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Keck Center For Interdisciplinary Bioscience Training Directory
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Advincula, Rigoberto
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Associate Professor
Chemistry
University of Houston
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Email
(713) 743-1760
Website
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Polymer and organic ultrathin films. We investigate the design and synthesis of organic macromolecules and oligomers capable of controlled-assembly or self-organization as ultrathin films. This includes functional amphiphile synthesis, polymerization on surfaces, network formation, and preparation of ð-electron conjugated polymers.
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Almeida, Jonas
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Professor
Biostatistics & Applied Math
UT M. D. Anderson Cancer Center
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Email
713/792-9875
Website
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Systems biology, Biomarker identification, Drug / target discovery, Statistical mechanics. Professor Almeida's research interests are directed towards the computational and mathematical tools and mathematical formalisms needed to tackle the twin challenges of identifying biomarkers and targets for drug discovery.
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Annapragada, Ananth
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Associate Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3982
Website
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Targeted drug delivery; computational methods in biomedicine. My research interests are in the area of novel drug delivery systems and MEMS technology applied to drug delivery. Current projects include the development of engineered porous particles for aerosol drug delivery, the simulation of particle flow in pulmonary airways, and targeted drug delivery.
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Aoki, Noriaki
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Assistant Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3930
Website
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Decision science/clinical decision support; Data mining/ modeling in healthcare; Healthcare technology assessment; Clinical informatics in extreme environments
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Arap, Wadih
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Professor
Genitourinary Medical Oncology
UT M. D. Anderson Cancer Center
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Email
713/792-3871
Website
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Pathologic neovascularization, angiogenesis inhibitors, biological tumor markers, drug delivery system. Our research is aimed at targeting blood vessels for delivery of diagnostic and therapeutic agents by using probes that can bind to specific addresses in selective vascular beds.
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Atmar, Robert L.
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Associate Professor of Medicine and of Molecular Virology and Microbiology
Infectious Diseases
Baylor College of Medicine
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Email
713-798-6849
Website
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My research interests are in two main areas. The first is in the study of respiratory viruses, including their epidemiology, pathogenesis, diagnosis, treatment and prevention. My second area of interest is in enteric viruses and environmental virology, with a special emphasis on noroviruses. We use Norwalk virus as a model virus for our studies, both in the laboratory and in an experimental human infection model. I am interested in the development and application of diagnostic approaches to detect enteric viral pathogens in waters, shellfish, and other foods.
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Azevedo, Ricardo
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Assistant Professor
Biology and Biochemistry
University of Houston
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Email
713-743-2636
Website
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My aim is to understand how phenotypic variation is generated and how it influences the course of evolution. To answer these questions I am employing a variety of approaches from developmental biology, genetics, comparative analysis, computational biology and mathematical modelling. As an experimental system I use the nematode worm Caenorhabditis elegans and other closely related species. I am particularly interested in how cell lineage variability evolves in different groups of animals.
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Baggerly, Keith
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Assistant Professor
Biostatistics
UT M. D. Anderson Cancer Center
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Email
713-745-5994
Website
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Proteomics (mass spectrometry); microarrays; serial analysis of gene expression; My research focuses on the processing of high-throughput bioinformatics experiments.
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Barrett, Alan
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Professor
Pathology
UT Medical Branch at Galveston
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Email
(409) 772-6662
Website
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My research program focuses on two groups of viruses: flaviviruses and bunyaviruses. Both groups contain viruses that are transmitted by arthropods, such as mosquitoes and ticks, and are given the general term of
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Barry, Michael
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Associate Professor
Molecular and Human Genetics, Immunology
Baylor College of Medicine
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Email
713-798-5959
Department
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We are interested in testing the ability of genetic vaccines to combat pathogens that have evolved to escape the immune system. To do this, we are taking advantage of the fact that genetic vaccines are simple plasmids and that these can be easily manipulated by recombinant techniques to improve the immunogenicity of vaccine antigens.
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Bartel, Bonnie
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Associate Professor
Biochemistry & Cell Biology
Rice University
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Email
713-348-5602 /
Website
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Genetic analyses of the roles of auxin conjugates and indole-3-butyric acid in auxin homeostasis, auxin response mutants, forward and reverse genetic approaches to understanding peroxisome biogenesis and plant peroxisomal functions, functional genomics in understanding how and why plants synthesize diverse triterpenoids, and the roles and targets of microRNAs in plants
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Bast, Robert
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Professor
Experimental Therapeutics; Translational Research
UT M. D. Anderson Cancer Center
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Email
713-792-7743
Website
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Signal transduction, ovarian neoplasms, breast neoplasms, biological markers, tumor suppressor genes. Our laboratory has focused on the biology, detection, prevention, and treatment of epithelial ovarian and breast cancers. Over the past decade, we have found that ovarian cancer is generally a clonal disease and have focused our attention on molecular changes that occur during malignant transformation.
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Bear, John
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Dean, College of Natural Sciences and Mathematics
Chemistry
University of Houston
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Email
713-743-2618
Website
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Over the past few years our research has been aimed at understanding structure reactivity relationships of several group VIII-B dinuclear transition metal complexes and to use this information to control the chemical and electrochemical reactivity at the metal centers.
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Beckingham, Kate
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Professor
Biochemistry & Cell Biology
Rice University
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Email
713-348-4016
Website
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Calcium signaling in Drosophila; Gravity sensing in Drosophila; Analysis of developmental processes mediated by the ubiquitous calcium sensor calmodulin and investigation of a new testis-specific calcium sensor protein which we have identified and termed Androcam. To identify the pathways involved in gravitational responses, we are isolating mutants of Drosophila melanogaster that show aberrant gravitaxic behavior.
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Bennett, George N.
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Professor/ Department Chair
Biochemistry and Cell Biology
Rice University
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Email
713-348-4920
Website
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Molecular biology of prokaryotes. Metabolic engineering: Current work is directed toward compounds derived from central metablism intermediates such as succinate, esters, solvents and other small molecules. Mathematical approaches, bioreactor studies and genetic strategies are used to guide experiments. Gene regulation: As part of efforts to understand the regulation of metabolic and environmental response functions, natural and constructed expression systems are studied.
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Bernstam, Elmer V.
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Associate Professor of Health Informatics
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3927
Website
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Shareable executable clinical practice guidelines; consumer health informatics; MEDLINE searching (Medline Query-By-Example), informatics in clinical and translational research
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Berry, Donald
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Chair
Biostatistics
UT M. D. Anderson Cancer Center
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Email
713-794-4141
Website
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Clinical trials, statistical data interpretation, genetic predisposition to disease, biological markers
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Bittner, Eric
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Associate Professor
Chemistry
University of Houston
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Email
(713) 743-2775
Website
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Theoretical chemical physics. My research in the area of quantum dynamics is primarily focused upon understanding how motions in the condensed phase influence the dynamics of an imbedded quantum mechanical system.
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Blaney, Susan
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Associate Professor
Pediatrics-Hema & Oncology
Baylor College of Medicine
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Email
832-822-1482
BlaneyHome Page
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Neuro-Oncology and Clinical Pharmacology Programs. A primary focus of my research is the development of new drugs for the treatment of central nervous system tumors in children with a particular emphasis on the development of new agents for intrathecal administration.
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Boerwinkle, Eric
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Professor
School of Public Health
UT Health Science Center at Houston
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Email
713-500-9800
Website
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Human genetics; epidemiology; heart disease; lipid metabolism; apolipoprotein genes; DNA variation. The objective of research in this laboratory is to understand the role of individual genes in complex physiological systems characterized by gene-gene and gene-environment interactions. The model system used is lipid metabolism and its contribution to atherosclerosis. This laboratory also has experience in typing and characterizing DNA variation in highly repetitive and polymorphic VNTR loci.
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Bolen , D. Wayne
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Professor
Human Biological Chem & Genetics (HBC&G)
UT Medical Branch at Galveston
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Email
409-772-0754
Website
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The research in my laboratory involves two closely related areas of protein physical chemistry: (1) the physico-chemical bases of the ability of naturally occurring protecting osmolytes to stabilize proteins, and (2) the thermodynamics of denaturant-induced transitions of proteins.
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Borcea, Liliana
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Associate Professor
Comp & Applied Mathematics
Rice University
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Email
713-348-5723
Website
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Inverse scattering in random media, Electro-magnetic inverse problems, Study of physical media: effective properties of composite materials, transport in heterogeneous media, Transport in high contrast media, flow in porous media, percolation, Magnetorheological elastomers and fluids
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Boriek, Aladin
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Associate Professor
Medicine Pulmonary
Baylor College of Medicine
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Email
713-798-6091
Website
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Modeling diaphragm mechanics; Modeling force transmission based on fiber architecture of skeletal muscles; Modeling force transmission based on the structural arrangements of cytoskeletal proteins in skeletal muscles. Mechanical signal transduction. We are interested in signal transduction in skeletal and smooth muscles in response to mechanical forces.
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Bornmann, William
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Professor, Synthetic Chemistry
Experimental Therapeutics
UT M. D. Anderson Cancer Center
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Email
713-563-0081
Website
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Synthesis, purification and characterization of various novel biologically active molecules that can be developed into new optical, PET and MRI/MRSI imaging probes; Synthesis of precursor molecules for radiolabeling, paramagnetic and fluorescent labeling.
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Bourne, Nigel
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Associate Professor, Pediatrics
Microbiology and Immunology
UT Medical Branch at Galveston
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Email
409-747-8144
Website
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Structural biology of viral infection
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Brandt, Michael
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Associate Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3463
Website
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Biomedical engineering; computational biomedicine; neuroimaging
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Braun, Werner
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Professor
Human Biological Chem & Genetics (HBC&G)
UT Medical Branch at Galveston
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Email
409-747-6810
Website
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The challenge in the post genomic era is to make full use of the vast genomic data in understanding the molecular mechanism of the function of proteins.
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Briggs, James
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Associate Professor
Biology and Biochemistry
University of Houston
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Email
713-743-8366
Website
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Computational studies of protein structure and function; Our research is focused on computational studies of protein structure and function, inhibitor design, investigations of possible inhibitor resistance pathways, and development of methods for the above project areas. Targets for these studies include those important in the treatment of AIDS, cancer, bacterial infections, and other disease states. In addition, we work on inhibitors to aid in biowarfare defense (botulinum neurotoxins, anthrax toxin).
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Brinkley, William (Bill)
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VP Dean Of Grad Sch
Corporate Officers-Molecular and Celular Biology
Baylor College of Medicine
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Email
713-798-5263
Website
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We seek to understand the molecular basis of errors and defects in the nucleus and mitotic apparatus (MA) that cause aneuploidy. Our research utilizes molecular biology and genetic approaches combined with digital image analysis at the light and electron microscopy levels to analyze normal and defective features of chromosome condensation, attachment and alignment on the spindle and movements during mitosis in normal and neoplastic cells.
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Brownell, William
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Professor
Otorhinolaryngology
Baylor College of Medicine
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Email
713-798-8540
Website
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Fundamental mechanisms of hearing and biophysics of electromobility
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Bujalowski , Wlodzimierz
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Professor
Human Biological Chem & Genetics (HBC&G)
UT Medical Branch at Galveston
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Email
409-772-5634
Website
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We have a long-term interest in quantitative understanding of the structure-function relationships in protein-nucleic acid interactions in solution.Such understanding can be achieved through rigorous thermodynamic, kinetic, and structural (spectroscopic) studies of both macromolecules and their relevant complexes.
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Butel, Janet
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Distinguished Service Professor and Head
Molecular Virology & Microbiology
Baylor College of Medicine
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Email
713-798-4443
Website
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We are interested in small DNA tumor viruses called polyomaviruses, the structure and function of the viral oncogene proteins, and mechanisms of tumor development.
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Byrne, John
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Professor and Chairman
Medical School
UT Health Science Center at Houston
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Email
713-500-5602
Website
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Dr. Byrne's research interests involve elucidating the neuronal and molecular mechanisms underlying learning and memory
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Cai, Chengzhi
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Assistant Professor
Chemistry
University of Houston
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Email
(713) 743-2710
Website
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supramolecular nanostructures
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Cavasotto, Claudio
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Assistant Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3934
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Computational Biochemistry & Biophysics, and Drug Discovery: Computer-aided drug discovery; protein modeling; study of protein interaction and function; chemoinformatics; simulation theory, force-field development. Studied biomolecular systems include, but not limited to, hormone nuclear receptors, protein kinases and GPCRs.
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Chen, Xiaomin
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Assistant Professor
Biochemistry & Molecular Biology
UT M. D. Anderson Cancer Center
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Email
713-834-6279
Website
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X-ray crystallography, macromolecular interactions, signal transduction, transcription regulation, apoptosis
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Cheng, Xiaodong
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Associate Professor
Pharmacology
UT Medical Branch at Galveston
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Email
409-772-9656
Website
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Mitogen-activated protein kinases
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Chiu, Wah
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Professor
Biochemistry
Baylor College of Medicine
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Email
713-798-6985
Website
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Structural and Computational Biology of Biological Machines; Biological applications include viruses, ion channels, membranes, oligomeric proteins and cyotskeletal protein complexes. Dr. Chiu has been a leading investigator in the development of electron cryomicroscopy to solve structures of macromolecular assemblies at increasingly high resolutions. Computationally, his group has developed single particle reconstruction software, which has been widely adopted by other investigators. He directs an NIH supported center (http://ncmi.bcm.edu). Among many structures his group has done, Chiu is pursuing the structural studies of viruses including herpes simplex virus, bacteriophages andVenezuelan equine encephalitis virus. His approach includes single particle and tomographic electron cryomicroscopy.
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Chow , Dar-chone
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Assistant Professor
Chemistry
University of Houston
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Email
713-743-1798
Website
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One research goal in our laboratory is to understand the basis of conformational changes in the function of a protein.
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Clark, Jr. , John W.
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Professor
Elec & Comp Engineering
Rice University
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Email
713-348-3597
Website
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Biological Systems Modeling, Medical Electronics
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Clementi , Cecilia
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Associate Professor
Chemistry
Rice University
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Email
713-348-3485
Website
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Theory of protein Folding; computational molecular biology
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Cody, Dianna
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Professor
Imaging Physics
UT M. D. Anderson Cancer Center
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Email
713-792-5545
Website
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3D imaging methods; finite element modeling; prediction of mechanical bone characteristics; medical image processing; lesion volume determination and measurement precision
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Colvin, Vicki L.
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Professor/Executive Director, CBEN
Chemistry
Rice University
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Email
713-348-5741
Website
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Nanocrystals and photonic band gap materials
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Conneely, Orla M.
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Ph.D
Molecular and Cellular Biology
Baylor College of Medicine
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Email
713-798-6233
Website
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Coombes, Kevin
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Research Associate Professor
Biostatistics
UT M. D. Anderson Cancer Center
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Email
713-794-4154
Website
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Analysis of microarray data; Development of programming tools for bioinformatics; Multivariable calculus; Applications of differential equations in computing
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Cooney, Austin
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Assistant Professor
Cell Biology
Baylor College of Medicine
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Email
713-790-1275
Website
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Regulation of gene expression by orphan nuclear receptors
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Cooper, Cary
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Pharmacology
UT Medical Branch at Galveston
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Email
409-772-1902
Website
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Cox, Alan L
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Associate Professor
Computer Science
Rice University
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Email
713-348-5730
Website
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parallel processing, computer architecture, distributed systems, concurrent programming, and performance evaluation
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Cox, Dennis Dean
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Professor
Statistics
Rice University
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Email
713-348-6007
Website
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Computational Statistics, Nonparametric Function Estimation, Spatial Statistics, Time Series Analysis, Data Mining, Computational Statistics, Monte Carlo methods, Environmetrics, Bayesian Methods, Applied Statistics, Theoretical Statistics, Probability Theory
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Cox, Steven J
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Professor
Comp & Applied Mathematics
Rice University
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Email
713-348-5192
Website
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inference of material properties from electrical and optical recordings from single nerve cells
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Cruz, Miguel
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Assistant Professor
Medicine Thrombosis
Baylor College of Medicine
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Email
713-798-3470
Website
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define the molecular basis of platelet adhesion, particularly the mechanism by which VWF adheres to collagen coated surfaces, is then activated and binds to the platelet GpIb receptor. Our lab is also studying the structure and function of the platelet collagen receptor GPIa/IIa (integrin a2b1).
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Czernuszewicz, Roman
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Associate Professor
Chemistry
University of Houston
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Email
713-743-3235
Website
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Analytical-Bioinorganic Chemistry
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Davey, Robert
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Assoc Professor
Microbiology and Immunology
UT Medical Branch at Galveston
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Email
409-772-4915
Website
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Our research focuses on how membrane enveloped viruses enter cells. Understanding this event would aid the development of drugs to prevent the cell to cell spread of viruses such as HIV. Research mixes Virology and Structural Biology to dissect the trigger mechanism and the molecular motor that drive the fusion of the viral and cell membranes. We are working on Murine Leukemia Viruses but will soon look at other enveloped viruses that cause human disease; Use of nanoscale technologies to treat human genetic and infectious disease.
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Davies, Peter
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Ex VP Research
Administration
UT Health Science Center at Houston
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Email
713-500-3082
Website
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biology and pharmacology of the Retinoid X Receptor (RXR), of the factors controlling the expression of the enzyme tissue transglutaminase
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Davis, Ronald L.
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Professor/R. P. Doherty-Welch Chair in Science
Department of Molecular and Cellular Biology
Baylor College of Medicine
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Email
713-798-6641
Website
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We study genes that have known or suspected roles in learning and memory processes.
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Deem , Michael W.
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John W. Cox Professor
Bioengineering
Rice University
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Email
713-348-5852
Website
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Vaccine design; physical theories of pathogen evolution and the immune response; Newton's laws of biology.
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Delcour, Anne
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Professor
Biology and Biochemistry
University of Houston
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Email
713-743-2684
Website
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molecular mechanisms of ion channel function and modulation
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Dessauer, Carmen
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Associate Professor
Medical School
UT Health Science Center at Houston
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Email
713-500-6308
Website
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Structural, biochemical, and molecular biology techniques; Dynamics of cAMP production by signaling complexes at the plasma membrane
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Dickinson, Mary
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Assistant Professor
Molec.Physiology
Baylor College of Medicine
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Email
713-798-2104
Website
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My laboratory uses a multi-disciplinary approach to study the role of fluid-derived mechanical forces in vascular remodeling and heart morphogenesis in early vertebrate embryos. We have recently developed methods for time-lapse, confocal imaging of rapid blood flow and heart mechanics using vital fluorescent protein reporters. With these methods we are studying the response to changes in mechanical stress in mouse and zebrafish models, taking advantage of the wealth of mutant animals.
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Drezek, Rebekah A.
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Professor
Bioengineering
Rice University
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Email
713-348-3011
Website
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Nanotechnology; molecular imaging; biophotonics
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Embree , Mark Patrick
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Assistant Professor
Comp & Applied Mathematics
Rice University
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Email
713-348-6160
Website
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Krylov subspace methods for linear systems and eigenvalue problems; Nonnormal operators and spectral perturbation theory; Toeplitz matrices, random matrices.
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Ensor , Katherine
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Professor
Statistics
Rice University
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Email
713-348-4687
Website
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Time series including categorical time series, spatial statistics, spatial-temporal methods, estimation for stochastic process and environmental statistics
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Epstein, Henry
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Professor and Chair
ANATOMY & NEUROSCIENCES
UT Medical Branch at Galveston
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Email
(409) 772-1826
Website
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Fang, Bingliang
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Thoracic and Cardiovascular Surgery
UT M. D. Anderson Cancer Center
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Email
713-794-4039
Website
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Special interests in drug discovery and development, cancer biology and tumor targeting.
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Fitzgibbon , William E.
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Professor & Chair, Department of Mathematics
Mathematics
University of Houston
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Email
713-743-3455
Website
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My interests lie in the application of reaction-diffusion equations and other coupled distributed parameter systems to problems in mathematical biology especially in population biology, epidemiology and the environment.
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Fofanov, Yuriy
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Assistant Professor
Computer Sciences
University of Houston
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Email
713-743-8553
Website
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Causality in genetic networks; Microarray technology; Gene/Protein expression; Sequence analysis; Structural identification of nonlinear dependencies; Mathematical methods of discovering non-linear conformities in experimental data; Informativity and planning of experiments on discovering nonlinear regularity
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Fox, George E.
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Professor
Biology and Biochemistry
University of Houston
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Email
713-743-8363
Website
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Molecular Evolution, Bioinformatics, RNA structure and Evolution, Origin of Life, Environmental Monitoring, Molecular Biology, Array Hybridization; Protein folding, genomics, proteomics and systems biology
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Fox , Robert O.
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Professor
Biochemistry and Molecular Biology
UT Medical Branch at Galveston
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Email
409-772-2163
Website
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Our laboratory investigates the structural basis of macromolecular interactions using a variety of biophysical tools including X-ray crystallography and NMR spectroscopy. The general goal of our laboratory is to determine the manner in which amino acid sequence information promotes the formation of stable folded globular protein molecules and modulates the affinity and specificity of protein ligand interactions. We use molecular genetic tools to produce variant protein molecules for characterization by biophysical methods.
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Gabbiani, Fabrizio
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Associate Professor
Division of Neuroscience
Baylor College of Medicine
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Email
713-798-1849
Website
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Biophysics of information processing in the nervous system
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Gao, Xiaolian
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Professor
Chemistry
University of Houston
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Email
713-743-2805
Website
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Biophysical and organic chemistry; Research in the laboratory is at the interfaces of chemistry and biological sciences. Our work focuses on two areas: (1) Biological NMR of nucleic acids, proteins, and their complexes with ligand molecules. (2) Microarray BIOCHIP technologies in synthesis and applications.
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Gelovani, Juri
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Radiology and Neurology
UT M. D. Anderson Cancer Center
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Email
713-563-3343
Website
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Ghorbel , Fathi H.
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Associate Professor
Mechanical Engr & Materials Sci
Rice University
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Email
713-348-3738
Website
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Control Systems, Robotics,
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Gibbs , Richard
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Professor
Human Genome Sequencing Center
Baylor College of Medicine
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Email
713-798-6539
Website
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The Human Genome Project; molecular basis of human genetic diseases; molecular evolution.
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Gilbert, Hiram
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Associate Dean Graduate School Professor
Biochemistry
Baylor College of Medicine
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Email
713-798-5880
Website
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Protein Folding
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Gilbertson, Scott R.
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M. D. Anderson Professor
Chemistry
University of Houston
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Email
713-743-8821
Website
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Development of Chemistry for Small Molecule Library Synthesis; Total Synthesis and Medicinal Chemistry of Biologically Important Natural Products; Rhodium Catalyzed Synthesis of Medium Sized Rings; Peptide Based Catalysts.
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Glantz , Raymon M
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Professor
Biochemistry & Cell Biology
Rice University
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Email
713-348-4915
Website
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Neurophysiology, computational biology, sensory information processing, neural networks.
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Goldman, Ronald
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Professor
Computer Science
Rice University
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Email
713-348-5729
Website
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My current research interests lie in the mathematical representation, manipulation, and analysis of shape using computers. I am particularly interested in algorithms for polynomial and piecewise polynomial curves and surfaces, and I have investigated both parametrically and implicitly represented geometry. My current work includes research in computer aided geometric design, solid modeling, computer graphics, and splines.
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Gorenstein, David G.
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Professor and Deputy Director
The Brown Foundation Institute of Molecular Medicine
UT Health Science Center at Houston
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Email
713-500-2408
Website
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Proteomics and nanomedicine for both diagnostics and therapeutics in both infectious diseases and cancer; structural biology, drug design, nucleic acid and protein chemistry
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Gorry , Tony
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Professor of Computer Science
Jones Graduate School of Management
Rice University
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Email
713-348-6054
Website
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Information technology to support information acquisition, sharing and management in collaborative work.
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Grande-Allen, K. Jane
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Associate Professor
Bioengineering
Rice University
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Email
713-348-3704
Website
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Work in my laboratory uses the engineering analysis of tissue composition and behavior to investigate tissue and cellular responses to disease, using the cardiac valves as a paradigm for other soft tissues. My research interests include: integrative biomechanics, biochemistry, pathology, & therapies of heart valve disease; extracellular matrix; proteoglycans, organ cultured & tissue engineered surrogates for studies of soft tissue biology & disease.
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Graur, Dan
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John and Rebecca Moores Professor
Department of Biology & Biochemistry
University of Houston
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Email
713-743-7236
Website
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Molecular Evolution, Phylogenetic Methodology, Patterns of Protein Evolution, Patterns of Pseudogene Evolution, Detection of Selection, Phylogeny and Evolution of Mammalian Orders and Suborders, Societal Aspects of Genetics, Genetic Engineering and Eugenics
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Greenberg, Stephen B.
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Professor
Department of Medicine
Baylor College of Medicine
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Email
713-798-4775
Website
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I have been involved in the impact of respiratory viral infections in asthmatic and COPD patients. In addition I have been defining the role of non-typeable Hemophilus influenzae (NTHi) in COPD patients as a major cause of exacerbations. These studies have led to a rethinking of the relative importance of viruses such as rhinoviruses and parainfluenzaviruses in causing exacerbations
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Guerra, Rudy
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Associate Professor
Statistics
Rice University
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Email
713-348-5453
Website
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I am generally interested in biological problems with an emphasis in biomedical research
|
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Guerrero, Thomas
|
Assistant Professor
Radiation Oncology
UT M. D. Anderson Cancer Center
|
Email
713-563-2300
Website
|
|
My research focus borders medical imaging and radiation oncology. On the imaging side, my focus is on deformable image registration algorithms and applications. On the radiation oncology side, the goal of this research is to develop imaging procedures that may be utilized in the radiotherapy treatment planning and to follow radiation injury to the lung after treatment. I plan to develop animal models of regional pulmonary biomechanical compliance in rodents and cardiac wall motion in dogs using CT and optical flow. With these I will investigate the temporal course and dose response to radiation and radio-protectors.
|
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Gustin, Mike
|
Associate Professor
Biochemistry and Cell Biology
Rice University
|
Email
713-348-5158
Website
|
|
Molecular genetics and biochemistry of signal transduction.
|
|
Hafner, Jason
|
Associate Professor
Physics and Astronomy
Rice University
|
Email
713-348-3205
Website
|
|
Nanometer-scale tools to study biological systems
|
|
Halas, Naomi
|
Stanley C. Moore Professor
Elec & Comp Engineering
Rice University
|
Email
713-348-5611
Website
|
|
Development of nanoscale tools and devices for intracellular sensing, spectroscopy and detection of biomolecules, and applications in cancer diagonostics and therapeutics
|
|
Hartgerink, Jeffery Dale
|
Associate Professor
Chemistry
Rice University
|
Email
713-348-4142
Website
|
|
Supramolecular chemistry
|
|
Hauge, Robert H.
|
Chemistry
Rice University
|
Email
(713) 348-6384
Website
|
|
Physical, inorganic and materials chemistry
|
|
Hazle, John D.
|
Professor and Dept. Chair
Imaging Physics
UT M. D. Anderson Cancer Center
|
Email
713-792-0612
Website
|
|
Magnetic resonance imaging, interventional ultrasonography, induced hyperthermia
|
|
He, Xiangwei
|
Assistant Professor
Mol. & Human Gen
Baylor College of Medicine
|
Email
713-798-2093
Website
|
|
Chromosome Segregation: Interaction Between Spindle and Kinetochores. Research in my laboratory aims at a specific aspect of chromosome segregation, namely, how the proper interaction between spindle microtubules and kinetochores is established and maintained. Our model organism is the fission yeast, Schizosacchromyces pombe. Our short term goal is to dissect the protein composition of the kinetochore in fission yeast to provide the structural basis for functional study. Using genetic approaches, we isolated mutants that specifically disrupt kinetochore functions. We also take the biochemical approach to purify and analyze kinetochore proteins that are of minute amount in the cell.
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Heinkenschloss , Matthias
|
Associate Professor
Comp & Applied Mathematics
Rice University
|
Email
713-348-5176
Website
|
|
Optimization, Optimal Control and Parameter Identification, Partial Differential Equations
|
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Herzog, Norbert K.
|
Professor and Assistant Dean, GSBS; Member Faculty, WHO Collaborating Center for Tropical Diseases
Department of Pathology
UT Medical Branch at Galveston
|
Email
409-772-2618 /
Website
|
|
My laboratory is engaged in research into the processes of cellular signal transduction and their role in disease pathogenesis. I study the role of cellular transcription factors in normal cellular signal transduction in an effort to understand how alterations in these systems lead to or contribute to diseases such as cancer and infectious diseases. Lassa Fever, and many other hemorrhagic fever viruses as well as West Nile virus are on the select list of bioterrorist threat agents.
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Hess, Kenneth
|
Associate Professor
Biostatistics
UT M. D. Anderson Cancer Center
|
Email
713-794-4157
Website
|
|
Biostatistics, clinical trials, pathologic neovascularization, genomics
|
|
Hilser, Vincent
|
Professor
Biochemistry and Molecular Biology
UT Medical Branch at Galveston
|
Email
409-747-6813
Website
|
|
Research in our lab is focused on the experimental characterization of conformational fluctuations, the development and refinement of a general ensemble-based model for fluctuations, and the projection of this thermodynamic model into genomic analysis. Our goals are to unify the description of protein behaviors in such a way as to understand their relationships at the phenomenological level, to codify these relationships in a simple structure-based model, and to apply our model to a number of experimental systems that can be used to test and refine our approach.
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|
Holland, Nat
|
Assistant Professor
Ecology and Evolutionary Biology
Rice University
|
Email
713-348-3987
Website
|
|
Hu, Ming
|
Professor of Pharmaceutics
Pharmacological and Pharmaceutical Sciences
University of Houston
|
Email
713-795-8320
College of Pharmacy
|
|
Interests targeted in the development of pills for prevention of colon and hormone related cancers. Ongoing project involves the improvement of bioavailability of chemopreventive agents. Other areas are focusing on purifying anticancer ingredients of herbal materials and decreasing the bioavailability of dietary carcinogens.
|
|
Huang, Huey
|
Sam & Helen Worden Professor
Physics and Astronomy
Rice University
|
Email
713-348-4899
Website
|
|
membrane-membrane interactions (fusions) and protein-membrane interactions
|
|
Hussain, Tahir
|
Assistant Professor
Department of Pharmacological
University of Houston
|
Email
(713) 743-1274
Website
|
|
To understand the role of renal angiotensin and dopamine receptors and associated cellular signaling pathways in obesity/diabetes related hypertension
|
|
Igoshin, Oleg
|
Assistant Professor
Bioengineering
Rice University
|
Email
713-348-5502
Website
|
|
Evolutionary design principles of master level gene expression regulation in bacteria; Organization and evolution of intercellular signaling networks in bacterial communication; Spatial organization, dynamics and metabolism in bacterial communities
|
|
Iwahara, Junji
|
Assistant Professor
Department of Biochemistry and Molecular Biology
UT Medical Branch at Galveston
|
Email
409-747-1403
Website
|
|
target search process whereby gene-regulatory proteins are able to efficiently and rapidly locate their specific DNA target sequence in a sea of non-specific DNA
|
|
Iyengar, M Sriram
|
Assistant Professor
School of Health Information Sciences
UT Health Science Center at Houston
|
Email
713-500-3976
|
|
Dr. Sriram has focused his research in bio-medical informatics Research & Development including mathematical/statistical modeling, algorithms, and software development across diverse areas such as biochemistry, immunohematology, endocrinology, oncology, orthopedics, neural imaging, and clinical trials.
|
|
Jacobson, Raymond
|
Assistant Professor
Biochemistry & Molecular Biology
UT M. D. Anderson Cancer Center
|
Email
713-834-
Website
|
|
Biochemical and 3-Dimensional Structure Analysis of Basal Transcription Proteins/Complexes
|
|
Jayaraman, Vasanthi
|
Associate Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
|
Email
713-500-6236
Website
|
|
Structure and function; membrane bound proteins; ion channels
|
|
Jing, Naijie
|
Assistant Professor
Medicine Infectious Disease
Baylor College of Medicine
|
Email
713-798-8918
Website
|
|
Johnson, Don H
|
J.S. Abercrombie Professor
Elec & Comp Engineering
Rice University
|
Email
713-348-4956
Website
|
|
Statistical signal processing; theoretical neuroscience
|
|
Johnsson, Lennart
|
Cullen Distinguished Professor
Computer Sciences
University of Houston
|
Email
713-743-3371
Website
|
|
Computational and data grids
|
|
Johnston, Daniel
|
Professor
Division Of Neuroscience
Baylor College of Medicine
|
Email
713-798-5984
Website
|
|
Cellular neurophysiology and membrane biophysics; mechanisms of synaptic plasticity in hippocampus.
|
|
Kakadiaris, Ioannis
|
Professor
Computer Science
University of Houston
|
Email
713-743-1255
Website
|
|
Biomedical image analysis, modeling, and simulation; Computational biomedicine; Computer vision; Pattern recognition
|
|
Kaplan, Samuel
|
Professor and Chairman
Microbiology And Molecular Gen
UT Health Science Center at Houston
|
Email
(713) 500-5502
Website
|
|
Role of oxygen and light in the regulation of gene expression and the nature of genome complexity in microorganisms. How the flux of cellular reductant through the various redox pools and terminal oxidases serves to regulate gene expression; the roles of assembly factors and redox intermediates in regulating the assembly of membrane complexes; the use of DNA chip technology to understand how redox-mediated signals serve to regulate global gene expression.
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|
Kavraki , Lydia
|
Noah Harding Professor of Computer Science & Professor of Bioengineering
Computer Science and Bioengineering
Rice University
|
Email
713-348-5737
Website
|
|
Kavraki's group develops computational tools on high-performance systems to model protein structure and function, understand biomolecular interactions and help analyze, in the long run, the molecular machinery of the cell. This is done by integrating sequence information with three-dimensional structural information to capture, represent and exploit relevant molecular motion. Of particular interest are the identification of three-dimensional functional motifs in protein databases, docking of flexible molecules to flexible receptors, computer-assisted drug discovery, and the understanding and compact representation of structural changes in large biomolecular machines.
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|
Keitel, Wendy A.
|
Associate Professor
Department of Molecular Virology and Microbiology
Baylor College of Medicine
|
Email
713-798-5250
Website
|
|
We are interested in the development and evaluation of a number of vaccines, with a particular emphasis on prevention of respiratory infections. Our group is involved in both the preclinical and clinical stages of vaccine development, including phase I to phase III clinical trials. Recent research activities have focused on the development of live attenuated and improved inactivated influenza virus vaccines, acellular pertussis vaccines, and pneumococcal vaccines. Major goals for improved vaccines include enhancement of mucosal and cell-mediated immune responses.
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|
Kiang, Ching-Hwa
|
Assistant Professor
Physics and Astronomy
Rice University
|
Email
713-348-4130
Website
|
|
Molecular biophysics; soft condensed matter physics
|
|
Kimmel, Marek
|
Professor
Statistics
Rice University
|
Email
713-348-5255
Website
|
|
Informatics and statistical modeling of genome dynamics
|
|
Kirken, Robert
|
Assistant Professor
Integrative Biology & Pharm
UT Health Science Center at Houston
|
Email
+1 (713) 500-63
|
|
Klimpel, Gary R.
|
Professor
Department of Microbiology and Immunology
UT Medical Branch at Galveston
|
Email
409-772-4917
Website
|
|
Two areas of immunobiology are investigated in this laboratory. One area is the study of how the human innate immune response is affected by Francisella tularensis, a select agent, Category A on the NIAID list of priority pathogens. This work involves investigating human monocytes, macrophages, NK cells, and dendritic cells. We are interested in comparing avirulent versus virulent bacteria. A second project involves investigating the immunobiology of leptospirosis, a very problematic disease of underdeveloped countries, caused by a spirochete of the genus Leptospira. In this study, we are investigating not only the human innate immune response but also T cell memory responses.
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|
Koehler, Theresa M.
|
Professor
Department of Microbiology and Molecular Genetics
UT Health Science Center at Houston
|
Email
713-500-5450
Website
|
|
Our lab studies the genetics, physiology and virulence in the gene expression of Bacillus anthracis. Work is focused on the pathogenesis of anthrax, host-parasite relationship and signal transduction. Bacillus anthracisis distinguished by its ability to cause anthrax in mammals. Depending upon the route of entry, infection with spores can result in cutaneous disease, which is readily treatable with antibiotics, or systemic disease, which is often fatal. The continuing worldwide incidence of anthrax in animal populations, risk of human infection associated with animal outbreaks, and potential for use of B. anthracis as a biological weapon, warrant continued investigation of this organism and its virulence mechanisms
|
|
Koelbel , Charles H
|
Research Scientist
Computer Science
Rice University
|
Email
713-348-5868
Website
|
|
Chuck Koelbel's research interests center on mapping algorithms and programs onto distributed memory multiprocessors.
|
|
Kolomeisky, Anatoly B.
|
Associate Professor
Chemistry
Rice University
|
Email
713-348-5672
Website
|
|
Theoretical physical chemistry and biophysics
|
|
Kulmacz, Richard
|
Professor
Medical School
UT Health Science Center at Houston
|
Email
713-500-6772
Website
|
|
Eicosanoid Biosynthesis
|
|
Lau, Ching C.
|
Associate Professor
Pediatrics
Baylor College of Medicine
|
Email
713-798-4543
Website
|
|
molecular biology of pediatric brain and bone tumors and the clinical applications of genomic technologies.
|
|
Leal, Suzanne M.
|
Professor
Dept. of Molecular & Human Genetics
Baylor College of Medicine
|
Email
713-798-4011
Website
|
|
My interest in statistical genetics/genetic epidemiology lies in the mapping of complex and Mendelian traits and understanding the interactions between genes and between genes and the environment. In addition to applied work of localizing disease loci through statistical genetic methods, I am interested in methodological research.
|
|
Ledlie , Betty
|
Coord Admin Sr
Huffington Center On Aging
Baylor College of Medicine
|
Email
713-798-6661
|
|
Lee, Angel Wai-mun
|
Associate Professor
School of Health Information Sciences
UT Health Science Center at Houston
|
Email
713-500-3852
Website
|
|
Understanding Signal Transduction in hematopoiesis and neurogenesis
|
|
Lee, James C.
|
Professor
Biochemistry and Molecular Biology
UT Medical Branch at Galveston
|
Email
409-772-2281
Website
|
|
My laboratory is interested in elucidating the molecular mechanisms of regulation, in particular, the ground rules employed in recognizing specific targets and transmitting of signals among these macromolecular components.
|
|
Legge, Glen
|
Assistant Professor
Biology and Biochemistry
University of Houston
|
Email
713-743-8380
Website
|
|
structural biology to link the fields of biology and chemistry by an understanding of the molecular mechanisms of biological processes
|
|
Lemon, Stanley
|
Dean
Department of Medicine
UT Medical Branch at Galveston
|
Email
(409) 772-4793
Website
|
|
The research in my lab focuses on hepatitis C and hepatitis A viruses: two plus-strand RNA viruses that cause significant disease in human populations. We are particularly interested in building better model systems for hepatitis C, and in characterizing the mechanisms by which these virus RNAs initiate cap-independent translation of their polyprotein.
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|
Li, Renhao
|
Assistant Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
|
Email
713-500-7233
Website
|
|
Molecular regulation and structural basis of transmembrane signaling
|
|
Lichtarge, Olivier
|
Professor
Molecular & Human Genetics
Baylor College of Medicine
|
Email
713-798-5646
Website
|
|
Protein functional surfaces; assembly of active complexes
|
|
Liebschner, Michael
|
Associate Professor
Neurosurgery
Baylor College of Medicine
|
Email
713-798-4696
|
|
Research Interests: Spine/Bone Biomechanics, Computational Biomechanics, Tissue Engineering, Tissue Fracture Mechanics
|
|
Lokhandwala, Mustafa F.
|
Executive Vice Dean for Research and Professor of Pharmacology
Department of Pharmacological and Pharmaceutical Studies
University of Houston
|
Email
(713) 743-1259
Website
|
|
Loose, David
|
Associate Professor & Dir
Integrative Biology & Pharm
UT Health Science Center at Houston
|
Email
(713) 500-7440
Website
|
|
Lopez-Berestein, Gabriel
|
Bioimmunotherapy
UT M. D. Anderson Cancer Center
|
Email
713-792-8143
Website
|
|
Ludtke, Steve
|
Associate Professor
Biochemistry
Baylor College of Medicine
|
Email
713-798-6989
Website
|
|
My work involves the 3D reconstruction of molecules and macromolecules using a technique called single particle reconstruction. My most significant contribution to the field is the development of the EMAN software package (see below), which performs semi-automated processing of individual molecule images to produce accurate 3D reconstructions.
|
|
Luxon, Bruce
|
Director, Professor
UTMB Bioinformatics Program, Dept. of Biochemistry and Molecular Biology
UT Medical Branch at Galveston
|
Email
409-747-6802
Website
|
|
Metabolomics studies related to diabetes, occupational exposure, cancer, addiction, and infectious disease. We specialize in integrating these data with parallel experiments including genomics, proteomics, kinomics, lipidomics, and LC/MS metabolomics.
|
|
Ma , Jianpeng
|
Associate Professor
Bioengineering
Rice University
|
Email
713-348-5713
Website
|
|
Simulation of supermolecular complexes; computer-aided drug-design. Our group is using combined experimental and computational methods to study the fusion mechanisms of influenza virus, especially the hemagglutinin-mediated cell membrane fusion. Of particular interest is to derive structural information for intermediates along the pH-triggered conformational transition, which is an extremely difficult problem. We will employ a suite of biophysical techniques including various imagining methods and computer simulation techniques.
|
|
MacKenzie , Kevin R
|
Assistant Professor
Biochemistry & Cell Biology
Rice University
|
Email
713-348-2228
Website
|
|
Structure and stability of membrane proteins
|
|
Mancini, Michael A.
|
Associate Professor
Cell Biology
Baylor College of Medicine
|
Email
713-798-8952
Website
|
|
Functional relationship(s) between dynamic nuclear organization and transcription
|
|
Marshak, David
|
Professor
Neurobiology and Anatomy
UT Health Science Center at Houston
|
Email
713-500-5617
Website
|
|
Neural circuits in the primate retina; Retinal ganglion cells and perception of motion; Dopamine and light adaptation; Morphology and synaptic connections of local circuit neurons
|
|
Matthews, Kathleen S
|
Stewart Memorial Professor, Biochemistry/Cell Bio
Wiess School of Natural Sciences
Rice University
|
Email
713-348-4871
Website
|
|
Structure and function of genetic regulatory proteins
|
|
McMurray, John
|
Associate Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
|
Email
713-745-3763
Website
|
|
Bio-organic chemistry, peptide and peptidomimetic chemistry, structure-guided drug design, protein-protein interaction, enzyme inhibitor design. Our work concerns the design of inhibitors of important protein-protein interactions with the overall goal of developing chemotherapeutic agents as well as reagents to probe signal transduction mechanisms. Our current targets are the STAT (signal transduction and activator of transcription) proteins. Our strategy is to find high affinity peptides to inhibit target protein-protein interactions, determine which parts of the peptide contributes to binding energy, determine the bound conformation, then combine this information to develop small molecule inhibitors that mimic the action of the peptide. Another strategy is screening a small molecule library to find leads.
|
|
McNew, James
|
Assistant Professor
Biochemistry & Cell Biology
Rice University
|
Email
713-348-3133
Website
|
|
Molecular mechanism of biological membrane fusion. We use biochemistry, cell biology and molecular genetic techniques to study membrane fusion in two major model systems: vesicular transport in the budding yeast S. cerevisiae and neurosecretion in the fruitfly D. melanogaster. A primary focus of the lab is the functional reconstitution of exocytosis in the yeast. Another focus of the lab is the regulation of neuroscretion. We use our in vitro reconstituted fusion system containing SNARE proteins from Drosophila to examine neuronal specific regulatory factors.
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|
Mikos, Antonios G.
|
J. W. Cox Professor, Director of J. W. Cox Lab for Biomedical Engineering
Bioengineering
Rice University
|
Email
(713)348-5355
Website
|
|
Biomaterials; drug delivery; gene therapy; tissue engineering. The synthesis, processing, and evaluation of new biomaterials for tissue engineering, scaffolds for three-dimensional cell culture, conduits for guided tissue regeneration, substrates for targeted cell adhesion, carriers for controlled drug delivery, and non-viral vectors for gene therapy. We are also developing new CAD/CAM and polymer chemistry fabrication technologies for the production of synthetic biomimetic materials that exhibit the mechanical responsiveness and biochemical processing capabilities of living cells and tissues.
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|
Mills, Gordon
|
Professor and Chair
Department of Molecular Therapeutics
UT M. D. Anderson Cancer Center
|
Email
713-563-4200
Website
|
|
Our research program aims to identify the mechanisms by which normal cells (lymphocytes) and tumor cells (ovarian and breast cancer) perceive and respond to their environment. The mission of the laboratory is to understand the mechanisms by which signal transduction is linked to proliferation, invasion, and programmed cell death in T lymphocytes and in breast and ovarian cancer.We recently identified a unique phospholipid growth factor, OCAF, in the ascites of ovarian cancer patients. We will explore the role of OCAF in early diagnosis, establishment of prognosis, monitoring of therapy, and therapy of breast and ovarian cancer patients.
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|
Milosavljevic, Aleksandar
|
Associate Professor
Human Genome Sequencing Center
Baylor College of Medicine
|
Email
713-798-8719
Website
|
|
Bioinformatics and Comparative Genomics. Pooled Genomic Indexing (PGI). In a first genome-scale application of PGI, our lab is mapping a whole-genome BAC library of rhesus macaque onto human genomic sequence. Clone-Array Pooled Shotgun Sequencing (CAPSS). Comparative Sequence Assembly. We are further refining and applying methods and software for comparative assembly on the scale of mammalian genomes. Genome-scale Sequence Comparison Methods. One of our goals is to enable comparison of genomes at arbitrary levels of sequence assembly and to enable comparative assembly of shotgun fragments. Genboree (http://www.genboree.org). Genboree is an ¿electronic whiteboard¿ for sharing and development of sequence assemblies and annotations.
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|
Mittleman, Daniel M.
|
Associate Professor
Elec & Comp Engineering
Rice University
|
Email
713-348-5452
Website
|
|
THz spectroscopy and imaging; Photonic crystals; Our current research involves the generation and detection of sub-picosecond pulses of far-infrared radiation.
|
|
Montague, Jr., P Read
|
Professor
Division Of Neuroscience
Baylor College of Medicine
|
Email
713-798-3134
Website
|
|
Computational neuroscience - the connection between the physical mechanisms present in real neural tissue and the computational functions that these mechanisms embody. Work in the Montague group also extends into several experimental areas including synaptic physiology, human neuroimaging, and human behavior.
|
|
Moore, David
|
Professor
Cell Biology
Baylor College of Medicine
|
Email
713-798-3313
Website
|
|
Functions of Nuclear Hormone Receptors. Current efforts focus on three that have emerged as key regulators of metabolic pathways in the liver: CAR, FXR and SHP. We use pharmacologic and mouse knockout approaches to define the metabolic regulatory functions of the nuclear hormone receptors
|
|
Morrisett , Joel
|
Professor
Medicine Athero & Lipo
Baylor College of Medicine
|
Email
713-798-4164
Website
|
|
Imaging, Genomics, and Proteomics of Human Atherosclerosis; elucidating the mechanism(s) whereby Lp[a] exerts its atherogenic effects; The apo[a] protein; Peptide segmenets found in the proline-rich motif of cytokine receptors are under study using the techniques of molecular modeling, circular dichroism, and nuclear magnetic resonance spetroscopy.
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|
Mueller, Peter
|
Professor
Biostatistics & Applied Math
UT M. D. Anderson Cancer Center
|
Email
713-563-4296
Website
|
|
Numerical integration in Bayesian Statistics, Markov Chain Monte Carlo methods, Simulation based optimal design, Mixture of Dirichlet process models, Neural network models, Longitudinal data models, Pharmacokinetic/pharmacodynamic models, Case-control studies, Hierarchical models, Dynamic models, Nonparametric Bayes.
|
|
Murad, Ferid
|
Scientific Director ; RegProf, Chr & Dunn DistCh IBP
IMM ; Integrative Biology & Pharm
UT Health Science Center at Houston
|
Email
(713) 500-7509
Website
|
|
My research focuses on the formation, metabolism and function of nitric oxide and cyclic GMP as they participate in various cellular signaling processes. Some of our current research is focusing on the formation of peroxynitrite from nitric oxide and the nitration of various cellular proteins.
|
|
Murray, Barbara
|
Professor
Internal Medicine, Infectious
UT Health Science Center at Houston
|
Email
(713) 500-6767
Website
|
|
The genetic and biochemical mechanisms of resistance to antibiotics and bacterial pathogenicity, particularly relating to enterococci, and molecular epidemiologic typing methods; Defining the enterococcal antigens that elicit antibody responses in infected patients, generation of isogenic mutants for studies of virulence, testing the potential protective effect of antiserum, identification of gene(s) encoding adherence to extracellular matrix proteins and characterization of a polysaccharide biosynthesis gene cluster of E. faecalis
|
|
Nakhleh, Luay
|
Assistant Professor
Computer Science
Rice University
|
Email
713-348-3959
Website
|
|
Bioinformatics and computational biology. In this area I work on reticulate evolution, multi-locus genotype-phenotype inference, and biological signaling networks. Historical linguistics. In this area, I work on developing computational methods for reconstructing the evolution of natural languages and detecting borrowing among them.
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|
Navarro, Javier
|
Professor
Neuroscience and Cell Biology
UT Medical Branch at Galveston
|
Email
409-772-5480
Website
|
|
The molecular mechanism of G protein-coupled receptors; Applying X-ray crystallography to elucidate the atomic structure of seven-helix transmembrane receptors; Genetic and biophysical approaches to determine the role of specific domains.
|
|
Nelson , David
|
Professor
Mol. & Human Gen. Nelson Lab
Baylor College of Medicine
|
Email
713-798-4787
Website
|
|
The identification of unstable trinucleotide repeats involved in high frequency mutations leading to genetic disorders, including myotonic dystrophy and Huntington's disease; The FMR1 and FMR2 genes; Genetic epidemiological studies to define gene variants with altered risks for tumor formation.
|
|
Nikonowicz, Edward
|
Associate Professor
Biochemistry & Cell Biology
Rice University
|
Email
713-348-4912
Website
|
|
RNA-Protein biochemistry, structure-function relationships in nucleic acid systems; In addition to NMR spectroscopy, we use biochemical, computational, and optical methods to investigate the kinetic, motional, and structural properties of the component molecules; The interaction of primary ribosomal proteins with their RNA targets; Post-transcriptional modification of tRNA.
|
|
O'Malley, Bert W.
|
Chairman/Professor
Academic Department
Baylor College of Medicine
|
Email
713-798-6205
Department
|
|
Regulation of eucaryotic gene expression; cell- and gene-specific transcriptional regulators.
|
|
O'Malley, Marcia
|
Assistant Professor
Mechanical Engr & Materials Sci
Rice University
|
Email
713-348-3545
Website
|
|
Modeling, design, and control of haptic interfaces; Modeling, design, and control of telemanipulation and human augmentation systems; Study of human-robot interactions.
|
|
Oberhauser , Andres
|
Associate Professor
Neuroscience and Cell Biology
UT Medical Branch at Galveston
|
Email
409-772-1309
Website
|
|
Protein folding and protein mechanics; The mechanism by which proteins respond to mechanical forces. Currently we are studying the mechanical properties of the cell matrix protein perlecan (an abundant component of the basal lamina), polycystin-1 (a cell membrane receptor) and projectin (a protein found in insect flight muscles).
|
|
Ogmen, Haluk
|
Professor
Electrical & Computer Engineering
University of Houston
|
Email
713-743-4428
Website
|
|
Neuro-engineering, vision, visual psychophysics, sensory-motor control, computational neuroscience.
|
|
Olson, John Steve
|
Dorothy/Ralph Looney Professor
Biochemistry & Cell Biology
Rice University
|
Email
713-348-4762
Website
|
|
Application of rapid reaction techniques to biophysical and biochemical problems; protein engineering by recombinant DNA technology; structural (X-ray, IR, and NMR) and functional studies of ligand binding to hemoglobins, myoglobins, and model heme compounds; design of heme protein-based blood substitutes; red blood cell physiology; biosynthesis of heme and hemoglobin; gas transport and exchange in capillaries.
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Osborne, C. Kent
|
Professor
Breast Cancer
Baylor College of Medicine
|
Email
713-798-1641
Home Page
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The molecular mechanisms for hormonal resistance in breast cancer focusing on crosstalks with growth factor signaling pathways, phosphorylation of estrogen receptor, and interaction with receptor coregulators.
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Palmer , Graham A
|
Professor Emeritus
Biochemistry & Cell Biology
Rice University
|
Email
713-348-4860
Website
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Mechanisms of oxidase enzymes
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Palzkill, Timothy
|
Chair and Professor
Pharmacology
Baylor College of Medicine
|
Email
713-798-5609
Website
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Molecular Basis of Antibiotic Resistance, Functional Genomics of Bacterial Pathogens
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Parry, Ronald J.
|
Professor
Chemistry
Rice University
|
Email
713-348-2446
Website
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Biosynthesis of natural products and the mechanisms of enzymatic reactions; Investigations of the biosynthesis of the phytotoxin coronatine, the antibiotic aristeromycin, and the antitumor agents sparsomycin and valanimycin.
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Pasquali, Matteo
|
Associate Professor
Chemical & Biomolecular Engineering
Rice University
|
Email
713-348-5830
Website
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The interaction of flow and liquid micro- and nano-structure; Microstructured liquids; Computational modeling of processing flows; Free surface flows; Visualization of flowing single DNA molecules; Rheology and phase behavior of Single-Walled Carbon Nanotubes; Rheology and microstructure of Polymeric Nanoparticles (particoils); Rheology and microstructure of Emulsions; Single-molecule behavior of semiflexible macromolecules.
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Pasqualini, Renata
|
Professor
Genitourinary Med Onc - Rsch
UT M. D. Anderson Cancer Center
|
Email
713-792-3872
Website
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Proteomics-- the systematic analysis of the proteins in biological samples that aims to document the overall distribution of proteins in cells, identify and characterize individual proteins of interest, and ultimately to elucidate their relationships and functional roles. Vascular proteomics-- the molecular phenotyping of cells forming blood vessels at the protein-protein interaction level. Identification, validation, and prioritization of molecular targets in human blood vessels. Identification of endothelial receptors expressed differentially in normal and pathological conditions and the isolation of peptides or antibody ligands.
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Pavlidis, Ioannis
|
Associate Professor
Computer Science
University of Houston
|
Email
713-743-0101
Website
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Computational Medicine: Bioheat Modeling, Vital Signs Computation. Computer Vision: Face Detection, Object Detection, Object Recognition, Object Tracking, Deformable Models, Automatic Target Recognition. Pattern Recognition: Classification, Handdrawn Sketch Recognition, Handwriting Recognition. Biometrics: Face Recognition, Facial Thermal Screening, Disguise Detection, Signature Identification. Robotics: Visual Servoing.
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Pedersen, Steen
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Associate Professor
Molec. Physiology Pederson
Baylor College of Medicine
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Email
713-798-3888
Website
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Allosteric mechanisms of ion channel function. Current research efforts in the lab comprise three general areas: structure-activity of ligand binding, kinetic analysis of conformational transitions, and determination of structural changes upon binding and conformational changes.
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Penczek, Pawel
|
Associate Professor
Biochemistry and Molecular Biology
UT Health Science Center at Houston
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Email
713-500-5416
Website
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We are interested in the determination of three-dimensional structures of large macromolecular complexes with low or non-existing symmetry in single-particle form using stain and cryo-electron microscopy (cryo-EM) and computer image processing techniques.
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Peters, Clarence (C.J.)
|
Professor; Director for Biodefense, Center for Biodefense and Emerging Infectious Diseases
Department of Pathology
UT Medical Branch at Galveston
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Email
409-772-0090
Website
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The pathogenesis and epidemiology of the viral hemorrhagic fevers and other emerging viral infections; Virology, immunology and structural biology applied to this field; Bunyaviridae (phleboviruses such as Rift Valley fever), Arenaviridae (Lassa fever, South American hemorrhagic fevers) and SARS CoV. He works closely with members of the trining center who are specialists in imaging to choose and execute experiments that are of biological significance and to prepare viruses for examination.
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Pettitt, B. Monte
|
Cullen Distinguished Professor
Chemistry
University of Houston
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Email
713-743-3263
Website
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Chemical physics; Physical chemistry; Biochemistry; Computer Science; Development of methods for calculating internal conformational structure and interpreting conformational equilibria of biomolecular solutes in aqueous environments; Structural and thermodynamic description of neat polar molecular fluids, including water, ions, polar biomolecular solutes and other condensed phase systems via integral equation and density functional methods; Development of theoretical techniques for the description of the thermodynamics and structure of ionic and anisotropic fluids; Development of methods to compare and search genomes
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Plunkett, William
|
Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
|
Email
713-792-3335
Website
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Cell cycle regulation, DNA repair, DNA synthesis, clinical pharmacology; Developing a molecular and biochemical understanding of how nucleoside analogues kill cells and how cells become resistant to these agents and to apply this knowledge to the design of clinical trials of combination therapies that will optimize therapeutic activity
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Poplack, David
|
Professor
Pediatrics-Hema & Oncology
Baylor College of Medicine
|
Email
832-822-4556
Baylor Home Page
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Prasad, B.V.
|
Professor
Biochemistry
Baylor College of Medicine
|
Email
713-798-5686
Website
|
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Structure-function relationships in medically important viruses. Three-dimensional structural analyses on viruses that are causative agents of endemic severe diarrhea in humans. These viruses include rotavirus, calicivirus, and Norwalk virus.
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Priebe, Waldemar
|
Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
|
Email
713-792-3777
Website
|
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Drug Design, Kinase Inhibitors, DNA Binding Agents, Drug Resistance, Hypoxia
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Putkey, John
|
Professor
Medical School
UT Health Science Center at Houston
|
Email
713-500-6061
Website
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My laboratory applies a synergistic blend of molecular and structural biology to study the molecular anatomy of calcium binding proteins; The mechanisms of regulation of calmodulin activity by post-translational modification and modulation of calmodulin binding to target proteins; Exploring the molecular mechanism of regulation of cardiac muscle contraction by calcium binding to cardiac troponin C, and how cardiotonic drugs lead to an increased efficiency of cardiac muscle contraction; Using NMR to reveal the strucutral basis behind why mutations in the extracelluar matix protein COMP lead to skeletal dysplasias and dwarfing syndromes.
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Qin, Jun
|
Associate Professor
Biochemistry
Baylor College of Medicine
|
Email
713-798-1507
Website
|
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Network analysis proteomics--dissecting signaling networks in which disease proteins function; the human DNA damage signaling network
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Queller, David C.
|
Professor
Ecology & Evolutionary Biology
Rice University
|
Email
713-348-5220
Website
|
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Evolutionary Biology: I work on both theoretical and empirical aspects of the evolution of social interactions, including both sexual selection and kin selection. Recent theoretical studies have focused on generalizing inclusive fitness theory, the role of relatedness in viscous populations, and the importance of demographic advantages in the evolution of sociality in insects.
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Quiocho, Florante
|
Professor
Hhmi Biochemistry
Baylor College of Medicine
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Email
713-798-6565
Website
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Structural Biophysics and Biology; X-Ray Crystallography of Proteins; Molecular Recognition and Protein-Ligand Interactions. Our research interest is centered on the study of the tertiary structure and function of proteins and enzymes at atomic resolution.
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Rajarathnam, Krishna
|
Assistant Professor
Neuroscience and Cell Biology
UT Medical Branch at Galveston
|
Email
409-772-2238
Website
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Exploiting the structural elements of chemokines and their receptors towards rational design of therapeutics. We are interested in understanding the molecular basis of ligand-receptor interaction.
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Raphael, Robert
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Associate Professor
Bioengineering
Rice University
|
Email
713-348-3494
Website
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Cell Mechanics, Electromechanical Transduction in Cochlear Outer Hair Cells and Soft Materials, Theoretical Modeling of Biological Systems, Biophysical Factors Mediating Gene Delivery, Aspirin-Like Molecules and Membrane Mechanics
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Richards-Kortum, Rebecca
|
Stanley C. Moore Professor Professor and Department Chair
Bioengineering
Rice University
|
Email
713-348-3823
Website
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Her research centers on new, non-invasive cancer detection technologies that use high-resolution, optical imaging; the use of fluorescent imaging agents for cancer detection; biophysical studies of the light-scattering properties of cells and tissues; and the use of fiber-optic sensors for in vivo detection of cancer
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Ridge, Kevin
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Associate Professor
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
|
Email
(713) 500-5908
Website
|
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Dynamic aspects of integral membrane protein structure, development and application of general approaches for the large-scale expression and purification of GPCR's
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Roberts, Norbert J.
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Professor of Microbiology and Immunology; Member, WHO Collaborating Center for Tropical Diseases
Department of Infectious Diseases
UT Medical Branch at Galveston
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Email
409-747-0236
Website
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Host defense mechanisms, antiviral immunity, influenza virus infections, influenza virus pathogenesis, respiratory syncytial virus (RSV) pathogenesis
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Rojo, Javier
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Professor
Statistics
Rice University
|
Email
713-348- 2797
Website
|
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Nonparametric Statistics, Survival Analysis and Reliability, Decision Theory, Partial Orders of Probability Distributions, Extreme Events
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Rosner, Gary
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Professor
Biostatistics & Applied Math
UT M. D. Anderson Cancer Center
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Email
713/563-4285
Website
|
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Bayesian methods; clinical trial design and analysis; longitudinal data models; population pharmacokinetics and pharmacodynamics; survival analysis
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Safe, Stephen
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Distinguished Professor; Director, Center for Environmental and Genetic Medicine
Veterinary Physiology and Pharmacology and Institute of Biosciences and Technology
TAMU
|
Email
979-845-5988
Website
|
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Toxicology and molecular biology of estrogenic and antiestrongenic compounds; molecular mechanisms of estrogen receptor and Ah receptor action and their crosstalk in breast cancer cells
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Saggau, Peter
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Professor
Division Of Neuroscience
Baylor College of Medicine
|
Email
713-798-5082
Website
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Modulation of synaptic transmission; The research interests in our lab are twofold: to understand the biophysics of central mammalian neurons that control both the communication between cells and their individual computational properties, and to develop advanced optical imaging tools for studying living brain tissue that help us to achieve this goal.
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San, Ka-Yiu
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E.D. Butcher Professor
Bioengineering
Rice University
|
Email
713-798-5361
Website
|
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Genomic and metabolic engineering; biochemical engineering; biotechnology. My research laboratory is mainly concerned with the development of new concepts and novel ways of altering metabolic routes in Escherichia coli using recombinant DNA technology to improve cellular activities and achieve more advanced production systems.
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Sastry, Jagannadha K.
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Professor
Immunology
UT M. D. Anderson Cancer Center
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Email
713-563-3304
Website
|
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HIV-AIDS; cervical cancer; vaccines; cellular immunology; synthetic peptides. Research in my laboratory focuses on understanding the molecular basis of immune disorders, and developing therapeutic and vaccine reagents. We are concentrating on two immune disorders: acquired immunodeficiency syndrome (AIDS) induced by human immunodeficiency virus (HIV), and cervical cancer associated with infection by human papillomavirus (HPV).
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Schein, Catherine
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Associate Professor
Biochemistry and Molecular Biology, Microbiology and Immunology
UT Medical Branch at Galveston
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Email
409-747-6843
Website
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Structure based design of antiviral and antibacterial drugs; Inhibiting protein aggregation in disease; Computer modeling of immune system complexes and allergy inducing proteins; Comparing the physicochemical properties of allergenic proteins and their epitopes; sequence analysis and databases of allergens (SDAP) and viral proteins (Flavitrack)
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Schmid, Michael
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Associate Professor
Biochemistry
Baylor College of Medicine
|
Email
713-798-5734
Website
|
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Image Processing and Electron Crystallography of Macromolecular Machines; Actin-based cytoskeletal structure
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Schonbrunn, Agnes
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Professor
Integrative Biology & Pharm
UT Health Science Center at Houston
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Email
(713) 500-7470
Website
|
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The mechanisms by which members of the seven-transmembrane domain (7TMD), G protein-coupled, receptor family respond to extracellular signals and the manner in which responsiveness is regulated.
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Schumacher, Maria A.
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Assistant Professor
Biochemistry & Molecular Biology
UT M. D. Anderson Cancer Center
|
Email
(713) 834-6392
Website
|
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Structural biology; crystallography; DNA partition/segregation; transcription regulation; nucleic acid-binding proteins
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Scott , David W
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Noah Harding Professor
Statistics
Rice University
|
Email
713-348-6037
Website
|
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Basic theoretical studies of multivariate probability density estimation, computationally intensive algorithms in statistical computing, and data exploration using advanced techniques in computer visualization
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Scuseria, Gustavo E
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Robert A. Welch Professor
Chemistry
Rice University
|
Email
713-348-4746
Website
|
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Theoretical chemistry, ab initio computational quantum chemistry, density functional theory, development of new methods for molecular electronic structure, and applications to nanostructures.
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Shamoo , Yousif
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Associate Professor
Biochemistry & Cell Biology
Rice University
|
Email
713-348-5493
Website
|
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sequence-specic RNA recognition, DNA replication and molecular evolution of microbial populations
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Shaulsky, Gadi
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Associate Professor
Mol. & Human Gen. Shaulsky
Baylor College of Medicine
|
Email
713-798-8082
Website
|
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Genetics and Functional Genomics of Dictyostelium Development
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Shaw , Chad A.
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Assistant Professor
Molecular and Human Genetics
Baylor College of Medicine
|
Email
713-798-8087
Website
|
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Galton-Watson processes, microarray normalization, and genome scale data mining.
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Siefert, Janet Louise
|
Faculty Fellow
Statistics
Rice University
|
Email
713-348-3891
Website
|
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Phylogeny reconstruction, prokaryotic biochemical systems and ecosystem evolution, origin of life, RNA's, and Astrobiology
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Silberg, Jonathan (Joff)
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Assistant Professor
Biochemistry & Cell Biology
Rice University
|
Email
713-348-3849
Website
|
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In our lab we are using a combination of biochemical, computational, and molecular biological methods to evolve folded and functional proteins with altered properties.
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Smith, Jack W.
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Dean & Professor
School of Health Information Sciences
UT Health Science Center at Houston
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Email
713-500-3925
Website
|
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Artificial intelligence, modeling problem-solving in healthcare, implementation of decision support and tutoring systems, modeling complex human problem-solving, application of cognitive science to understanding, human-computer interaction
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Sorensen , Danny C
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Noah Harding Professor; Department Chair
Comp & Applied Mathematics
Rice University
|
Email
713-348-5193
Website
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Numerical Linear Algebra, Numerical Analysis, Model Order Reduction, Control of Dynamical Systems, Numerical Optimization, Parallel Numerical Algorithms.
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Spanos , Pol D
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Lewis B. Ryon Professor
Mechanical Engr & Materials Sci
Rice University
|
Email
713-348-4909
Website
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Signal Processing, Response Determination, and Safety Assessment for Vibrations and Dynamics Problems in Aerospace, Biomedical, Marine, Petroleum, Structural, and Seismic Engineering
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Spudich, John
|
Professor/ R. Welch Dist Chr in Chemistry
Center for Membrane Biology, Dept of Biochemistry & Molecular Biology
UT Health Science Center at Houston
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Email
713-500-5473
Website
|
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Structure and function of photoactive membrane receptors and signal transduction triggered by light; rhodopsins and related heptahelical receptors.
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Stancel, George
|
Dr. John P. McGovern Professor and Dean
Graduate School of Biomedical Sciences
UT Health Science Center at Houston
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Email
713-500-9880
Website
|
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Regulation of cell proliferation by estrogens; growth factors and cellular oncogenes as mediators of hormonally induced growth; regulation of transcription by estrogens; regulation of angiogenesis by estrogens and antiestrogens; regulation of uterine function by steroid hormones and antihormones; regulation of breast and uterine cancer cell proliferation by estrogens; developmental effects of exposure to environmental estrogens and other endocrine disruptors
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Standifer, Kelly
|
Associate Professor
Pharmacology
University of Houston
|
Email
713-743-1771
Website
|
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ORL1 and m opioid receptor signaling; mechanisms of receptor cross-talk; opioid tolerance.
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Stivers, David
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Assistant Professor
Biostatistics
UT M. D. Anderson Cancer Center
|
Email
713-794-4161
Website
|
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Bioinformatics at the gene expression level to investigate the dynamic relationship between genes, Bioinformatics at the population level to investigate inheritance of genetic traits, Application of data mining techniques to problems in genetics, Mathematical genetics, Population structure and evolution, Forensic applications of genetics
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Strassmann , Joan E
|
Professor; Department Chair
Ecology & Evolutionary Biology
Rice University
|
Email
713-348-4922
Website
|
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Evolutionary biology, particularly social evolution and genetic conflicts of interest in social insects and social amoebae
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Subramanian , Devika
|
Professor
Computer Science
Rice University
|
Email
713-348-5661
Website
|
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Computational Biology, Conflict forecasting, Adaptive compilers, Machine learning, artificial intelligence, hybrid control, bioinformatics, cognitive science
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Takada, Shinako
|
Assistant Professor
Biochemistry & Molecular Biology
UT M. D. Anderson Cancer Center
|
Email
713-834-6275
Website
|
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Transcription, gene regulation, TATA-less promoters, hepatitis B virus
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Tao, Yizhi
|
Assistant Professor
Biochemistry &Cell Biology
Rice University
|
Email
713-348-4910
Website
|
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Regulation of virus genome replication; molecular mechanism of eukaryotic chromosome condensation. Influenza viruses cause highly contagious, acute respiratory illnesses which have inflicted humans since ancient times. Today influenza remains as a major concern of public health with frequent threat for widespread epidemics. Replication and expression of virus genome are crucial parts of the virus life cycle. Influenza virus RNA transcription is initiated using a capped RNA primer snatched from host mRNAs, whereas RNA replication does not require any primer and hence the replication products are not capped. Four viral proteins are needed for influenza virus RNA synthesis, including the three viral polymerase proteins PA, PB1 and PB2, and the viral nucleoprotein. Our laboratory uses the electron microscopy and three-dimensional reconstruction method to elucidate how influenza virus polymerase, the nucleoprotein, the viral RNA, and other essential components coordinate their functions to ensure both cap-dependent and cap-independent RNA synthesis. In particular, the structures of various polymerase-RNA complexes will be studied to characterize the transient molecular interactions. Detailed mechanistic studies of influenza virus polymerase will uncover fundamental rules underlying the unique gene expression and replication process shared by segmented, negative-strand and ambi-sense RNA viruses. New antiviral drugs can be designed against the polymerases of these viruses, targeting a few of their virus-specific activities.
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Tapia, Richard A
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University Professor; Maxfield-Oshman Chair in Engineering
Comp & Applied Mathematics
Rice University
|
Email
713-348-4049
Website
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Computational sciences; in particular, mathematical optimization theory and iterative methods for nonlinear problems.
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Thompson, Edward Bradley
|
Professor and Chair
Biochemistry & Molecular Biology
UT Medical Branch at Galveston
|
Email
409-772-3367
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This laboratory has a longstanding interest in the cellular and molecular actions of steroids, especially glucocorticoids and oxysterols.
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Travisano, Michael
|
Associate Professor
Biology & Biochemistry
University of Houston
|
Email
713-743-2627
Website
|
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the causes of biological diversity and complexity; Speciation in Saccharomyces,
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Tsai, Francis
|
Associate Professor
Biochemistry & Molecular Biology
Baylor College of Medicine
|
Email
713-798-8668
Website
|
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Structure and function of macromolecular complexes and supramolecular assemblies involved in protein folding, transcriptional regulation and cellular signaling.
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Vardi , Moshe Y
|
George Professor of Comp Eng
Computer Science
Rice University
|
Email
713-348-4834
Website
|
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Applications of logic to computer science, including database theory, finite-model theory, knowledge in multi-agent systems, computer-aided verification and reasoning, and teaching logic across the curriculum.
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Vekilov, Peter
|
Associate Professor
Chemical Engineering
University of Houston
|
Email
713-743-4315
Website
|
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Protein crystallization; physico-chemical aspects of sickle-cell anemia; kinetics and stability of crystal growth; Nucleation and phase transitions in protein solutions; Protein intermolecular interactions and phase diagrams; Crystallization of membrane proteins
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Wakil, Salih
|
Chairman Professor
Academic Department
Baylor College of Medicine
|
Email
713-798-4783
Website
|
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Structure, Function, and Regulation of the Multifunctional Enzymes, Acetyl-CoA Carboxylase and Fatty Acid Synthase
|
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Wang, Hongbin
|
Associate Professor
School of Health Information Sciences
UT Health Science Center at Houston
|
Email
713-500-3911
Website
|
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Spatial cognition; Medical decision making abductive/diagnostic reasoning; Human machine learning; Computational modeling; Human-computer interaction
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Warren , Joe D
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Professor
Computer Science
Rice University
|
Email
713-348-5728
Website
|
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algebraic geometry, computer-aided geometric design, mesh generation, symbolic computation, visualization, subdivision , wavelets
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Watowich, Stanley
|
Associate Professor
Biochemistry and Molecular Biology
UT Medical Branch at Galveston
|
Email
409-747-4749
Website
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Dr. Watowich has long-standing interest in virus structure, function, host-responses to infection, and antiviral drug development. The laboratory has solved the crystal structures of individual non-structural and structural proteins from alphaviruses, and carried out biochemical and biophysical studies of flavivirus and alphavirus proteins. Structures of intact RNA viruses and their assembly mechanisms are studied by electron cryomicroscopy, image reconstruction, and biophysical techniques. Structure-based computational drug discovery, in vitro inhibition assays, and cell- based replication assays are used to develop antiviral agents.
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Waxham, Neal
|
Professor
Neurobiology & Anatomy
UT Health Science Center at Houston
|
Email
713.500.5621
Website
|
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synaptic plasticity and transmission in the mammalian CNS
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Wendt, III, Richard
|
Professor
Imaging Physics
UT M. D. Anderson Cancer Center
|
Email
713-745-3250
Website
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Nuclear medicine, radionuclide imaging, telemedicine, radiation monitoring
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Wensel, Theodore G
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Professor
Biochemistry
Baylor College of Medicine
|
Email
713-798-6994
Website
|
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Structure and Dynamics of Signal Transducing Membranes
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Wheeler, David
|
Associate Professor, Director of Molecular Biology Computational Resource
Cell Biology
Baylor College of Medicine
|
Email
713-798-7206
Website
|
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Willson, Richard
|
Professor
Chemical and Biomolecular Engineering
University of Houston
|
Email
713-743-4308
Website
|
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Biomolecular recognition and its applications in separations and molecular diagnostics; the structural determinants of molecular recognition in complexes of proteins with recognition agents such as monoclonal antibodies and aptamers. Our primary techniques are expression, mutagenesis, fluorescence anisotropy (kinetics) and titration calorimetry.
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Wilson, John
|
Professor
Biochemistry
Baylor College of Medicine
|
Email
713-798-5760
Website
|
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Targeted Genome Modification; Basis for instability of trinucleotide repeats, oligonucleotide-based therapy for diseases of the eye
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Worley, Kim Carlyle
|
Associate Professor
Human Genome Sequencing Center
Baylor College of Medicine
|
Email
713-798-8292
|
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Human Genome Sequencing Center: annotating the sequences, pointing out where there are known genes, regulatory regions, repeat sequences and markers that can be used for navigating the genetic landscape.
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Zechiedrich, E. Lynn
|
AssociateProfessor
Molecular Virology & Microbiology
Baylor College of Medicine
|
Email
713-798-5126
Website
|
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DNA topoisomererases and antimicrobial resistance
|
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Zhang, Jiajie
|
Associate Dean for Research & Professor
School of Health Information Sciences
UT Health Science Center at Houston
|
Email
713-500-3922
Website
|
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Biomedical informatics, electronic health records, human-centered computing, cognitive science in medicine, information display and visualization, medical error, decision making
|
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Zhang, Shuxing
|
Assistant Professor
Experimental Therapeutics
UT M. D. Anderson Cancer Center
|
Email
713-745-2958
Website
|
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The fundamental foci of my research are to develop new computational methods and strategies that are urgently needed to efficiently deal with difficulties encountered in drug design and discovery, mainly in three areas: ligand-based drug design, structure-based drug design, and protein structure bioinformatics.
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Zhang, Wei
|
Associate Professor, Director of Cancer Genomics Core Laboratory
Pathology Research
UT M. D. Anderson Cancer Center
|
Email
713-745-1103
Website
|
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Cancer Genomics by gene and protein expression profiling.
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Zhang , Yin
|
Professor
Comp & Applied Mathematics
Rice University
|
Email
713-348-5744
Website
|
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Computational Mathematical Programming: Algorithm Development and Analysis; Interior point Algorithms for linear, semidefinite and nonlinear programming; Optimization Software Development; Optimization Problems in Computational Biology and Information Technology
|
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Zouridakis, George
|
Associate Professor, Director Biomedical Imaging Lab
Computer Sciences
University of Houston
|
Email
713-743-8656
Website
|
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Biomedical Imaging, Computational Biomedicine, Functional Brain Mapping, Biosignal Analysis and Modeling
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