BIOS 111 Fundamentals of Laboratory Work in the Biosciences (0-3-1)
Introduction to basic laboratory skills, including pipetting, solutions, dilutions, spectrophotometry, aseptic technique, record keeping, and similar basic laboratory activities. Work will consist of short investigative project. Recommendation: This course is recommended for students with very limited practical laboratory experience. Students wishing to take BIOS 211 will have to take this course or test out of it. See the course URL for instructions. Instructor permission required. Instructors: Beason Abmayr, Caprette
BIOS 113(F) Environmental Crisis Seminar: Water (1-0-1) Distribution course: Group III
Seminar topics may vary. Cross-list: Enst 113, Esci 113. Instructor:Dugan
BIOS 115 Freshman Seminar on Local Biology Research (1-0-1)
A 5-week seminar course to introduce freshmen prospective biologists to the excitement of research at Rice and the Medical Center and to provide context with which to think about facts presented in biosciences textbooks. Small groups will meet weekly with a graduate student or postdoctoral researcher to explore a published research article by a local lab, gaining background information about the subject and exposure to the research techniques. In the final session, the group will tour the lab that produced the featured article. Additional tours and activities TBA. All first-year students are eligible to enroll in BIOS 115 regardless of AP credit. This course meets in the second half of the semester. Instructors: Bartel, Phillips
BIOS 122(S) Fundamental Concepts in Biology (3-0-3) Restricted distribution course: Group III
Biological topics of current interest, covering advances in biotechnology, human health, agriculture, and the environment. Topics focus on the underlying biology, but may also include the social/political/economic impact. Each session is taught by an expert in that field with the assistance of a class coordinator. Instructor: Caprette
BIOS 201(F) Introductory Biology (3-0-3) Distribution course: Group III; Restricted distribution course: Group III
The first in an integrated sequence of four courses (Bios 201, 202, 301, 302). Chemistry and energetics, cell physiology, cell biology, Mendelian genetics, molecular genetics, developmental biology, and plant physiology. Instructor: Gustin
BIOS 202(S) Introductory Biology (3-0-3) Restricted distribution course: Group III
The second in an integrated sequence of four courses (Bios 201, 202, 301, 302). Molecular genetics, DNA technology, antibiotics and antivirals, animal behavior, evolution, ecology, diversity, and conservation biology. Prerequisite: Bios 201 or consent of instructor. Instructors: Siemann
BIOS 204(F) Environmental Sustainability: The Design & Practice of Community Agriculture (1-0-1)
The course introduces the fundamentals of community garden design and practice. Responsibilities will center on developing and improving the Rice Community Garden. The semester will begin with a short series of lectures by successful growers from the Houston community. A strong emphasis will be on learning and applying ecological principles to the practice of community agriculture. Class has required meetings outside of regular class time. Cross-list: Enst 204. Instructor: Rudgers
BIOS 211 Introduction to Experimental Biosciences (1-4-2)
Introduction to scientific method, principles of experimental design, selected research strategies, record keeping, and technical communication as related to biological science. Instructors: Eich, Caprette
BIOS 213 Introductory Lab Module in Ecology and Evolutionary Biology (1-4-1)
Experimental, laboratory and field studies of natural history, ecology, evolution, and animal behavior. Computer simulations of population genetics. Course will begin after mid-semester break in the Fall semester and after mid-term recess in the Spring semester. Instructor: TBA
BIOS 215 Bios Lab Teaching (hours variable)
Undergraduate teaching in a biosciences laboratory. Participate in weekly meetings and selected seminars; supervise up to 24 students in one or more laboratory sessions. Provide group and individual instruction to undergraduates during and outside of laboratory classes.
BIOS 301(F) Biochemistry (3-0-3)
The third in an integrated sequence of four courses (Bios 201, 202, 301, 302). Structure and function of proteins, enzymes, and nucleic acids; enzyme kinetics; glycolysis, aerobic metabolism, and energy coupling. Prerequisites: Chem 211, 212. Instructors: Olson, Shamoo
BIOS 302(S) Biochemistry (3-0-3, Group A) Distribution course: Group III
The final in an integrated sequence of four courses (Bios 201, 202, 301, 302). Introduction to metabolism, membranes, electron transport, oxidative phosphorylation, and regulation. Prerequisite: Bios 301 and Chem 211. Recommended prerequisite: Chem 212 Instructors: MacKenzie, Shamoo
BIOS 306 Independent Study for Ecology & Evolutionary Biology Undergraduates (hours variable)
Program of independent study for students with previous training in the biosciences. Includes a research paper. Students are expected to spend at least three hours per week in the laboratory for each semester hour of credit. If taken for two or more hours, counts as one required lab course but not as a Group A or Group B course. If receiving two or more credits, students will be required to participate in the university annual undergraduate symposium in the spring semesters. Biosciences Group B. Instructor permission required. Instructor: Strassmann
BIOS 307(S) Genetics: Science and Society (hours variable)
The course uses an interdisciplinary perspective. The course will cover biological basics of genes, DNA, and sequencing techniques; cultural and historical aspects to genetics, including essentialism and eugenics and policy issues. Also offered as Anth 314. Not open to Freshmen. Not offered in 2008.
BIOS 308 Advanced Modules in Plant Biochemistry (1-0-1)
Bio-organic lab module combining molecular biology to express plant terpene synthases in microbial systems with product structural analysis using GC-MS and NMR. Final lab reports will be in the format of a scientific publication. Instructor permission required. Prerequisites: CHEM 211 or BIOS 311. Cross-listed as CHEM 378. Instructor: McNeil
BIOS 309 Seminar in Research Methodology (2-0-2)
A course based on laboratory research done outside the university which will use seminars, discussion, and papers to develop communication skills in research. Permission of instructor to enroll. Not offered in 2008.
BIOS 310 Independent Study for Biochemistry & Cell Biology Undergraduates (1 to 4 hours credit each semester)
Independent research in Rice BCB faculty laboratories (section 1) or other Texas Medical Center laboratories (section 2). Students spend at least 3 hours per week in the laboratory for each semester hour of credit. If taken for 3 or more hours, counts as one required lab course but not as a Group A or Group B course. Requires a proposal abstract, weekly reports, and a research paper (fall semester) or a poster presentation (spring semester). Recommended: Instructor permission. Students are strongly advised to secure research advisors and register for the class well in advance of the start of classes. Instructor permission required. Instructors: Braam, Phillips
BIOS 311 Advanced Experimental Biosciences (2-4-2)
Advancement of biochemical laboratory methods, record keeping, technical communication skills, and research strategies. Students maintain a research quality laboratory notebook and submit a paper in the style of a journal article. Taught first half of each semester. If you find that you have a time conflict while registering for this course, please contact the instructor to inquire about Special Registration. BIOS 301 is required but it can be taken during the same semester as BIOS 311. Instructor: Beason Abmayr
BIOS 313(S) Experimental Synthetic Biology II (1-4-1)Introduction to the emerging field of synthetic biology. Focuses on molecular biological procedures commonly used to build and characterize synthetic genetic circuits. Students maintain a research quality laboratory notebook and submit a project proposal that promotes the development of novel biotechnology. Taught second half of spring semester. NOTICE: The course is closed to registration on Esther; to register, you must get the instructor’s signature on a Special Registration form available from the Office of the Registrar. Prerequisites: Bios 211 or permission of instructor. Instructor: Beason Abmayr
BIOS 316(F) Lab Module in Ecology (1-4-1)Field and lab experiments in ecology. Prerequisites: Bios 323 or 325 or permission of instructor. Instructor: Siemann
BIOS 317(S) Lab Module in Behavior (1-4-1)
Field experiments in behavior. Learn to formulate and test hypotheses on bird behavior using mockingbirds, grackles, and herons nesting on campus. Prerequisites: Bios 213 and 321 or permission of instructor. Instructor: Strassmann
BIOS 318(F) Lab Module in Microbiology (0-4-1)
Microbiological analysis of water, isolation, culture, observation, assay, and identification of bacteria, in the context of a simulated internship with a water/public health department. Starts the second half of the semester, self-scheduled after the first four formal meetings. Requires daily attention to cultures during the week. Limited enrollment. Prerequisite: Bios 211. Instructor: Caprette
BIOS 319(S) Tropical field biology
The course consists of 3-4 organizational meetings during the spring semester to assign readings and discuss field needs. Immediately following commencement, a 3.5 week field trip to Costa Rica will compromise the bulk of the course. Selection of students for the course is determined through an interview with the instructor. While a background in biology is desirable (minimally including the following courses: BIOS 201, 202, and 213), individuals lacking this background but having a special interest in the tropics are encouraged to enroll. Recommended prerequisite(s): BIOS 325, BIOS 336, BIOS 316, BIOS 317. Instructor permission required.
BIOS 320(S) Laboratory in Tissue Culture (3-0-3)
Introduction to tissue culture techniques, including cell passage, cell attachment and proliferation assays, and a transfection assay. Sections 1 and 2 are taught during the first half of the semester. Sections 3 and 4 are taught during the second half of the semester. Your registration for this course will not be accepted until you obtain Dr. Saterbak's signature on an Undergraduate Special Registration Request Form. Cross-list: Bioe 342. Instructor permission required. Instructor: Saterbak
BIOS 321(F) Animal Behavior (3-0-3, Group B) Distribution course: Group III
Evolutionary theory is used to evaluate behavioral adaptations of organisms to their environment. Prerequisites: Bios 201 and 202. Instructor: Strassmann
BIOS 323(S) Conservation Biology (3-0-3, Group B) Distribution course: Group III
The course is designed to give students a broad overview of conservation biology. Lectures and discussions will focus on conservation issues such as biodiversity, extinction, management, sustained yield, invasive species and preserve design. Prerequisites: Bios 201 and 202 or permission of instructor. Cross-listed as Enst 323. Instructor: Siemann
BIOS 325(F) Ecology (3-0-3, Group B) Distribution course: Group III
Study of population dynamics, species interactions, plant and animal community organization, and ecosystem function. Prerequisites: Bios 201 and 202. Instructor: Holland
BIOS 326(S) Insect Biology (3-0-3, Group B) Distribution course: Group III
This course addresses contemporary issues in ecology and evolution through the lens of insect diversity. Laboratory and field exercises provide hands-on experience with collection and curation of insect specimens. Readings span a broad literature (popular to technical). Writing and oral reports develop proficiency in scientific communication. 1 credit lab is required (BIOS 330). Group B. Instructor: Rudgers
BIOS 327(F) Biological Diversity Laboratory (1-0-1)
The course will examine (1) measures of biological diversity (taxic, molecular, and phylogenetic); (2) the ecological and evolutionary causes of biological diversity; (3) issues regarding the contribution of biological diversity to ecosystem function. A primary emphasis will be placed on experimental design and the measurement and estimation of biological diversity. Possible problems associated with the measurement and estimation of biological diversity will also be discussed. The course will take form of weekly preparatory meetings and culminate in a three-day exercise (taking place over fall break) at a field site in Texas where student will be responsible for designing and carrying out a study examining some aspect of biological diversity (taxic or functional group) with respect to such variables as habitat diversity, disturbance rate, or productivity. The course will emphasize oral presentations and written “publication” format papers. Prerequisites: Bios 201, 202 and 213. Instructor: TBA
BIOS 328(S) Evolution of Genes and Genomes (3-0-3, Group B) Distribution course: Group III
The course provides an overview of the evolution of genes and genomes. Using many examples, the course introduces databases and the Worldwide Web, and molecular and statistical methods used to study the evolution of genes and genomes. Broad-scale evolutionary patterns and medical applications based on genome analyses are presented. Prerequisites: Bios 201 and 202. Instructor: Kohn
BIOS 329(F) Animal biology and Physiology (3-0-3, Group B) Distribution course: Group III
The evolution and systematics of the animal kingdom with consideration of functional anatomy, comparative physiology, behavior, medical implications and resource management. Prerequisites: Bios 201 or 202 or permission of instructor. Instructor: Fisher
BIOS 330(S) Insect Biology Lab (1-0-1)
Required lab for Bios 326. Instructor: Rudgers
BIOS 331 Biology of Infectious Diseases (3-0-3)
This course gives a broad overview of the biology of infectious diseases using examples from humans, plants, and animals. Topics include diversity of diseases, mechanisms of disease transmission, epidemiology, population regulation, evolution of virulence, disease dynamics in natural communities and disease invasion and conservation biology. Prerequisites: Bios 201 and 202. Limited enrollment. Instructor: Rudolf
BIOS 332(S) Fundamentals of Systems Physiology (3-0-3, Group A)
This course will teach the fundamentals of physiology at the organism, tissue, and cellular levels. Emphasis will be on engineering aspects of physiology. This course includes several projects and written assignments. Prerequisites: Bios 201, Math 211. Cross-listed as Bioe 322. Instructors: Brown, Peek
BIOS 334(F) Evolution (3-0-3, Group B) Distribution course: Group III
Principles of biological evolution. Topics include natural selection, adaptation, molecular evolution, formation of new species, the fossil record, biogeography, and principles of classification. Prerequisites: Bios 202 or consent of instructor. Instructor: Queller
BIOS 336(S) Plant Diversity (3-0-3, Group B) Distribution course: Group III
The evolution and systematics of plants, with emphasis on flowering plants and biodiversity. Limited enrollment. Prerequisites: Bios 202. Instructor: Campbell
BIOS 337(S) Field Bird Biology Lab (1-0-1)
This course centers on a series of five field trips to diverse habitats for observing birds both immigrants and residents. Each will be preceded by a lecture and students will do two projects. Instructor permission required. Limited enrollment. Instructors: Lee, Queller, Strassmann
BIOS 338(F) Design and Analysis of Biological Experiments (3-0-3)
This course addresses methods to set up biological experiments that maximize the ability to draw meaningful conclusions. Designed (factorial, nested, split plot, repeated measures) and undesigned experiments (regression, correlation) will be considered, as well as analysis and interpretation of the data. Actual data sets from several areas of biology will be used for homework, demos, and projects. The student should have some previous exposure to statistics. Limited enrollment. Instructor: Jones
BIOS 339 Biometry (3-0-3)
This course provides advanced training in statistical analysis in ecology and evolutionary biology. Working with real data sets, we will explore diverse topics including breeding designs and quantitative genetics analysis, multiple regression, path analysis, structural equation modeling, bootstrapping and randomization tests, and nonmetric multidimensional scaling. Pre-requisites: Stat 280 OR Stat 305 OR Esci 451 OR Bios 338. Instructor: Rudgers
BIOS 340(F) Global Biogeochemical Cycles (3-0-3)
This course introduces students to the coupled nature of the biosphere, atmosphere and hydrosphere using as focal points elemental cycles such as those of carbon and nitrogen. Cross-list: Enst 340, Esci 340. Instructor: Masiello
BIOS 341(F) Cell Biology (3-0-3, Group A) Distribution course: Group III
Molecular mechanisms of the processes common to all cells, including exposition of structure, function, and biogenesis of all subcellular organelles. Emphasis will be on cytoplasmic events; molecular studies of transcription will be taught in Bios 344. Prerequisites: Bios 202. Instructor: McNew
BIOS 344(S) Molecular Biology and Genetics (3-0-3, Group A) Distribution course: Group III
Mendelian genetics, population genetics, mapping, gene expression and regulation, genetic engineering, DNA replication and recombination, human genetics, genetic disease and gene therapy. Recommended prerequisites: Bios 201, 202. Instructor: Stewart
BIOS 352(S) Physical Chemistry for the Biosciences (3-0-3, Group A) Distribution course: Group III
Study of selected aspects of physical chemistry as it relates to the biosciences. Includes thermodynamics, reaction rate theory, quantum mechanics, and atomic and molecular structure. Prerequisites: Chem 211 and 212, Phys 125 and 126, and Bios 301. Instructors: MacKenzie, Silberg
BIOS 361(S) Metabolic Engineering for Global Health Environments (3-0-3)
Importance of nutritional and pharmaceutical compounds, impact of cost of compounds on global health; Overview of biochemical pathways; Genetic engineering and molecular biology tools for ME; Nutritional molecules; Pharmaceuticals (antibiotics, tamiflu-against influenza virus; anti-parasite compounds against malaria and filaria diseases; anti-diarrhea treatments). Prerequisites: Bioe 260, Phys 126 and Math 102. Instructor: Bennett
BIOS 362(S Bioengineering for Global Health Environments (3-0-3)
Clinical trial design, regulation of medical technologies, medical technology assessment. Detailed case studies of vaccine development, diagnostic tests, cancer screening. Prerequisites: Bioe 260, Phys 126 and Math 102. Instructor: Richards-Kortum
BIOS 371 Seminar in contemporary biological and biomedical research
Close-up look at an area of contemporary biological and biomedical research in a small-group seminar setting. Each seminar will focus on a different area of research through reading and discussion of recent research articles in that focus area. The faculty discussion leader for each seminar will be drawn from Baylor College of Medicine, UT Health Science Center, MD Anderson Cancer Center, Rice or elsewhere in the Texas Medical Center. Pre-/co-requisite Bios 341 (Cell Biology) or Bios 301 (Biochemistry). Coordinator: Phillips
BIOS 372 Immunology (3-0-3, Group A)
Cellular and molecular basis of immune function in mammals. Prerequisites: Bios 201 and 202. Recommended prerequisites: 301 or 341. Instructor: Novotny
BIOS 385 Fundamentals of Cellular, Molecular, and Integrative Neuroscience (3-0-3, Group A)
Fundamental cellular, molecular and integrative mechanisms of neural function, including membrane and axon physiology, synaptic transmission and plasticity, sensory and motor systems, and development. Emphasis is on experimental evidence for current models. Open to juniors and seniors. Prerequisites: Bios 201, 202 and 301. Instructor: Caprette
BIOS 390 Transfer Credit in Biochemistry & Cell Biology (3-0-3, Group A)
For transfer of courses which have no current equivalent in the Rice curriculum, but which can be counted as Group A Biosciences courses in satisfying requirements for majors in Biosciences.
BIOS 391 Transfer Credit in Ecology & Evolutionary Biology (3-0-3, Group B)
For transfer of courses which have no current equivalent in the Rice curriculum, but which can be counted as Group B Biosciences courses in satisfying requirements for majors in Biosciences.
BIOS 393 Laboratory Transfer Credit in Biosciences (1-0-1)
For transfer of an advanced laboratory course in the biosciences that has no current equivalent in the Rice Biosciences curriculum. Any student may receive a maximum of 1 credit of BIOS 393.
BIOS 401(F), Bios 402(S) Undergraduate Honors Research (0-15-5 each semester, Group A)
Open only to undergraduate majors who meet specific requirements and with the permission of the research supervisor and chair. Registration for BIOS 401 implies a commitment to participate in research for at least 2 semesters. A substantial written report of the research work is required. A substantial written report of the research work is required. For those taking 401 and 402 in the same academic year, the student thesis report is due at the end of the second term, the spring Bios 402 term. Department permission required. Prerequisites: Bios 201, 202 and 301. Co-requisite: Bios 412. Instructor: Braam
BIOS 403(F), Bios 404(S) Undergraduate Honors Research in ecology and evolutionary biology (0-15-5 each semester, Group B)
Open only to undergraduate majors who meet specific requirements and with permission of the research supervisor and chair. Registration for Bios 403/404 implies a commitment to participate in research for at least 2 semesters. Department permission required. Instructors: Rudgers, Strassmann
BIOS 405(SU) Independent Research/Internship Program (0-15-5)
This independent research course offers multi-disciplinary training in the area of cellular engineering within the Departments of Bioengineering and Biochemistry & Cell Biology. Areas of research will include engineering of hard and soft tissue formation, cardiovascular tissue engineering, engineering cell surface interactions regulating movement and metabolic engineering. Students will conduct independent research under the supervision of a faculty mentor. Offered in summer.
BIOS 412(S) Undergraduate Research Seminar (1-0-1 each semester)
Discussion of current research in area under investigation. A substantial written report of the Bios 401/402 is required. Co-requisites: Bios 402. Instructors: Covington, Lwigale
BIOS 413 Experimental Molecular Biology (0-4-1)
Application of strategies in molecular biology to investigate gene expression and function in Arabidopsis. Emphasis on experimental design, data analysis, and data interpretation. Experience in preparation of a scientific poster. Taught second half of Spring semester. Instructor: Beason Abmayr, Eich
BIOS 415 Experimental Physiology (0-4-1)
Laboratory studies in membrane, nerve, and muscle physiology, with emphasis on experimental design, data analysis, and data interpretation. Starts the second half of the semester. Instructor: Caprette
BIOS 422(S) Endocrinology (3-0-3, Group A)
Study of the molecular and cellular mechanisms of hormone synthesis and of target cell responses. Study of the role of hormone action in mammalian physiological responses. Limited enrollment. Prerequisites: Bios 201, 202, 301 and 341. Instructor: Beckingham
BIOS 424(F) Microbiology and Biotechnology (3-0-3, Group A)Structure and function of microorganisms with emphasis on their environmental, industrial, and medical importance. Prerequisites: Bios 201, 202 and 301 or permission of instructor.
BIOS 425(F) Plant molecular Genetics and Development (3-0-3, Group A)
URL: http://www.owlnet.rice.edu/~bios425/
Novel aspects of plant biology and development with emphasis on molecular and genetic mechanisms. Plant responses to the environment and the use of bioengineering and other means to develop new plant products will also be covered. Prerequisites: Bios 201, 301, and 341 permission of instructor. Instructor: Bartel
BIOS 432(S) Advanced Evolutionary Biology (3-0-3, Group B)
Develop a critical understanding of evolutionary theory through lectures and discussion across a wide range of evolutionary topics. With the instructor’s help, students will use current papers to stimulate debate on the theories, philosophies and methods of the study of evolution. Prerequisites: Bios 201, 202 and either 321 or 334. Instructor: Strassmann
BIOS 433(S) Advanced Ecology (3-0-3, Group B)
Students will develop a critical understanding of the discipline of ecology through a combination of lectures and discussion that span a wide range of topics. With the instructor’s help, students will use current papers to stimulate debate on the theories, philosophies and methods of the study of populations, communities, and ecosystems. Prerequisites: Bios 201, 202 and 325 or permission of instructor. Instructor: Staff
BIOS 440(S) Enzyme Mechanics (3-0-3, Group A)
Enzymology is a biological extension of organic chemistry. This course will survey examples of enzyme-catalyzed reactions with emphasis on mechanisms. Enzymes that use catalytic cofactors (vitamins) will be covered, as will those that rely only on amino acid side chains. Also offered as Chem 440. Prerequisite: Chem 212. Instructor: Parry
BIOS 443/544 Advanced Concepts and Critical Analysis in Modern Developmental Biology (3-0-3, Group A)
An advanced undergraduate and graduate level course, dedicated to analysis and evaluation of scientific inquiry into animal development. Textbook-based lectures and discussions based on primary scientific literature are used to exemplify and evaluate concepts and methodology. Writing assignments, quizzes and a final exam will be used to evaluate performance. Instructor: Lane
BIOS 445(F) Advanced Molecular Biology and Genetics (3-0-3, Group A)
Molecular and genetic aspects of the regulation of gene expression as seen in simple prokaryotic systems and the model eukaryotic systems used for studies of development. Prerequisites: Bios 201, 202, 301, and 344. Instructors: Stern, Wagner
BIOS 464 Extracellular Matrix (3-0-3)
This course will address the biology, organization, mechanics, and turnover of extracellular matrix. There will be an emphasis on cells and cell-matrix interactions, matrix distributions in connective tissues and organs, techniques for measurement and modeling, changes with growth and aging, and tissue/matrix degradation including enzyme kinetics. Prerequisite: Cross-list: Bioe 464. Instructor: Grande-Allen
BIOS 481(F) Molecular Biophysics I (3-0-3, Group A)
Focus on principles of common biophysical methods used for study of conformations and dynamics of biological macromolecules and assemblies. Topics cover spectroscopic methods (absorption, fluorescence, circular dichroism, epr, NMR), transport processes, sedimentation, calorimetry, mass spectrometry, crystallography, cryo-electron microscopy, atomic force microscopy, ligand-protein interactions, protein folding, single molecule detection, computer simulations, functional genomics and laboratory evolution. Biological examples will be used to demonstrate merits and complementarity in each of the biophysical methods. Graduate/Undergraduate Equivalency: BIOS 551. Prerequisites: Bios 301 and 352 or permission of instructor. Instructor: Tao
BIOS 482(S) Molecular Biophysics II (3-0-3, Group A)
Advanced treatment of X-ray crystallography, NMR spectroscopy and electron microscopy. Emphasis on theory and application of these methods for the determination of the three-dimensional structure and dynamics of biological molecules and complexes. Recommended prerequisites: Bios 301 and 352. Limited enrollment. Instructors: Nikonowicz, Tao
BIOS 488(S) Advanced Cell Biology (3-0-3, Group A)
Review of literature on current biosciences research, with emphasis on human diseases, their treatment, and drug discovery. Instructor: Gomer
BIOS 525(F) Plant Molecular genetics and development (3-0-3)
Novel aspects of plant biology and development with emphasis on molecular and genetic mechanisms. Plant responses to the environment and the use of bioengineering and other means to develop new plant products will also be covered. Prerequisites: Bios 201, 301, and 341. Instructor: Bartel
BIOS 530(S) Laboratory Module in NMR Spectroscopy and Molecular Modeling (2-6-2)
The students will learn to set up, acquire, and process one-dimensional and basic two-dimensional NMR experiments. Spectral interpretation (resonance assignment and extraction of structural information) for nucleic acids and proteins using homonuclear and heteronuclear data will be performed. Enrollment limited to 12, with priority to graduate students. Prerequisites: Bios 352 or permission of instructor. Corequisite: and 481. Instructors: Moran, Nikonowicz
BIOS 532(F) Laboratory Module in Optical Spectroscopy and Kinetics (2-6-2)
Students learn the principles behind fluorescence, circular dichroism, analytical ultracentrifugation, spectroscopy and rapid kinetics by carrying out experiments with genetically engineered proteins and state-of-the-art equipment. Data will be interpreted and manipulated using curve-fitting and graphics software. Offered second half of the semester. Limited enrollment. Recommended Prerequisite(s): BIOS 352 or equivalent. Concurrent or previous enrollment in BIOS 481 or BIOS 551. Instructor: Nikonowicz
BIOS 533(F) Bioinformatics (3-0-3)
An introduction to the emerging field of bioinformatics. A series of lectures, combined with hands-on exercises. The topics to be discussed include sequence comparison, structure analysis, phylogenetics, database searching, microarrays and proteomics. Recommended prerequisite: Bios 301 or permission of instructor. Instructor: Cates
BIOS 535(S) Practical X-Ray Crystallography (3-0-3)
This is an introduction to macromolecular crystallography with emphasis on crystallization methods, data acquisition, processing, and molecular model-building. Approaches to solving structures will be discussed, as well as refinement of molecular models. Offered second half of the semester. Corequisites: Bios 482 or 552. Instructor: Tao
BIOS 541(F), Bios 542(S) Special Topics in Ecology & Evolutionary Biology (3-0-3)
Course may be repeated for credit. Instructor: Strassmann
BIOS 543(S) Secondary Metabolism (3-0-3, Group A)
A survey of the biosynthetic pathways leading to the major classes of natural products. Topics covered include the use of radioactive and stable isotopes, the synthesis of labeled organic compounds, mechanistic investigations of secondary metabolic enzymes, and the cloning and characterization of secondary metabolic genes. Also offered as Chem 543. Offered alternate years. Prerequisite: Chem 212. Instructor: Parry
BIOS 544(S) Advanced Concepts and Critical Analysis in Modern Developmental Biology (3-0-3, Group A)
An advanced undergraduate and graduate level course, dedicated to analysis and evaluation of scientific inquiry into animal development. Textbook-based lectures and discussions based on primary scientific literature are used to exemplify and evaluate concepts and methodology. Writing assignments, quizzes and a final exam will be used to evaluate performance. Graduate/Undergraduate Equivalency: BIOS 443. Prerequisites: Bios 201, 202, 301, 341 or permission of instructor. Instructor: Lane
BIOS 545(F) Advanced Molecular Biology and Genetics (3-0-3)
Molecular and genetic aspects of the regulation of gene expression as seen in simple prokaryotic systems and the model eukaryotic systems used for studies of development. Prerequisites: Bios 201, 202, 301, and 344. Instructors: Stern, Wagner
BIOS 551(F) Molecular Biophysics (3-0-3)
Focus on principles of common biophysical methods used for study of conformations and dynamics of biological macromolecules and assemblies. Topics cover spectroscopic methods (absorption, fluorescence, circular dichroism, epr, NMR), transport processes, sedimentation, calorimetry, mass spectrometry, crystallography, cryo-electron microscopy, atomic force microscopy, ligand-protein interactions, protein folding, single molecule detection, computer simulations, functional genomics and laboratory evolution. Biological examples will be used to demonstrate merits and complementarity in each of the biophysical methods. Graduate/Undergraduate Equivalency: BIOS 481. Corequisite: Math 142. Prerequisites: Bios 301 and 352 or permission of instructor. Instructor: Tao
Bios 552(S) Molecular Biophysics II (3-0-3)
Advanced treatment of X-ray crystallography, NMR spectroscopy, and electron microscopy. Emphasis on theory and application of these methods for the determination of the three-dimensional structure and dynamics of biological molecules and complexes. Recommended prerequisites: Bios 301 and 352. Limited enrollment. Instructors: Nikonowicz, Tao
Bios 561(F) Topics in Evolution (2-0-2)
Review and discussion of the literature on current research in evolution. Prerequisite: graduate status or permission of chair or instructor. Instructors: Kohn, Queller, Strassmann, Whitney
Bios 562(S) Topics in Behavioral Ecology (2-0-2)
Review and discussion of literature on current research in animal behavior and evolution. Prerequisite: graduate standing or permission of chair or instructor. Course may be repeated for credit. Instructors: Kohn, Queller, Strassmann
Bios 563(F) Topics in Ecology (2-0-2)
Review and discussion of the literature on current research in ecology. Instructors: Holland, Rudgers, Rudolf
Bios 568(S) Topics in Biological Diversity (2-0-2)
Review and discussion of literature on current research in biological diversity. Instructor permission required. Instructors: Holland, Rudgers, Rudolf
BIOS 569(F) Core Course in Ecology and Evolutionary Biology (3-0-3)
Survey of topics in ecology and evolution taught by all EEB faculty.
BIOS 575(F) Introduction to Research (1-0-1)
Introduction of first-year graduate students to the research programs and laboratories of individual faculty members. Instructors: Staff
BIOS 576(F)/577(S) Foundations of Biotechnology (1-0-1)
Graduate level introduction to a wide range of research methods in biosciences and bioengineering. Individual faculty members from the Biosciences will each present practices and techniques for their areas of expertise. A web-based methods database will be constructed, with student involvement, from the library of lectures. Also offered as Bioe 576/577. Instructor: West
BIOS 578 Biotechnology Practicum (1-0-1)
This course is part of the NIH Biotechnology Training Program and is limited to program participants. Students will receive exposure and training in cutting edge concepts and technologies. Cross-listed as Bioe 578. Instructors: Beason, Silberg, West
BIOS 581(F) Graduate Seminar in Biochemistry & cell biology (1-0-1 each semester)
A discussion of selected research topics. Required of all Biochemistry & Cell Biology graduate students. Instructors: Beckingham, Stewart
BIOS 582(S) Graduate Seminar in Biochemistry & cell biology (1-0-1 each semester)
See Bios 581. Instructors: Stewart, Zhong
BIOS 583(F) Molecular Interactions (1-0-1)
Review of literature on current biosciences research. Open only to BCB graduate students. Instructors: Silberg
BIOS 585(F), Bios 586(S) Graduate Seminar in Ecology & Evolutionary Biology (1-0-1)
Faculty and student presentations on current research. Required of all Ecology & Evolutionary Biology graduate students. Instructor: Kohn
BIOS 587(S) Graduate Seminary for 1st Year Students in Biochemistry & Cell Biology (3-0-3)
Preparation and presentation of research proposals. Open only to BCB graduate students. Instructors: Nikonowicz, Stern
BIOS 588(S) Advanced Cell Biology (3-0-3, Group A)
Review of literature on current biosciences research, with emphasis on human diseases, their treatment, and drug discovery. Instructor: Gomer
BIOS 589(F) Computational Molecular Biophysics
This is a course designed for students in computationally-oriented biomedical and bioengineering majors to introduce the principles and methods used for the simulations and modeling of macromolecules of biological interest. Protein conformation and dynamics are emphasized. Empirical energy function and molecular dynamics calculations, as well as other approaches, are described. Specific biological problems are discussed to illustrate the methodology. Also offered as Bioe 589. Instructor: Ma
BIOS 590 Special Topics in Biochemistry & Cell Biology (hours variable)
Development of specific topic areas at the graduate level. Instructor: Staff
BIOS 591 Graduate Teaching (1-0-1)
Supervised instruction in teaching Ecology & Evolutionary Biology. Instructor: Strassmann
BIOS 592 Seminar in Computational Biology (1-0-1)
Discussion of selected research topics in computational biology. Course may be repeated for credit. Cross-list: Keck 592. Instructor: Staff
BIOS 593 Special in Biochemistry & Cell Biology (1-0-1)
Discussion of selected research topics in current plant biology literature. Instructors: Bartel, Braam
BIOS 594(F) Responsible Conduct of Research (1-0-1)
This course will consider ethical issues involving human and animal subjects, record keeping, publications, potential conflict of interest, and behavior toward colleagues, research fellows, students, and employees. Graduate students only. Also offered as Bioe 594. Limited enrollment. Instructor: Gomer
BIOS 599 Graduate Teaching in Biochemistry & Cell Biology (1-0-1 each semester)
Supervised instruction in teaching biochemistry & cell biology. Limited enrollment. Instructor: Braam
Bios 611(F), Bios 612(S) Research Seminar (3-0-3 each semester)
Discussion of individual laboratory research or current topics in particular areas. Instructors: Staff
Bios 621(F), Bios 622(S) Thesis Seminar (1-0-1 each semester)
BIOS 643(F) Mechanical and Thermodynamic Properties of Biomembranes ( 3-0-3)
The mechanical properties of membranes influence several biological processes including endocytosis, fusion, signaling an cellular differentiation. this course will cover the theoretical foundations for membrane mechanics, examine experimental methods for measuring membrane material properties, including nanomechanical and optical techniques, and emphasize the importance of membrane mechanics in bioengineering applications. Cross-list: Phys 643.
Instructor permission required. Instructor: Raphael
BIOS 701 Graduate Lab Research I (1 to 4)
BIOS 702 Graduate Lab Research II (1 to 4)
Graduate research in Biochemistry & Cell Biology. Designed for short term laboratory projects for first year graduate students. Recommended prerequisite: Graduate standing in Biochemistry & Cell Biology. Instructors: Braam
BIOS 777 Visiting Research
Bios 800 Graduate Research (hours variable).
Bios 801 EEB Graduate Research (hours variable).
