth
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Lichtarge, Olivier
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Professor
Molecular & Human Genetics
Baylor College of Medicine
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Email
713-798-5646
Website
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Protein functional surfaces; assembly of active complexes
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Lin, Shiaw-Yih (Phoebus)
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Assistant Professor
Systems Biology
UT M. D. Anderson Cancer Center
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Email
713 - 563-4217
Website
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DNA damage checkpoint and DNA repair; genetic and chemical screens; cancer stem cells; cancer metastasis. My lab is interested in studying genes involved in DNA damage responses and DNA repair, cancer stem cells phenotypes and cancer metastasis.
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Lokhandwala, Mustafa F.
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Executive Vice Dean for Research and Professor of Pharmacology
Department of Pharmacological and Pharmaceutical Studies
University of Houston
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Email
(713) 743-1259
Website
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Loose, David
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Associate Professor & Dir
Integrative Biology & Pharm
UT Health Science Center at Houston
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Email
(713) 500-7440
Website
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Lopez-Berestein, Gabriel
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Bioimmunotherapy
UT M. D. Anderson Cancer Center
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Email
713-792-8143
Website
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Lu, Yiling
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Assistant Professor
Molecular Therapeutics
UT M. D. Anderson Cancer Center
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Email
(713) 563-4218
Website
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Luxon, Bruce
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Director, Professor
UTMB Bioinformatics Program, Dept. of Biochemistry and Molecular Biology
UT Medical Branch at Galveston
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Email
409-747-6802
Website
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Metabolomics studies related to diabetes, occupational exposure, cancer, addiction, and infectious disease. We specialize in integrating these data with parallel experiments including genomics, proteomics, kinomics, lipidomics, and LC/MS metabolomics.
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Lyon, Chris
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Medicine
The Methodist Hospital Research Institute
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Email
713-441-2665
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diabetes, obesity, and lipids
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Ma , Jianpeng
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Associate Professor
Bioengineering
Rice University
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Email
713-348-5713
Website
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Simulation of supermolecular complexes; computer-aided drug-design. Our group is using combined experimental and computational methods to study the fusion mechanisms of influenza virus, especially the hemagglutinin-mediated cell membrane fusion. Of particular interest is to derive structural information for intermediates along the pH-triggered conformational transition, which is an extremely difficult problem. We will employ a suite of biophysical techniques including various imagining methods and computer simulation techniques.
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Mancini, Michael A.
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Associate Professor
Cell Biology
Baylor College of Medicine
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Email
713-798-8952
Website
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Functional relationship(s) between dynamic nuclear organization and transcription
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Martin, Emil
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Assistant Professor
IMM - Cell Imaging
UT Health Science Center at Houston
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Email
Website
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Molecular basis of nitric oxide/cGMP signaling in cells
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Mathew, Omana
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Research Associate
Pharmacy and Health Sciences
Texas Southern University
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Email
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Matsuda, Seiichi
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Professor
Chemistry
Rice University
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Email
713-348-6158
Website
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Recombinant biosynthetic approaches to natural product biosynthesis. Directed evolution and DNA shuffling to generate new oxidosqualene cyclases. Metabolic engineering to produce terpenes.
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Matthews, Kathleen S
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Stewart Memorial Professor, Biochemistry/Cell Bio
Wiess School of Natural Sciences
Rice University
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Email
713-348-4871
Website
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Structure and function of genetic regulatory proteins
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McMurray, John
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Associate Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
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Email
713-745-3763
Website
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Bio-organic chemistry, peptide and peptidomimetic chemistry, structure-guided drug design, protein-protein interaction, enzyme inhibitor design. Our work concerns the design of inhibitors of important protein-protein interactions with the overall goal of developing chemotherapeutic agents as well as reagents to probe signal transduction mechanisms. Our current targets are the STAT (signal transduction and activator of transcription) proteins. Our strategy is to find high affinity peptides to inhibit target protein-protein interactions, determine which parts of the peptide contributes to binding energy, determine the bound conformation, then combine this information to develop small molecule inhibitors that mimic the action of the peptide. Another strategy is screening a small molecule library to find leads.
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Mehta, Chander
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Professor
Pharmaceutical Sciences
Texas Southern University
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Email
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Merényi, Erzsébet
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Research Professor
Electrical & Computer Engineering
Rice University
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Email
713-348-3595
Website
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Artificial neural networks, self-organized learning, pattern recognition, segmentation and classification of high-dimensional patterns, precision data mining, knowledge discovery. Application to information extraction from multi- and hyperspectral data/imagery, for 1. planetary surface composition identification, geologic, soil, resource mapping, environmental monitoring and 2. medical image and data analysis.
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Mikos, Antonios G.
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J. W. Cox Professor, Director of J. W. Cox Lab for Biomedical Engineering
Bioengineering
Rice University
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Email
(713)348-5355
Website
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Biomaterials; drug delivery; gene therapy; tissue engineering. The synthesis, processing, and evaluation of new biomaterials for tissue engineering, scaffolds for three-dimensional cell culture, conduits for guided tissue regeneration, substrates for targeted cell adhesion, carriers for controlled drug delivery, and non-viral vectors for gene therapy. We are also developing new CAD/CAM and polymer chemistry fabrication technologies for the production of synthetic biomimetic materials that exhibit the mechanical responsiveness and biochemical processing capabilities of living cells and tissues.
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Mills, Gordon
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Professor and Chair
Department of Molecular Therapeutics
UT M. D. Anderson Cancer Center
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Email
713-563-4200
Website
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Our research program aims to identify the mechanisms by which normal cells (lymphocytes) and tumor cells (ovarian and breast cancer) perceive and respond to their environment. The mission of the laboratory is to understand the mechanisms by which signal transduction is linked to proliferation, invasion, and programmed cell death in T lymphocytes and in breast and ovarian cancer.We recently identified a unique phospholipid growth factor, OCAF, in the ascites of ovarian cancer patients. We will explore the role of OCAF in early diagnosis, establishment of prognosis, monitoring of therapy, and therapy of breast and ovarian cancer patients.
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Moore, David
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Professor
Cell Biology
Baylor College of Medicine
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Email
713-798-3313
Website
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Functions of Nuclear Hormone Receptors. Current efforts focus on three that have emerged as key regulators of metabolic pathways in the liver: CAR, FXR and SHP. We use pharmacologic and mouse knockout approaches to define the metabolic regulatory functions of the nuclear hormone receptors
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Morris, Andrew
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Associate Professor
Integrative Biology & Pharm
UT Health Science Center at Houston
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Email
(713) 500-6681
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The cellular mechanisms leading to the attainment and maintenance of membrane asymmetry (cellular polarization); cellular factors that facilitate apical membrane vesicular trafficking (movement) and targeting (direction) and, consequently, how transport vesicules containing newly-synthesized ion channels regulate transepithelial Cl secretion. We study the polarized movement of the cAMP-activatable Cl channel, the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in differentiating epithelial cells. Utilizing modern physiological (patch-clamp), morphometric (real time confocal ratio-metric fluorescence) and molecular techniques, we are now in the process of identifying factors that facilitate the movement of CFTR-containing apical targeting vesicles. Lastly, my laboratory is also involved in the study of intracellular second messengers, in particular the role of inositol polyphosphates in the modulation of [Ca2+]i and the activation of Ca2+-sensitive ion channels in epithelial cells. Three-dimensional computer modelling of [ion] with predefined time frames allows us to compartmentalize ion mediated signal transduction at the subcellular level.
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Mueller, Peter
|
Professor
Biostatistics & Applied Math
UT M. D. Anderson Cancer Center
|
Email
713-563-4296
Website
|
|
Numerical integration in Bayesian Statistics, Markov Chain Monte Carlo methods, Simulation based optimal design, Mixture of Dirichlet process models, Neural network models, Longitudinal data models, Pharmacokinetic/pharmacodynamic models, Case-control studies, Hierarchical models, Dynamic models, Nonparametric Bayes.
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Murad, Ferid
|
Scientific Director ; RegProf, Chr & Dunn DistCh IBP
IMM ; Integrative Biology & Pharm
UT Health Science Center at Houston
|
Email
(713) 500-7509
Website
|
|
My research focuses on the formation, metabolism and function of nitric oxide and cyclic GMP as they participate in various cellular signaling processes. Some of our current research is focusing on the formation of peroxynitrite from nitric oxide and the nitration of various cellular proteins.
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Murray, Barbara
|
Professor
Internal Medicine, Infectious
UT Health Science Center at Houston
|
Email
(713) 500-6767
Website
|
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The genetic and biochemical mechanisms of resistance to antibiotics and bacterial pathogenicity, particularly relating to enterococci, and molecular epidemiologic typing methods; Defining the enterococcal antigens that elicit antibody responses in infected patients, generation of isogenic mutants for studies of virulence, testing the potential protective effect of antiserum, identification of gene(s) encoding adherence to extracellular matrix proteins and characterization of a polysaccharide biosynthesis gene cluster of E. faecalis
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O'Malley, Marcia
|
Assistant Professor
Mechanical Engr & Materials Sci
Rice University
|
Email
713-348-3545
Website
|
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Modeling, design, and control of haptic interfaces; Modeling, design, and control of telemanipulation and human augmentation systems; Study of human-robot interactions.
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Olaleye, Omonike
|
Assistant Professor
Pharmacology
Texas Southern University
|
Email
|
|
Development of novel therapeutics for the treatment of Mycobacterium tuberculosis infection
|
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Palzkill, Timothy
|
Chair and Professor
Pharmacology
Baylor College of Medicine
|
Email
713-798-5609
Website
|
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Molecular Basis of Antibiotic Resistance, Functional Genomics of Bacterial Pathogens
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Parry, Ronald J.
|
Professor
Chemistry
Rice University
|
Email
713-348-2446
Website
|
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Biosynthesis of natural products and the mechanisms of enzymatic reactions; Investigations of the biosynthesis of the phytotoxin coronatine, the antibiotic aristeromycin, and the antitumor agents sparsomycin and valanimycin.
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Pasquali, Matteo
|
Associate Professor
Chemical & Biomolecular Engineering
Rice University
|
Email
713-348-5830
Website
|
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The interaction of flow and liquid micro- and nano-structure; Microstructured liquids; Computational modeling of processing flows; Free surface flows; Visualization of flowing single DNA molecules; Rheology and phase behavior of Single-Walled Carbon Nanotubes; Rheology and microstructure of Polymeric Nanoparticles (particoils); Rheology and microstructure of Emulsions; Single-molecule behavior of semiflexible macromolecules.
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Perachio, Adrian
|
Professor Emeritus
Otolaryngology
UT Medical Branch at Galveston
|
Email
409-747-3770
Website
|
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Vestibular Physiology; Basic and applied research on the effects of the space environment on human health
|
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Pettitt, B. Monte
|
Cullen Distinguished Professor
Chemistry
University of Houston
|
Email
713-743-3263
Website
|
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Chemical physics; Physical chemistry; Biochemistry; Computer Science; Development of methods for calculating internal conformational structure and interpreting conformational equilibria of biomolecular solutes in aqueous environments; Structural and thermodynamic description of neat polar molecular fluids, including water, ions, polar biomolecular solutes and other condensed phase systems via integral equation and density functional methods; Development of theoretical techniques for the description of the thermodynamics and structure of ionic and anisotropic fluids; Development of methods to compare and search genomes
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Phillips, Kevin
|
TMHRI
The Methodist Hospital Research Institute
|
Email
Website
|
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Diabetes, obesity, and lipids
|
|
Plunkett, William
|
Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
|
Email
713-792-3335
Website
|
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Cell cycle regulation, DNA repair, DNA synthesis, clinical pharmacology; Developing a molecular and biochemical understanding of how nucleoside analogues kill cells and how cells become resistant to these agents and to apply this knowledge to the design of clinical trials of combination therapies that will optimize therapeutic activity
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Poon, Ivy
|
Associate Professor
Pharmacy and Health Sciences
Texas Southern University
|
Email
713-313-4400
|
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Prasad, B.V.
|
Professor
Biochemistry
Baylor College of Medicine
|
Email
713-798-5686
Website
|
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Structure-function relationships in medically important viruses. Three-dimensional structural analyses on viruses that are causative agents of endemic severe diarrhea in humans. These viruses include rotavirus, calicivirus, and Norwalk virus.
|
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Price, Jeffrey H.
|
Associate Professor
The Burnham Institute
|
Email
(858) 646-3162
Website
|
|
Signal Transduction; Stem Cells & Regeneration; Automated analytical microscopy research for tissue proteomics; Tracking of cell migration and differentiation; Rare cell diagnostics
|
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Priebe, Waldemar
|
Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
|
Email
713-792-3777
Website
|
|
Drug Design, Kinase Inhibitors, DNA Binding Agents, Drug Resistance, Hypoxia
|
|
Proll, Melissa
|
Dir, Rsrch Ed, Int & Compl
EVP Research
UT Health Science Center at Houston
|
Email
(713) 500-3192
|
|
Quiocho, Florante
|
Professor
Hhmi Biochemistry
Baylor College of Medicine
|
Email
713-798-6565
Website
|
|
Structural Biophysics and Biology; X-Ray Crystallography of Proteins; Molecular Recognition and Protein-Ligand Interactions. Our research interest is centered on the study of the tertiary structure and function of proteins and enzymes at atomic resolution.
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Ranganna, Kasturi
|
Research Scientist
Pharmacy and Health Sciences
Texas Southern University
|
Email
|
|
Richards-Kortum, Rebecca
|
Stanley C. Moore Professor Professor and Department Chair
Bioengineering
Rice University
|
Email
713-348-3823
Website
|
|
Her research centers on new, non-invasive cancer detection technologies that use high-resolution, optical imaging; the use of fluorescent imaging agents for cancer detection; biophysical studies of the light-scattering properties of cells and tissues; and the use of fiber-optic sensors for in vivo detection of cancer
|
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Ridge, Kevin
|
Associate Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
|
Email
(713) 500-5908
Website
|
|
Dynamic aspects of integral membrane protein structure, development and application of general approaches for the large-scale expression and purification of GPCR's
|
|
Rosner, Gary
|
Professor
Biostatistics & Applied Math
UT M. D. Anderson Cancer Center
|
Email
713/563-4285
Website
|
|
Bayesian methods; clinical trial design and analysis; longitudinal data models; population pharmacokinetics and pharmacodynamics; survival analysis
|
|
Ruan, Kehe
|
Professor
Pharmacological and Pharmaceutical Sciences
University of Houston
|
Email
713-743-1771
Website
|
|
Using small compounds/peptide/protein/gene/cells to develop novel approaches targeting Vascular Diseases (such as stroke and heart diseases), cancers and tissue regenerations
|
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Safe, Stephen
|
Distinguished Professor; Director, Center for Environmental and Genetic Medicine
Veterinary Physiology and Pharmacology and Institute of Biosciences and Technology
TAMU
|
Email
979-845-5988
Website
|
|
Toxicology and molecular biology of estrogenic and antiestrongenic compounds; molecular mechanisms of estrogen receptor and Ah receptor action and their crosstalk in breast cancer cells
|
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San, Ka-Yiu
|
E.D. Butcher Professor
Bioengineering
Rice University
|
Email
713-798-5361
Website
|
|
Genomic and metabolic engineering; biochemical engineering; biotechnology. My research laboratory is mainly concerned with the development of new concepts and novel ways of altering metabolic routes in Escherichia coli using recombinant DNA technology to improve cellular activities and achieve more advanced production systems.
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Sarkar, Poonam
|
Research Associate
Pharmacy and Health Sciences
Texas Southern University
|
Email
|
|
Schein, Catherine
|
Associate Professor
Biochemistry and Molecular Biology, Microbiology and Immunology
UT Medical Branch at Galveston
|
Email
409-747-6843
Website
|
|
Structure based design of antiviral and antibacterial drugs; Inhibiting protein aggregation in disease; Computer modeling of immune system complexes and allergy inducing proteins; Comparing the physicochemical properties of allergenic proteins and their epitopes; sequence analysis and databases of allergens (SDAP) and viral proteins (Flavitrack)
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Schonbrunn, Agnes
|
Professor
Integrative Biology & Pharm
UT Health Science Center at Houston
|
Email
(713) 500-7470
Website
|
|
The mechanisms by which members of the seven-transmembrane domain (7TMD), G protein-coupled, receptor family respond to extracellular signals and the manner in which responsiveness is regulated.
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Scuseria, Gustavo E
|
Robert A. Welch Professor
Chemistry
Rice University
|
Email
713-348-4746
Website
|
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Theoretical chemistry, ab initio computational quantum chemistry, density functional theory, development of new methods for molecular electronic structure, and applications to nanostructures.
|
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Shi, Zheng-Zheng
|
Adjunct Assistant Professor
Radiology
The Methodist Hospital Research Institute
|
Email
713-441-8691
Website
|
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Shipley, Gregory
|
Ast Pr of Integrative Bio NTR
Integrative Biology & Pharm
UT Health Science Center at Houston
|
Email
(713) 500-7458
Website
|
|
Shipley, Nancy
|
Research Coordinator
HSC Core Labs
UT Health Science Center at Houston
|
Email
|
|
Siddik, Zahid H
|
Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
|
Email
713-792-7746
Website
|
|
Drug resistance, cell cycle, pharmacology, drug design
|
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Sifers, Richard
|
Associate Professor
Pathology
Baylor College of Medicine
|
Email
713-798-3169
Website
|
|
Cellular Glycobiology, Conformational Disease, Glycoprotein Folding, Quality Control, Oligosaccharides, Endoplasmic Reticulum, Conformational Disease, alpha1-Antitrypsin Deficiency, Glycobiology
|
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Silberg, Jonathan (Joff)
|
Assistant Professor
Biochemistry & Cell Biology
Rice University
|
Email
713-348-3849
Website
|
|
In our lab we are using a combination of biochemical, computational, and molecular biological methods to evolve folded and functional proteins with altered properties.
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Smith, Jack W.
|
Dean & Professor
School of Health Information Sciences
UT Health Science Center at Houston
|
Email
713-500-3925
Website
|
|
Artificial intelligence, modeling problem-solving in healthcare, implementation of decision support and tutoring systems, modeling complex human problem-solving, application of cognitive science to understanding, human-computer interaction
|
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Sokolov, Konstantin V.
|
Associate Professor
Imaging Physics
UT M. D. Anderson Cancer Center
|
Email
713-795-2656
Website
|
|
development on new optical imaging and spectroscopic modalities for pre-cancer detection and monitoring
|
|
Songyang, Zhou
|
Associate Professor
Biochemistry
Baylor College of Medicine
|
Email
713-798-5220
Website
|
|
Molecular Mechanisms of Signal Transduction; Proteomics and Protein-protein Interactions; Cell Senescence and Telomere Biology; Regulation of Cell Survival, Apoptosis, and Proliferation
|
|
Spudich, John
|
Professor/ R. Welch Dist Chr in Chemistry
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
|
Email
713-500-5473
Website
|
|
Structure and function of photoactive membrane receptors and signal transduction triggered by light; rhodopsins and related heptahelical receptors.
|
|
Stancel, George
|
Dr. John P. McGovern Professor and Dean
Graduate School of Biomedical Sciences
UT Health Science Center at Houston
|
Email
713-500-9880
Website
|
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Regulation of cell proliferation by estrogens; growth factors and cellular oncogenes as mediators of hormonally induced growth; regulation of transcription by estrogens; regulation of angiogenesis by estrogens and antiestrogens; regulation of uterine function by steroid hormones and antihormones; regulation of breast and uterine cancer cell proliferation by estrogens; developmental effects of exposure to environmental estrogens and other endocrine disruptors
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Standifer, Kelly
|
Associate Professor
Pharmacology
University of Houston
|
Email
713-743-1771
Website
|
|
ORL1 and m opioid receptor signaling; mechanisms of receptor cross-talk; opioid tolerance.
|
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Steffen, David
|
Dir Bioinf Rsrch Ctr
V.P. & Dean Of Research
Baylor College of Medicine
|
Email
713-798-2098
|
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Stephan, Clifford
|
Assistant Professor
Center for Clinical and Translational Science
UT Health Science Center at Houston
|
Email
|
|
Subramanian , Devika
|
Professor
Computer Science
Rice University
|
Email
713-348-5661
Website
|
|
Computational Biology, Conflict forecasting, Adaptive compilers, Machine learning, artificial intelligence, hybrid control, bioinformatics, cognitive science
|
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Thomas, Renard
|
Assistant Professor
Pharmaceutical Sciences
Texas Southern University
|
Email
|
|
Thompson, Edward Bradley
|
Professor and Chair
Biochemistry & Molecular Biology
UT Medical Branch at Galveston
|
Email
409-772-3367
|
|
This laboratory has a longstanding interest in the cellular and molecular actions of steroids, especially glucocorticoids and oxysterols.
|
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Tong, William Ping-Yiu
|
Professor
Experimental Diagnostic Imaging
UT M. D. Anderson Cancer Center
|
Email
713-563-0082
Website
|
|
Tsai, Ah-Lim
|
Professor
Medical School, Internal Medicine
UT Health Science Center at Houston
|
Email
713-500-6771
Website
|
|
Structure/Function and Reaction Mechanism of Important Metalloproteins
|
|
Tsai, Francis
|
Associate Professor
Biochemistry & Molecular Biology
Baylor College of Medicine
|
Email
713-798-8668
Website
|
|
Structure and function of macromolecular complexes and supramolecular assemblies involved in protein folding, transcriptional regulation and cellular signaling.
|
|
Tsai, Ming-Jer
|
Professor
Cell Biology
Baylor College of Medicine
|
Email
713-798-6253
Website
|
|
the role of transcription factors in gene regulation, development and diseases.
|
|
Tweardy, David
|
Professor
Medicine - Infectious Disease
Baylor College of Medicine
|
Email
Website
|
|
Impact of trauma and shock on host susceptibility to hospital-acquired infections; signal transduction events activated in cells and tissues by cytokines, focusing on signal tranducer and activator of transcription (STAT) 3
|
|
Vailas, Art
|
VC/VP, Research & Int Prop Mgt
Biology and Biochemistry
University of Houston
|
Email
713-743-9104
Website
|
|
My research program primarily focuses on the mechanisms associated with connective tissue plasticity. We have been interested in studying biological processes that impact extracellular matrix assembly, collagen maturation and turnover, and gene expression of various cytokines and macromolecules. Also, our work involves investigating collagen and proteoglycan interactions that impact the viscoelastic properties of dense fibrous connective tissues.
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Wang, Qinghua
|
Assistant Professor
Biochemistry and Molecular Biology
Baylor College of Medicine
|
Email
Website
|
|
Structural and Functional Study of Influenza Virus Hemagglutinin
|
|
Watowich, Stanley
|
Associate Professor
Biochemistry and Molecular Biology
UT Medical Branch at Galveston
|
Email
409-747-4749
Website
|
|
Dr. Watowich has long-standing interest in virus structure, function, host-responses to infection, and antiviral drug development. The laboratory has solved the crystal structures of individual non-structural and structural proteins from alphaviruses, and carried out biochemical and biophysical studies of flavivirus and alphavirus proteins. Structures of intact RNA viruses and their assembly mechanisms are studied by electron cryomicroscopy, image reconstruction, and biophysical techniques. Structure-based computational drug discovery, in vitro inhibition assays, and cell- based replication assays are used to develop antiviral agents.
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Webb, Paul
|
Research Scientist
Diabetes and Metabolic Disease
The Methodist Hospital Research Institute
|
Email
713-441-2516
Website
|
|
Nuclear receptors, genomics
|
|
Wensel, Theodore G
|
Professor
Biochemistry
Baylor College of Medicine
|
Email
713-798-6994
Website
|
|
Structure and Dynamics of Signal Transducing Membranes
|
|
West, Jennifer L.
|
Professor; Director, Inst of Biosciences & Bioengr
Bioengineering
Rice University
|
Email
713-348-5955
Website
|
|
Bioactive and biomimetic biomaterials; tissume engineering; nanotechnology; gene therapy; drug delivery
|
|
Widger, William
|
Associate Professor
Biology and Biochemistry
University of Houston
|
Email
(713) 743-8368
Website
|
|
Identifying unique drug target in e.coli; how and why ROS production occurs and how this is linked to the enzymatic mechanism of NUO; the structure/function studies of proteins involved in photosynthetic energy transduction
|
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Willerson, James T.
|
President of UTHSC at Houston, P E R Chr IM, A/W DisPs
Office Of The President
UT Health Science Center at Houston
|
Email
(713) 500-3000
Website
|
|
Wilson, John
|
Professor
Biochemistry
Baylor College of Medicine
|
Email
713-798-5760
Website
|
|
Targeted Genome Modification; Basis for instability of trinucleotide repeats, oligonucleotide-based therapy for diseases of the eye
|
|
Wilson, Lon J.
|
Professor
Chemistry
Rice University
|
Email
713-348-3476
Website
|
|
Metal ions in biological processes and their use in medicine
|
|
Wong, Stephen
|
Director
Center for Bioengineering and Informatics
The Methodist Hospital Research Institute
|
Email
713-441-5883
Website
|
|
Cancer and neuro drug discovery and repositioning, microenvironment modeling, image-based screening
|
|
Wood, Thomas
|
Professor
Biochemistry and Molecular Biology
UT Medical Branch at Galveston
|
Email
Website
|
|
Recombinant DNA Laboratory Core and Molecular Genomics Core
|
|
Wu, Kenneth
|
Professor & Director, Center for Vascular Biology
Internal Medicine, Hematology
UT Health Science Center at Houston
|
Email
(713) 500-6801
|
|
protein expression profiling
|
|
Wyne, Kittie
|
Neurology
The Methodist Hospital Research Institute
|
Email
713-441-0005
|
|
diabetes, obesity, and lipids
|
|
Xia, Xiaofeng
|
Instructor, Research Associate
Bioengineering and Informatics
The Methodist Hospital Research Institute
|
Email
713-441-8692
Website
|
|
Cancer stem cells, image-based screening
|
|
Xie, Huan
|
Assistant Professor
Pharmaceutical Sciences
Texas Southern University
|
Email
|
|
Nanoparticle-based drug formulation, drug delivery system, cancer therapy and diagnostics
|
|
Xu, Bo
|
Medicine
The Methodist Hospital Research Institute
|
Email
713-441-3996
|
|
DNA damages and cell cycle studies
|
|
Yung, W. K. Alfred
|
Professor, Chair
Neuro-Oncology
UT M. D. Anderson Cancer Center
|
Email
713-794-1285
Website
|
|
Cell cycle, pathologic neovascularization, gene therapy, antisense oligonucleotides
|
|
Zhang, Ming
|
Assistant Professor
Biostatistics & Applied Math
UT M. D. Anderson Cancer Center
|
Email
(713) 792-2607
Website
|
|
docking; computer-assisted drug design; protein folding; mathematical modeling; algorithms
|
|
Zhang, Shuxing
|
Assistant Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
|
Email
713-745-2958
Website
|
|
The fundamental foci of my research are to develop new computational methods and strategies that are urgently needed to efficiently deal with difficulties encountered in drug design and discovery, mainly in three areas: ligand-based drug design, structure-based drug design, and protein structure bioinformatics.
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|
Zhang, Wei
|
Associate Professor, Director of Cancer Genomics Core Laboratory
Pathology Research
UT M. D. Anderson Cancer Center
|
Email
713-745-1103
Website
|
|
Cancer Genomics by gene and protein expression profiling.
|
|
Zhao, Hong
|
Research Associate
Advanced Tissue and Cellular Imaging Laboratory
The Methodist Hospital Research Institute
|
Email
713-441-3557
Website
|
|
Breast cancer brain mets, image-based screening
|
|
Zhou, Xiaobo
|
Associate Professor
Bioengineering and Informatics
The Methodist Hospital Research Institute
|
Email
713-441-8692
Website
|
|
Systems biology, microenvironment modeling, image-based screening
|
|
Zygourakis, Kyriacos
|
A.J. Hartsook Professor | Department Chair
Chemical Engineering
Rice University
|
Email
713-348-5208
Website
|
|
Cellular and tissue engineering, Reaction engineering
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