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John S. Dunn, Sr. GCC for Magnetic Resonance
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Bankson, Jim  
Assistant Professor
Imaging Physics
UT M. D. Anderson Cancer Center
Email
Website
* Magnetic Resonance Imaging (MRI), phased arrays, parallel MRI and fast acquisition techniques
Braam, Janet  
Associate Professor
Biochemistry & Cell Biology
Rice University
Email
713-348-5287
Website
Regulation and functions of genes encoding calmodulin-related proteins and cell wall modifying enzymes of plants. Control of gene expression in response to environmental stimuli
Brennan, Richard G.  
Professor
Biochemistry & Molecular Biology
UT M. D. Anderson Cancer Center
Email
(713) 834-6390
Website
Multidrug resistance, protein-nucleic interaction, regulation of gene expression; oxidative stress responses; protein-ligand interaction, toxin-antitoxin structure and function; macromolecular crystallography
Budde, Ray  
Associate Professor
Neuro-Oncology Research
UT M. D. Anderson Cancer Center
Protein tyrosine kinase, enzyme inhibitors, catalysis, enzyme activation
Conboy, Claire  
Dow Chemicals
Dow Chemical
Email
979 238-4941
Fox, George E.  
Professor
Biology and Biochemistry
University of Houston
Email
713-743-8363
Website
Molecular Evolution, Bioinformatics, RNA structure and Evolution, Origin of Life, Environmental Monitoring, Molecular Biology, Array Hybridization; Protein folding, genomics, proteomics and systems biology
Gao, Xiaolian  
Professor
Chemistry
University of Houston
Email
713-743-2805
Website
Biophysical and organic chemistry; Research in the laboratory is at the interfaces of chemistry and biological sciences. Our work focuses on two areas: (1) Biological NMR of nucleic acids, proteins, and their complexes with ligand molecules. (2) Microarray BIOCHIP technologies in synthesis and applications.
Gelovani, Juri  
Radiology and Neurology
UT M. D. Anderson Cancer Center
Email
713-563-3343
Website
Gershon, Paul D.  
Assistant Professor
Biochemistry and Biophysics: IBT
TAMU
Email
713-677-7665
Website
mechanisms of mRNA 5' cap and poly(A) tail formation by vaccinia virus
Gorenstein, David G.  
Professor and Deputy Director
The Brown Foundation Institute of Molecular Medicine
UT Health Science Center at Houston
Email
713-500-2408
Website
Proteomics and nanomedicine for both diagnostics and therapeutics in both infectious diseases and cancer; structural biology, drug design, nucleic acid and protein chemistry
Higgins, Catherine  
Research Consortia
Gulf Coast Consortia
Email
713-348-4772
Hilser, Vincent  
Professor
Biochemistry and Molecular Biology
UT Medical Branch at Galveston
Email
409-747-6813
Website
Research in our lab is focused on the experimental characterization of conformational fluctuations, the development and refinement of a general ensemble-based model for fluctuations, and the projection of this thermodynamic model into genomic analysis. Our goals are to unify the description of protein behaviors in such a way as to understand their relationships at the phenomenological level, to codify these relationships in a simple structure-based model, and to apply our model to a number of experimental systems that can be used to test and refine our approach.
Iwahara, Junji  
Assistant Professor
Department of Biochemistry and Molecular Biology
UT Medical Branch at Galveston
Email
409-747-1403
Website
target search process whereby gene-regulatory proteins are able to efficiently and rapidly locate their specific DNA target sequence in a sea of non-specific DNA
Jackson, Ed  
Professor
Imaging Physics
UT M. D. Anderson Cancer Center
Email
Website
Jayaraman, Vasanthi  
Associate Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
Email
713-500-6236
Website
Structure and function; membrane bound proteins; ion channels
Kleerekoper, Quinn  
Research Fellow
Medical School
UT Health Science Center at Houston
Email
713-500-6119
Website
Ladbury, John  
Biochemistry and Molecular Biology
UT M. D. Anderson Cancer Center
Email
Website
Specificity in tyrosine kinase-mediated signal transduction
Legge, Glen  
Assistant Professor
Biology and Biochemistry
University of Houston
Email
713-743-8380
Website
structural biology to link the fields of biology and chemistry by an understanding of the molecular mechanisms of biological processes
Li, Renhao  
Assistant Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
Email
713-500-7233
Website
Molecular regulation and structural basis of transmembrane signaling
Luxon, Bruce  
Director, Professor
UTMB Bioinformatics Program, Dept. of Biochemistry and Molecular Biology
UT Medical Branch at Galveston
Email
409-747-6802
Website
Metabolomics studies related to diabetes, occupational exposure, cancer, addiction, and infectious disease. We specialize in integrating these data with parallel experiments including genomics, proteomics, kinomics, lipidomics, and LC/MS metabolomics.
MacKenzie , Kevin R  
Assistant Professor
Biochemistry & Cell Biology
Rice University
Email
713-348-2228
Website
Structure and stability of membrane proteins
Matsuda, Seiichi  
Professor
Chemistry
Rice University
Email
713-348-6158
Website
Recombinant biosynthetic approaches to natural product biosynthesis. Directed evolution and DNA shuffling to generate new oxidosqualene cyclases. Metabolic engineering to produce terpenes.
McMurray, John  
Associate Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
Email
713-745-3763
Website
Bio-organic chemistry, peptide and peptidomimetic chemistry, structure-guided drug design, protein-protein interaction, enzyme inhibitor design. Our work concerns the design of inhibitors of important protein-protein interactions with the overall goal of developing chemotherapeutic agents as well as reagents to probe signal transduction mechanisms. Our current targets are the STAT (signal transduction and activator of transcription) proteins. Our strategy is to find high affinity peptides to inhibit target protein-protein interactions, determine which parts of the peptide contributes to binding energy, determine the bound conformation, then combine this information to develop small molecule inhibitors that mimic the action of the peptide. Another strategy is screening a small molecule library to find leads.
Moran, Sean  
Bio NMR Facility Manager; NMR Facility Manager
RE Smalley Inst Nanoscale Sci & Tec
Rice University
Email
713-348-4255
Morrisett , Joel  
Professor
Medicine Athero & Lipo
Baylor College of Medicine
Email
713-798-4164
Website
Imaging, Genomics, and Proteomics of Human Atherosclerosis; elucidating the mechanism(s) whereby Lp[a] exerts its atherogenic effects; The apo[a] protein; Peptide segmenets found in the proline-rich motif of cytokine receptors are under study using the techniques of molecular modeling, circular dichroism, and nuclear magnetic resonance spetroscopy.
Narayana, Ponnada  
Professor of Diagnostic and Interventional Imaging; Director of MR Research
Radiology
UT Health Science Center at Houston
Email
Website
Nikonowicz, Edward  
Associate Professor
Biochemistry & Cell Biology
Rice University
Email
713-348-4912
Website
RNA-Protein biochemistry, structure-function relationships in nucleic acid systems; In addition to NMR spectroscopy, we use biochemical, computational, and optical methods to investigate the kinetic, motional, and structural properties of the component molecules; The interaction of primary ribosomal proteins with their RNA targets; Post-transcriptional modification of tRNA.
Olson, John Steve  
Dorothy/Ralph Looney Professor
Biochemistry & Cell Biology
Rice University
Email
713-348-4762
Website
Application of rapid reaction techniques to biophysical and biochemical problems; protein engineering by recombinant DNA technology; structural (X-ray, IR, and NMR) and functional studies of ligand binding to hemoglobins, myoglobins, and model heme compounds; design of heme protein-based blood substitutes; red blood cell physiology; biosynthesis of heme and hemoglobin; gas transport and exchange in capillaries.
Parry, Ronald J.  
Professor
Chemistry
Rice University
Email
713-348-2446
Website
Biosynthesis of natural products and the mechanisms of enzymatic reactions; Investigations of the biosynthesis of the phytotoxin coronatine, the antibiotic aristeromycin, and the antitumor agents sparsomycin and valanimycin.
Pautler, Robia  
Assistant Professor
Neuroscience, Radiology
Baylor College of Medicine
Email
Website
Dr. Pautler develops and applies methodologies that permit high- resolution images of the structure and function of the brain in intact, living animals.
Penczek, Pawel  
Associate Professor
Biochemistry and Molecular Biology
UT Health Science Center at Houston
Email
713-500-5416
Website
We are interested in the determination of three-dimensional structures of large macromolecular complexes with low or non-existing symmetry in single-particle form using stain and cryo-electron microscopy (cryo-EM) and computer image processing techniques.
Priebe, Waldemar  
Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
Email
713-792-3777
Website
Drug Design, Kinase Inhibitors, DNA Binding Agents, Drug Resistance, Hypoxia
Putkey, John  
Professor
Medical School
UT Health Science Center at Houston
Email
713-500-6061
Website
My laboratory applies a synergistic blend of molecular and structural biology to study the molecular anatomy of calcium binding proteins; The mechanisms of regulation of calmodulin activity by post-translational modification and modulation of calmodulin binding to target proteins; Exploring the molecular mechanism of regulation of cardiac muscle contraction by calcium binding to cardiac troponin C, and how cardiotonic drugs lead to an increased efficiency of cardiac muscle contraction; Using NMR to reveal the strucutral basis behind why mutations in the extracelluar matix protein COMP lead to skeletal dysplasias and dwarfing syndromes.
Rajarathnam, Krishna  
Assistant Professor
Neuroscience and Cell Biology
UT Medical Branch at Galveston
Email
409-772-2238
Website
Exploiting the structural elements of chemokines and their receptors towards rational design of therapeutics. We are interested in understanding the molecular basis of ligand-receptor interaction.
Ridge, Kevin  
Associate Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
Email
(713) 500-5908
Website
Dynamic aspects of integral membrane protein structure, development and application of general approaches for the large-scale expression and purification of GPCR's
Roebuck, Joseph  
Chief of Experimental Clinical Imaging
Radiology
UT Medical Branch at Galveston
Email
Ruan, Kehe  
Professor
Pharmacological and Pharmaceutical Sciences
University of Houston
Email
713-743-1771
Website
Using small compounds/peptide/protein/gene/cells to develop novel approaches targeting Vascular Diseases (such as stroke and heart diseases), cancers and tissue regenerations
Sankaranarayanapillai, Madhuri  
Research Scientist
Experimental Imaging
UT M. D. Anderson Cancer Center
Email
MRS of cells and tissues, metabolomics
Schumacher, Maria A.  
Assistant Professor
Biochemistry & Molecular Biology
UT M. D. Anderson Cancer Center
Email
(713) 834-6392
Website
Structural biology; crystallography; DNA partition/segregation; transcription regulation; nucleic acid-binding proteins
Serysheva, Irina  
Associate Professor
Biochemistry & Molecular Biology
UT Health Science Center at Houston
Email
713-500-5523
Website
Molecular mechanisms underlying ion transport into and out of the cell across the surface membrane, or between different intracellular compartments using structure-function studies of membrane proteins and the macromolecular assemblies they form
Shamoo , Yousif  
Associate Professor
Biochemistry & Cell Biology
Rice University
Email
713-348-5493
Website
sequence-specic RNA recognition, DNA replication and molecular evolution of microbial populations
Silberg, Jonathan (Joff)  
Assistant Professor
Biochemistry & Cell Biology
Rice University
Email
713-348-3849
Website
In our lab we are using a combination of biochemical, computational, and molecular biological methods to evolve folded and functional proteins with altered properties.
Spudich, John  
Professor/ R. Welch Dist Chr in Chemistry
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
Email
713-500-5473
Website
Structure and function of photoactive membrane receptors and signal transduction triggered by light; rhodopsins and related heptahelical receptors.
Strobel, Henry  
Professor/Assoc. Dean Faculty Affairs/Asst. Dean Student Affairs
Medical School
UT Health Science Center at Houston
Email
713-500-6078
Website
Gene expression, Gender-Specific CYP3A Expression in Rodents, Identification and Characterization of Novel CYP3As in Primates
Thiviyanathan, Varatharasa  
Research Scientist
Molecular Medicine
UT Health Science Center at Houston
Email
713-500-2232
Tsai, Ah-Lim  
Professor
Medical School, Internal Medicine
UT Health Science Center at Houston
Email
713-500-6771
Website
Structure/Function and Reaction Mechanism of Important Metalloproteins
Veeraraghavan, Sudha  
Research Assistant Professor
Biochemistry and Molecular Biology
UT Health Science Center at Houston
Email
713-500-6089
Website
molecular basis of cellular function, growth, and apoptosis
Volk, David  
Research Scientist
Molecular Medicine
UT Health Science Center at Houston
Email
Website
human health and structural biology
Wilson, Bill  
Biochemistry and Cell Biology
Rice University
Email
713-348-4914
Website
Xia, Youlin  
Research Associate
Chemistry
University of Houston
Email
713-747-9267
Website
Zheng, Lei  
Assistant Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
Email
713-500-6083
Website
Maintaining ion homeostasis across the cell membrane is fundamental to normal cell function. The research of our lab focuses on structure, function and regulation of ion transport proteins by using a combination of biochemical and biophysical approaches, primarily X-ray crystallography.
 
   

Gulf Coast Consortia Participating Institutions
Mailing Addresses

Baylor College of Medicine
One Baylor Plaza
Houston, TX 77030
713-798-4951
Rice University
P.O. Box 1892
Houston, Texas 77251-1892
713-348-0000

UT Health Science Center at Houston
7000 Fannin Street
Houston, Texas 77030
713-500-4472

UT M. D. Anderson Cancer Center
1515 Holcombe Blvd.
Houston, TX 77030
713-792-6161
UT Medical Branch at Galveston
301 University Blvd.
Galveston, Texas 77555
409-772-1011
University of Houston
4800 Calhoun Rd.
Houston, TX 77004
713-743-2255

 

 

 

The Gulf Coast Consortia
The Gulf Coast Consortia for Bioinformatics

Gulf Coast Consortia  ll  c/o Rice University  ll  6100 Main Street, MS-141
Houston, TX 77005
phone 713-348-4752

The Gulf Coast Consortia for Bioinformatics The Gulf Coast Consortia for Bioinformatics The Gulf Coast Consortia for Bioinformatics
Baylor College of Medicine UTMB Internal Medicine Rice University University of Houston MD Anderson Cancer Center UT-Houston