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GCC Magnetic Resonance Directory
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Bankson, Jim
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Assistant Professor
Imaging Physics
UT M. D. Anderson Cancer Center
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Email
Website
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* Magnetic Resonance Imaging (MRI), phased arrays, parallel MRI and fast acquisition techniques
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Braam, Janet
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Associate Professor
Biochemistry & Cell Biology
Rice University
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Email
713-348-5287
Website
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Regulation and functions of genes encoding calmodulin-related proteins and cell wall modifying enzymes of plants. Control of gene expression in response to environmental stimuli
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Brennan, Richard G.
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Professor
Biochemistry & Molecular Biology
UT M. D. Anderson Cancer Center
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Email
(713) 834-6390
Website
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Multidrug resistance, protein-nucleic interaction, regulation of gene expression; oxidative stress responses; protein-ligand interaction, toxin-antitoxin structure and function; macromolecular crystallography
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Budde, Ray
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Associate Professor
Neuro-Oncology Research
UT M. D. Anderson Cancer Center
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Protein tyrosine kinase, enzyme inhibitors, catalysis, enzyme activation
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Conboy, Claire
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Dow Chemicals
Dow Chemical
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Email
979 238-4941
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Fox, George E.
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Professor
Biology and Biochemistry
University of Houston
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Email
713-743-8363
Website
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Molecular Evolution, Bioinformatics, RNA structure and Evolution, Origin of Life, Environmental Monitoring, Molecular Biology, Array Hybridization; Protein folding, genomics, proteomics and systems biology
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Gao, Xiaolian
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Professor
Chemistry
University of Houston
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Email
713-743-2805
Website
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Biophysical and organic chemistry; Research in the laboratory is at the interfaces of chemistry and biological sciences. Our work focuses on two areas: (1) Biological NMR of nucleic acids, proteins, and their complexes with ligand molecules. (2) Microarray BIOCHIP technologies in synthesis and applications.
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Gelovani, Juri
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Radiology and Neurology
UT M. D. Anderson Cancer Center
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Email
713-563-3343
Website
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Gershon, Paul D.
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Assistant Professor
Biochemistry and Biophysics: IBT
TAMU
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Email
713-677-7665
Website
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mechanisms of mRNA 5' cap and poly(A) tail formation by vaccinia virus
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Gorenstein, David G.
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Professor and Deputy Director
The Brown Foundation Institute of Molecular Medicine
UT Health Science Center at Houston
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Email
713-500-2408
Website
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Proteomics and nanomedicine for both diagnostics and therapeutics in both infectious diseases and cancer; structural biology, drug design, nucleic acid and protein chemistry
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Higgins, Catherine
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Research Consortia
Gulf Coast Consortia
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Email
713-348-4772
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Hilser, Vincent
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Professor
Biochemistry and Molecular Biology
UT Medical Branch at Galveston
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Email
409-747-6813
Website
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Research in our lab is focused on the experimental characterization of conformational fluctuations, the development and refinement of a general ensemble-based model for fluctuations, and the projection of this thermodynamic model into genomic analysis. Our goals are to unify the description of protein behaviors in such a way as to understand their relationships at the phenomenological level, to codify these relationships in a simple structure-based model, and to apply our model to a number of experimental systems that can be used to test and refine our approach.
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Iwahara, Junji
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Assistant Professor
Department of Biochemistry and Molecular Biology
UT Medical Branch at Galveston
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Email
409-747-1403
Website
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target search process whereby gene-regulatory proteins are able to efficiently and rapidly locate their specific DNA target sequence in a sea of non-specific DNA
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Jackson, Ed
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Professor
Imaging Physics
UT M. D. Anderson Cancer Center
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Email
Website
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Jayaraman, Vasanthi
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Associate Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
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Email
713-500-6236
Website
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Structure and function; membrane bound proteins; ion channels
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Kleerekoper, Quinn
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Research Fellow
Medical School
UT Health Science Center at Houston
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Email
713-500-6119
Website
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Ladbury, John
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Biochemistry and Molecular Biology
UT M. D. Anderson Cancer Center
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Email
Website
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Specificity in tyrosine kinase-mediated signal transduction
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Legge, Glen
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Assistant Professor
Biology and Biochemistry
University of Houston
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Email
713-743-8380
Website
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structural biology to link the fields of biology and chemistry by an understanding of the molecular mechanisms of biological processes
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Li, Renhao
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Assistant Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
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Email
713-500-7233
Website
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Molecular regulation and structural basis of transmembrane signaling
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Luxon, Bruce
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Director, Professor
UTMB Bioinformatics Program, Dept. of Biochemistry and Molecular Biology
UT Medical Branch at Galveston
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Email
409-747-6802
Website
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Metabolomics studies related to diabetes, occupational exposure, cancer, addiction, and infectious disease. We specialize in integrating these data with parallel experiments including genomics, proteomics, kinomics, lipidomics, and LC/MS metabolomics.
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MacKenzie , Kevin R
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Assistant Professor
Biochemistry & Cell Biology
Rice University
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Email
713-348-2228
Website
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Structure and stability of membrane proteins
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Matsuda, Seiichi
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Professor
Chemistry
Rice University
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Email
713-348-6158
Website
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Recombinant biosynthetic approaches to natural product biosynthesis. Directed evolution and DNA shuffling to generate new oxidosqualene cyclases. Metabolic engineering to produce terpenes.
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McMurray, John
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Associate Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
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Email
713-745-3763
Website
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Bio-organic chemistry, peptide and peptidomimetic chemistry, structure-guided drug design, protein-protein interaction, enzyme inhibitor design. Our work concerns the design of inhibitors of important protein-protein interactions with the overall goal of developing chemotherapeutic agents as well as reagents to probe signal transduction mechanisms. Our current targets are the STAT (signal transduction and activator of transcription) proteins. Our strategy is to find high affinity peptides to inhibit target protein-protein interactions, determine which parts of the peptide contributes to binding energy, determine the bound conformation, then combine this information to develop small molecule inhibitors that mimic the action of the peptide. Another strategy is screening a small molecule library to find leads.
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Moran, Sean
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Bio NMR Facility Manager; NMR Facility Manager
RE Smalley Inst Nanoscale Sci & Tec
Rice University
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Email
713-348-4255
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Morrisett , Joel
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Professor
Medicine Athero & Lipo
Baylor College of Medicine
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Email
713-798-4164
Website
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Imaging, Genomics, and Proteomics of Human Atherosclerosis; elucidating the mechanism(s) whereby Lp[a] exerts its atherogenic effects; The apo[a] protein; Peptide segmenets found in the proline-rich motif of cytokine receptors are under study using the techniques of molecular modeling, circular dichroism, and nuclear magnetic resonance spetroscopy.
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Narayana, Ponnada
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Professor of Diagnostic and Interventional Imaging; Director of MR Research
Radiology
UT Health Science Center at Houston
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Email
Website
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Nikonowicz, Edward
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Associate Professor
Biochemistry & Cell Biology
Rice University
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Email
713-348-4912
Website
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RNA-Protein biochemistry, structure-function relationships in nucleic acid systems; In addition to NMR spectroscopy, we use biochemical, computational, and optical methods to investigate the kinetic, motional, and structural properties of the component molecules; The interaction of primary ribosomal proteins with their RNA targets; Post-transcriptional modification of tRNA.
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Olson, John Steve
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Dorothy/Ralph Looney Professor
Biochemistry & Cell Biology
Rice University
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Email
713-348-4762
Website
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Application of rapid reaction techniques to biophysical and biochemical problems; protein engineering by recombinant DNA technology; structural (X-ray, IR, and NMR) and functional studies of ligand binding to hemoglobins, myoglobins, and model heme compounds; design of heme protein-based blood substitutes; red blood cell physiology; biosynthesis of heme and hemoglobin; gas transport and exchange in capillaries.
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Parry, Ronald J.
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Professor
Chemistry
Rice University
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Email
713-348-2446
Website
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Biosynthesis of natural products and the mechanisms of enzymatic reactions; Investigations of the biosynthesis of the phytotoxin coronatine, the antibiotic aristeromycin, and the antitumor agents sparsomycin and valanimycin.
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Pautler, Robia
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Assistant Professor
Neuroscience, Radiology
Baylor College of Medicine
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Email
Website
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Dr. Pautler develops and applies methodologies that permit high- resolution images of the structure and function of the brain in intact, living animals.
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Penczek, Pawel
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Associate Professor
Biochemistry and Molecular Biology
UT Health Science Center at Houston
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Email
713-500-5416
Website
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We are interested in the determination of three-dimensional structures of large macromolecular complexes with low or non-existing symmetry in single-particle form using stain and cryo-electron microscopy (cryo-EM) and computer image processing techniques.
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Priebe, Waldemar
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Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
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Email
713-792-3777
Website
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Drug Design, Kinase Inhibitors, DNA Binding Agents, Drug Resistance, Hypoxia
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Putkey, John
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Professor
Medical School
UT Health Science Center at Houston
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Email
713-500-6061
Website
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My laboratory applies a synergistic blend of molecular and structural biology to study the molecular anatomy of calcium binding proteins; The mechanisms of regulation of calmodulin activity by post-translational modification and modulation of calmodulin binding to target proteins; Exploring the molecular mechanism of regulation of cardiac muscle contraction by calcium binding to cardiac troponin C, and how cardiotonic drugs lead to an increased efficiency of cardiac muscle contraction; Using NMR to reveal the strucutral basis behind why mutations in the extracelluar matix protein COMP lead to skeletal dysplasias and dwarfing syndromes.
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Rajarathnam, Krishna
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Assistant Professor
Neuroscience and Cell Biology
UT Medical Branch at Galveston
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Email
409-772-2238
Website
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Exploiting the structural elements of chemokines and their receptors towards rational design of therapeutics. We are interested in understanding the molecular basis of ligand-receptor interaction.
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Ridge, Kevin
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Associate Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
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Email
(713) 500-5908
Website
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Dynamic aspects of integral membrane protein structure, development and application of general approaches for the large-scale expression and purification of GPCR's
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Roebuck, Joseph
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Chief of Experimental Clinical Imaging
Radiology
UT Medical Branch at Galveston
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Email
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Ruan, Kehe
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Professor
Pharmacological and Pharmaceutical Sciences
University of Houston
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Email
713-743-1771
Website
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Using small compounds/peptide/protein/gene/cells to develop novel approaches targeting Vascular Diseases (such as stroke and heart diseases), cancers and tissue regenerations
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Sankaranarayanapillai, Madhuri
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Research Scientist
Experimental Imaging
UT M. D. Anderson Cancer Center
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Email
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MRS of cells and tissues, metabolomics
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Schumacher, Maria A.
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Assistant Professor
Biochemistry & Molecular Biology
UT M. D. Anderson Cancer Center
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Email
(713) 834-6392
Website
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Structural biology; crystallography; DNA partition/segregation; transcription regulation; nucleic acid-binding proteins
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Serysheva, Irina
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Associate Professor
Biochemistry & Molecular Biology
UT Health Science Center at Houston
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Email
713-500-5523
Website
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Molecular mechanisms underlying ion transport into and out of the cell across the surface membrane, or between different intracellular compartments using structure-function studies of membrane proteins and the macromolecular assemblies they form
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Shamoo , Yousif
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Associate Professor
Biochemistry & Cell Biology
Rice University
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Email
713-348-5493
Website
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sequence-specic RNA recognition, DNA replication and molecular evolution of microbial populations
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Silberg, Jonathan (Joff)
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Assistant Professor
Biochemistry & Cell Biology
Rice University
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Email
713-348-3849
Website
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In our lab we are using a combination of biochemical, computational, and molecular biological methods to evolve folded and functional proteins with altered properties.
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Spudich, John
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Professor/ R. Welch Dist Chr in Chemistry
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
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Email
713-500-5473
Website
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Structure and function of photoactive membrane receptors and signal transduction triggered by light; rhodopsins and related heptahelical receptors.
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Strobel, Henry
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Professor/Assoc. Dean Faculty Affairs/Asst. Dean Student Affairs
Medical School
UT Health Science Center at Houston
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Email
713-500-6078
Website
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Gene expression, Gender-Specific CYP3A Expression in Rodents, Identification and Characterization of Novel CYP3As in Primates
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Thiviyanathan, Varatharasa
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Research Scientist
Molecular Medicine
UT Health Science Center at Houston
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Email
713-500-2232
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Tsai, Ah-Lim
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Professor
Medical School, Internal Medicine
UT Health Science Center at Houston
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Email
713-500-6771
Website
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Structure/Function and Reaction Mechanism of Important Metalloproteins
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Veeraraghavan, Sudha
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Research Assistant Professor
Biochemistry and Molecular Biology
UT Health Science Center at Houston
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Email
713-500-6089
Website
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molecular basis of cellular function, growth, and apoptosis
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Volk, David
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Research Scientist
Molecular Medicine
UT Health Science Center at Houston
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Email
Website
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human health and structural biology
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Wilson, Bill
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Biochemistry and Cell Biology
Rice University
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Email
713-348-4914
Website
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Xia, Youlin
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Research Associate
Chemistry
University of Houston
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Email
713-747-9267
Website
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Zheng, Lei
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Assistant Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
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Email
713-500-6083
Website
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Maintaining ion homeostasis across the cell membrane is fundamental to normal cell function. The research of our lab focuses on structure, function and regulation of ion transport proteins by using a combination of biochemical and biophysical approaches, primarily X-ray crystallography.
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